Antiviral activity of animal venom peptides and related compounds
Abstract Viruses exhibit rapid mutational capacity to trick and infect host cells, sometimes assisted through virus-coded peptides that counteract host cellular immune defense. Although a large number of compounds have been identified as inhibiting various viral infections and disease progression, i...
Published in: | Journal of Venomous Animals and Toxins including Tropical Diseases |
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ftdoajarticles:oai:doaj.org/article:cc0e2620cee744ccab59f56087114c9e 2023-05-15T15:06:09+02:00 Antiviral activity of animal venom peptides and related compounds Élida Cleyse Gomes da Mata Caroline Barbosa Farias Mourão Marisa Rangel Elisabeth Ferroni Schwartz 2017-02-01T00:00:00Z https://doi.org/10.1186/s40409-016-0089-0 https://doaj.org/article/cc0e2620cee744ccab59f56087114c9e EN eng SciELO http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992017000100200&lng=en&tlng=en https://doaj.org/toc/1678-9199 1678-9199 doi:10.1186/s40409-016-0089-0 https://doaj.org/article/cc0e2620cee744ccab59f56087114c9e Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 23, Iss 0 (2017) Antiretroviral agents Antiviral agents HIV Scorpion venom Snake venom Amphibian venom Insect venom Marine animal peptides Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 article 2017 ftdoajarticles https://doi.org/10.1186/s40409-016-0089-0 2022-12-31T15:03:21Z Abstract Viruses exhibit rapid mutational capacity to trick and infect host cells, sometimes assisted through virus-coded peptides that counteract host cellular immune defense. Although a large number of compounds have been identified as inhibiting various viral infections and disease progression, it is urgent to achieve the discovery of more effective agents. Furthermore, proportionally to the great variety of diseases caused by viruses, very few viral vaccines are available, and not all are efficient. Thus, new antiviral substances obtained from natural products have been prospected, including those derived from venomous animals. Venoms are complex mixtures of hundreds of molecules, mostly peptides, that present a large array of biological activities and evolved to putatively target the biochemical machinery of different pathogens or host cellular structures. In addition, non-venomous compounds, such as some body fluids of invertebrate organisms, exhibit antiviral activity. This review provides a panorama of peptides described from animal venoms that present antiviral activity, thereby reinforcing them as important tools for the development of new therapeutic drugs. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Journal of Venomous Animals and Toxins including Tropical Diseases 23 1 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Antiretroviral agents Antiviral agents HIV Scorpion venom Snake venom Amphibian venom Insect venom Marine animal peptides Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 |
spellingShingle |
Antiretroviral agents Antiviral agents HIV Scorpion venom Snake venom Amphibian venom Insect venom Marine animal peptides Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 Élida Cleyse Gomes da Mata Caroline Barbosa Farias Mourão Marisa Rangel Elisabeth Ferroni Schwartz Antiviral activity of animal venom peptides and related compounds |
topic_facet |
Antiretroviral agents Antiviral agents HIV Scorpion venom Snake venom Amphibian venom Insect venom Marine animal peptides Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 |
description |
Abstract Viruses exhibit rapid mutational capacity to trick and infect host cells, sometimes assisted through virus-coded peptides that counteract host cellular immune defense. Although a large number of compounds have been identified as inhibiting various viral infections and disease progression, it is urgent to achieve the discovery of more effective agents. Furthermore, proportionally to the great variety of diseases caused by viruses, very few viral vaccines are available, and not all are efficient. Thus, new antiviral substances obtained from natural products have been prospected, including those derived from venomous animals. Venoms are complex mixtures of hundreds of molecules, mostly peptides, that present a large array of biological activities and evolved to putatively target the biochemical machinery of different pathogens or host cellular structures. In addition, non-venomous compounds, such as some body fluids of invertebrate organisms, exhibit antiviral activity. This review provides a panorama of peptides described from animal venoms that present antiviral activity, thereby reinforcing them as important tools for the development of new therapeutic drugs. |
format |
Article in Journal/Newspaper |
author |
Élida Cleyse Gomes da Mata Caroline Barbosa Farias Mourão Marisa Rangel Elisabeth Ferroni Schwartz |
author_facet |
Élida Cleyse Gomes da Mata Caroline Barbosa Farias Mourão Marisa Rangel Elisabeth Ferroni Schwartz |
author_sort |
Élida Cleyse Gomes da Mata |
title |
Antiviral activity of animal venom peptides and related compounds |
title_short |
Antiviral activity of animal venom peptides and related compounds |
title_full |
Antiviral activity of animal venom peptides and related compounds |
title_fullStr |
Antiviral activity of animal venom peptides and related compounds |
title_full_unstemmed |
Antiviral activity of animal venom peptides and related compounds |
title_sort |
antiviral activity of animal venom peptides and related compounds |
publisher |
SciELO |
publishDate |
2017 |
url |
https://doi.org/10.1186/s40409-016-0089-0 https://doaj.org/article/cc0e2620cee744ccab59f56087114c9e |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 23, Iss 0 (2017) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992017000100200&lng=en&tlng=en https://doaj.org/toc/1678-9199 1678-9199 doi:10.1186/s40409-016-0089-0 https://doaj.org/article/cc0e2620cee744ccab59f56087114c9e |
op_doi |
https://doi.org/10.1186/s40409-016-0089-0 |
container_title |
Journal of Venomous Animals and Toxins including Tropical Diseases |
container_volume |
23 |
container_issue |
1 |
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1766337801807200256 |