Brucellosis Seropositivity in Animals and Humans in Ethiopia: A Meta-analysis.
BACKGROUND:The objectives of this study were to assess the heterogeneities of estimates and to estimate the seroprevalence of brucellosis in animals and humans in Ethiopia. METHODS/PRINCIPAL FINDINGS:Data from 70 studies covering 75879 animals and 2223 humans were extracted. Rose Bengal Plate Test (...
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ftdoajarticles:oai:doaj.org/article:cc62c6f4f2ef46da86cd5111e79db4cb 2023-05-15T15:09:35+02:00 Brucellosis Seropositivity in Animals and Humans in Ethiopia: A Meta-analysis. Getachew Tadesse 2016-10-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0005006 https://doaj.org/article/cc62c6f4f2ef46da86cd5111e79db4cb EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC5085315?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0005006 https://doaj.org/article/cc62c6f4f2ef46da86cd5111e79db4cb PLoS Neglected Tropical Diseases, Vol 10, Iss 10, p e0005006 (2016) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2016 ftdoajarticles https://doi.org/10.1371/journal.pntd.0005006 2022-12-31T11:40:43Z BACKGROUND:The objectives of this study were to assess the heterogeneities of estimates and to estimate the seroprevalence of brucellosis in animals and humans in Ethiopia. METHODS/PRINCIPAL FINDINGS:Data from 70 studies covering 75879 animals and 2223 humans were extracted. Rose Bengal Plate Test (RBPT) and Complement Fixation Test (CFT) in series were the most frequently used serological tests. A random effects model was used to calculate pooled prevalence estimates. The overall True Prevalence of brucellosis seropositivity in goats and sheep were estimated at 5.3% (95%CI = 3.5, 7.5) and 2.7% (95%CI = 1.8, 3.4), respectively, and 2.9% for each of camels and cattle. The prevalence was higher in post-pubertal than in pre-pubertal animals (OR = 3.1, 95% CI = 2.6, 3.7) and in the pastoral than in the mixed crop-livestock production system (OR = 2.8, 95%CI = 2.5, 3.2). The incidence rates of brucellosis in humans of pastoral and sedentary system origins were estimated at 160 and 28 per 100 000 person years, respectively. CONCLUSIONS:The seroprevalence of brucellosis is higher in goats than in other species. Its occurrence is evocative of its importance in the country in general and in the pastoral system in particular. Public awareness creation could reduce the transmission of Brucella spp. from animals to humans and the potential of livestock vaccination as a means of control of brucellosis needs to be assessed. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 10 10 e0005006 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Getachew Tadesse Brucellosis Seropositivity in Animals and Humans in Ethiopia: A Meta-analysis. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
BACKGROUND:The objectives of this study were to assess the heterogeneities of estimates and to estimate the seroprevalence of brucellosis in animals and humans in Ethiopia. METHODS/PRINCIPAL FINDINGS:Data from 70 studies covering 75879 animals and 2223 humans were extracted. Rose Bengal Plate Test (RBPT) and Complement Fixation Test (CFT) in series were the most frequently used serological tests. A random effects model was used to calculate pooled prevalence estimates. The overall True Prevalence of brucellosis seropositivity in goats and sheep were estimated at 5.3% (95%CI = 3.5, 7.5) and 2.7% (95%CI = 1.8, 3.4), respectively, and 2.9% for each of camels and cattle. The prevalence was higher in post-pubertal than in pre-pubertal animals (OR = 3.1, 95% CI = 2.6, 3.7) and in the pastoral than in the mixed crop-livestock production system (OR = 2.8, 95%CI = 2.5, 3.2). The incidence rates of brucellosis in humans of pastoral and sedentary system origins were estimated at 160 and 28 per 100 000 person years, respectively. CONCLUSIONS:The seroprevalence of brucellosis is higher in goats than in other species. Its occurrence is evocative of its importance in the country in general and in the pastoral system in particular. Public awareness creation could reduce the transmission of Brucella spp. from animals to humans and the potential of livestock vaccination as a means of control of brucellosis needs to be assessed. |
format |
Article in Journal/Newspaper |
author |
Getachew Tadesse |
author_facet |
Getachew Tadesse |
author_sort |
Getachew Tadesse |
title |
Brucellosis Seropositivity in Animals and Humans in Ethiopia: A Meta-analysis. |
title_short |
Brucellosis Seropositivity in Animals and Humans in Ethiopia: A Meta-analysis. |
title_full |
Brucellosis Seropositivity in Animals and Humans in Ethiopia: A Meta-analysis. |
title_fullStr |
Brucellosis Seropositivity in Animals and Humans in Ethiopia: A Meta-analysis. |
title_full_unstemmed |
Brucellosis Seropositivity in Animals and Humans in Ethiopia: A Meta-analysis. |
title_sort |
brucellosis seropositivity in animals and humans in ethiopia: a meta-analysis. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2016 |
url |
https://doi.org/10.1371/journal.pntd.0005006 https://doaj.org/article/cc62c6f4f2ef46da86cd5111e79db4cb |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 10, Iss 10, p e0005006 (2016) |
op_relation |
http://europepmc.org/articles/PMC5085315?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0005006 https://doaj.org/article/cc62c6f4f2ef46da86cd5111e79db4cb |
op_doi |
https://doi.org/10.1371/journal.pntd.0005006 |
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PLOS Neglected Tropical Diseases |
container_volume |
10 |
container_issue |
10 |
container_start_page |
e0005006 |
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1766340745069854720 |