Closing the access barrier for effective anti-malarials in the private sector in rural Uganda: consortium for ACT private sector subsidy (CAPSS) pilot study
Abstract Background Artemisinin-based combination therapy (ACT), the treatment of choice for uncomplicated falciparum malaria, is unaffordable and generally inaccessible in the private sector, the first port of call for most malaria treatment across rural Africa. Between August 2007 and May 2010, th...
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ftdoajarticles:oai:doaj.org/article:ccf735cd05ba4a768d77732d6f9dbc40 2023-05-15T15:19:03+02:00 Closing the access barrier for effective anti-malarials in the private sector in rural Uganda: consortium for ACT private sector subsidy (CAPSS) pilot study Talisuna Ambrose O Daumerie Penny Balyeku Andrew Egan Timothy Piot Bram Coghlan Renia Lugand Maud Bwire Godfrey Rwakimari John Ndyomugyenyi Richard Kato Fred Byangire Maria Kagwa Paul Sebisubi Fred Nahamya David Bonabana Angela Mpanga-Mukasa Susan Buyungo Peter Lukwago Julius Batte Allan Nakanwagi Grace Tibenderana James Nayer Kinny Reddy Kishore Dokwal Nilesh Rugumambaju Sylvester Kidde Saul Banerji Jaya Jagoe George 2012-10-01T00:00:00Z https://doi.org/10.1186/1475-2875-11-356 https://doaj.org/article/ccf735cd05ba4a768d77732d6f9dbc40 EN eng BMC http://www.malariajournal.com/content/11/1/356 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-11-356 1475-2875 https://doaj.org/article/ccf735cd05ba4a768d77732d6f9dbc40 Malaria Journal, Vol 11, Iss 1, p 356 (2012) Falciparum malaria Artemisinin-based combination therapy Subsidized medicines “ACT with a leaf” Private sector Affordable medicines facility- malaria Uganda Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2012 ftdoajarticles https://doi.org/10.1186/1475-2875-11-356 2022-12-31T07:15:26Z Abstract Background Artemisinin-based combination therapy (ACT), the treatment of choice for uncomplicated falciparum malaria, is unaffordable and generally inaccessible in the private sector, the first port of call for most malaria treatment across rural Africa. Between August 2007 and May 2010, the Uganda Ministry of Health and the Medicines for Malaria Venture conducted the Consortium for ACT Private Sector Subsidy (CAPSS) pilot study to test whether access to ACT in the private sector could be improved through the provision of a high level supply chain subsidy. Methods Four intervention districts were purposefully selected to receive branded subsidized medicines - “ACT with a leaf”, while the fifth district acted as the control. Baseline and evaluation outlet exit surveys and retail audits were conducted at licensed and unlicensed drug outlets in the intervention and control districts. A survey-adjusted, multivariate logistic regression model was used to analyse the intervention’s impact on: ACT uptake and price; purchase of ACT within 24 hours of symptom onset; ACT availability and displacement of sub-optimal anti-malarial. Results At baseline, ACT accounted for less than 1% of anti-malarials purchased from licensed drug shops for children less than five years old. However, at evaluation, “ACT with a leaf” accounted for 69% of anti-malarial purchased in the interventions districts. Purchase of ACT within 24 hours of symptom onset for children under five years rose from 0.8% at baseline to 26.2% (95% CI: 23.2-29.2%) at evaluation in the intervention districts. In the control district, it rose modestly from 1.8% to 5.6% (95% CI: 4.0-7.3%). The odds of purchasing ACT within 24 hours in the intervention districts compared to the control was 0.46 (95% CI: 0.08-2.68, p=0.4) at baseline and significant increased to 6.11 (95% CI: 4.32-8.62, p<0.0001) at evaluation. Children less than five years of age had “ACT with a leaf” purchased for them more often than those aged above five years. There was no evidence of ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 11 1 |
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English |
topic |
Falciparum malaria Artemisinin-based combination therapy Subsidized medicines “ACT with a leaf” Private sector Affordable medicines facility- malaria Uganda Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Falciparum malaria Artemisinin-based combination therapy Subsidized medicines “ACT with a leaf” Private sector Affordable medicines facility- malaria Uganda Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Talisuna Ambrose O Daumerie Penny Balyeku Andrew Egan Timothy Piot Bram Coghlan Renia Lugand Maud Bwire Godfrey Rwakimari John Ndyomugyenyi Richard Kato Fred Byangire Maria Kagwa Paul Sebisubi Fred Nahamya David Bonabana Angela Mpanga-Mukasa Susan Buyungo Peter Lukwago Julius Batte Allan Nakanwagi Grace Tibenderana James Nayer Kinny Reddy Kishore Dokwal Nilesh Rugumambaju Sylvester Kidde Saul Banerji Jaya Jagoe George Closing the access barrier for effective anti-malarials in the private sector in rural Uganda: consortium for ACT private sector subsidy (CAPSS) pilot study |
topic_facet |
Falciparum malaria Artemisinin-based combination therapy Subsidized medicines “ACT with a leaf” Private sector Affordable medicines facility- malaria Uganda Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background Artemisinin-based combination therapy (ACT), the treatment of choice for uncomplicated falciparum malaria, is unaffordable and generally inaccessible in the private sector, the first port of call for most malaria treatment across rural Africa. Between August 2007 and May 2010, the Uganda Ministry of Health and the Medicines for Malaria Venture conducted the Consortium for ACT Private Sector Subsidy (CAPSS) pilot study to test whether access to ACT in the private sector could be improved through the provision of a high level supply chain subsidy. Methods Four intervention districts were purposefully selected to receive branded subsidized medicines - “ACT with a leaf”, while the fifth district acted as the control. Baseline and evaluation outlet exit surveys and retail audits were conducted at licensed and unlicensed drug outlets in the intervention and control districts. A survey-adjusted, multivariate logistic regression model was used to analyse the intervention’s impact on: ACT uptake and price; purchase of ACT within 24 hours of symptom onset; ACT availability and displacement of sub-optimal anti-malarial. Results At baseline, ACT accounted for less than 1% of anti-malarials purchased from licensed drug shops for children less than five years old. However, at evaluation, “ACT with a leaf” accounted for 69% of anti-malarial purchased in the interventions districts. Purchase of ACT within 24 hours of symptom onset for children under five years rose from 0.8% at baseline to 26.2% (95% CI: 23.2-29.2%) at evaluation in the intervention districts. In the control district, it rose modestly from 1.8% to 5.6% (95% CI: 4.0-7.3%). The odds of purchasing ACT within 24 hours in the intervention districts compared to the control was 0.46 (95% CI: 0.08-2.68, p=0.4) at baseline and significant increased to 6.11 (95% CI: 4.32-8.62, p<0.0001) at evaluation. Children less than five years of age had “ACT with a leaf” purchased for them more often than those aged above five years. There was no evidence of ... |
format |
Article in Journal/Newspaper |
author |
Talisuna Ambrose O Daumerie Penny Balyeku Andrew Egan Timothy Piot Bram Coghlan Renia Lugand Maud Bwire Godfrey Rwakimari John Ndyomugyenyi Richard Kato Fred Byangire Maria Kagwa Paul Sebisubi Fred Nahamya David Bonabana Angela Mpanga-Mukasa Susan Buyungo Peter Lukwago Julius Batte Allan Nakanwagi Grace Tibenderana James Nayer Kinny Reddy Kishore Dokwal Nilesh Rugumambaju Sylvester Kidde Saul Banerji Jaya Jagoe George |
author_facet |
Talisuna Ambrose O Daumerie Penny Balyeku Andrew Egan Timothy Piot Bram Coghlan Renia Lugand Maud Bwire Godfrey Rwakimari John Ndyomugyenyi Richard Kato Fred Byangire Maria Kagwa Paul Sebisubi Fred Nahamya David Bonabana Angela Mpanga-Mukasa Susan Buyungo Peter Lukwago Julius Batte Allan Nakanwagi Grace Tibenderana James Nayer Kinny Reddy Kishore Dokwal Nilesh Rugumambaju Sylvester Kidde Saul Banerji Jaya Jagoe George |
author_sort |
Talisuna Ambrose O |
title |
Closing the access barrier for effective anti-malarials in the private sector in rural Uganda: consortium for ACT private sector subsidy (CAPSS) pilot study |
title_short |
Closing the access barrier for effective anti-malarials in the private sector in rural Uganda: consortium for ACT private sector subsidy (CAPSS) pilot study |
title_full |
Closing the access barrier for effective anti-malarials in the private sector in rural Uganda: consortium for ACT private sector subsidy (CAPSS) pilot study |
title_fullStr |
Closing the access barrier for effective anti-malarials in the private sector in rural Uganda: consortium for ACT private sector subsidy (CAPSS) pilot study |
title_full_unstemmed |
Closing the access barrier for effective anti-malarials in the private sector in rural Uganda: consortium for ACT private sector subsidy (CAPSS) pilot study |
title_sort |
closing the access barrier for effective anti-malarials in the private sector in rural uganda: consortium for act private sector subsidy (capss) pilot study |
publisher |
BMC |
publishDate |
2012 |
url |
https://doi.org/10.1186/1475-2875-11-356 https://doaj.org/article/ccf735cd05ba4a768d77732d6f9dbc40 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 11, Iss 1, p 356 (2012) |
op_relation |
http://www.malariajournal.com/content/11/1/356 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-11-356 1475-2875 https://doaj.org/article/ccf735cd05ba4a768d77732d6f9dbc40 |
op_doi |
https://doi.org/10.1186/1475-2875-11-356 |
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Malaria Journal |
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11 |
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1766349240887410688 |