Dengue in Nicaragua, 1994: reintroduction of serotype 3 in the Americas
The principal aim of the report presented here is to describe the reappearance of dengue serotype 3 in the Americas, following a 17-year absence, through the recent experience of Nicaragua. In all, 356 serum samples obtained through Nicaragua's dengue monitoring system in October 1994 during an...
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Pan American Health Organization
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ftdoajarticles:oai:doaj.org/article:cad16459ec804e0c802e06f013f0b63b 2023-05-15T15:12:56+02:00 Dengue in Nicaragua, 1994: reintroduction of serotype 3 in the Americas María G. Guzmán Susana Vázquez Eric Martínez Mayling Álvarez Rosmary Rodríguez Gustavo Kourí José de los Reyes Francisco Acevedo 1997-03-01T00:00:00Z https://doi.org/10.1590/s1020-49891997000300005 https://doaj.org/article/cad16459ec804e0c802e06f013f0b63b EN ES PT eng spa por Pan American Health Organization http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49891997000300005&lng=en&tlng=en https://doaj.org/toc/1020-4989 1020-4989 doi:10.1590/s1020-49891997000300005 https://doaj.org/article/cad16459ec804e0c802e06f013f0b63b Revista Panamericana de Salud Pública, Vol 1, Iss 3, Pp 193-199 (1997) Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 1997 ftdoajarticles https://doi.org/10.1590/s1020-49891997000300005 2022-12-31T02:46:16Z The principal aim of the report presented here is to describe the reappearance of dengue serotype 3 in the Americas, following a 17-year absence, through the recent experience of Nicaragua. In all, 356 serum samples obtained through Nicaragua's dengue monitoring system in October 1994 during an epidemic were examined. Anti-dengue IgM antibodies were detected in 43% of these, with sera from 12 of the 18 areas covered by Nicaragua's local integrated health care systems yielding positive results. In addition, dengue virus was isolated from 5 of 24 sera obtained from patients with hemorrhagic symptoms, dengue 3 being isolated from 3 of these samples and dengue 1 from the other 2. A diagnosis of dengue with hemorrhagic manifestations or of hemorrhagic dengue was supported or confirmed by laboratory findings obtained from 26 of 39 patients hospitalized in León or Managua. The most frequent symptoms of 18 patients diagnosed as having dengue with hemorrhagic manifestations were fever, headache, vomiting, myalgia, arthralgia, and epistaxis. The remaining eight patients, diagnosed as having probable hemorrhagic dengue, exhibited fever, general malaise, hemorrhaging, thrombocytopenia, hemoconcentration, and hemagglutination-inhibition antibody titers ranging from 640 to 20 480. Overall, the reappearance of dengue serotype 3 in the Region was confirmed, together with its ability to produce cases of hemorrhagic dengue. At least in Nicaragua, it is apparent that the introduction of dengue serotype 3 has prompted an increase in the number of classical dengue and hemorrhagic dengue cases, a scenario that might constitute the grim prelude to future developments in the Americas if urgent attention is not given to controlling the disease's mosquito vector. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Grim ENVELOPE(-64.486,-64.486,-65.379,-65.379) Revista Panamericana de Salud Pública 1 3 193 199 |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
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English Spanish Portuguese |
topic |
Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 María G. Guzmán Susana Vázquez Eric Martínez Mayling Álvarez Rosmary Rodríguez Gustavo Kourí José de los Reyes Francisco Acevedo Dengue in Nicaragua, 1994: reintroduction of serotype 3 in the Americas |
topic_facet |
Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
The principal aim of the report presented here is to describe the reappearance of dengue serotype 3 in the Americas, following a 17-year absence, through the recent experience of Nicaragua. In all, 356 serum samples obtained through Nicaragua's dengue monitoring system in October 1994 during an epidemic were examined. Anti-dengue IgM antibodies were detected in 43% of these, with sera from 12 of the 18 areas covered by Nicaragua's local integrated health care systems yielding positive results. In addition, dengue virus was isolated from 5 of 24 sera obtained from patients with hemorrhagic symptoms, dengue 3 being isolated from 3 of these samples and dengue 1 from the other 2. A diagnosis of dengue with hemorrhagic manifestations or of hemorrhagic dengue was supported or confirmed by laboratory findings obtained from 26 of 39 patients hospitalized in León or Managua. The most frequent symptoms of 18 patients diagnosed as having dengue with hemorrhagic manifestations were fever, headache, vomiting, myalgia, arthralgia, and epistaxis. The remaining eight patients, diagnosed as having probable hemorrhagic dengue, exhibited fever, general malaise, hemorrhaging, thrombocytopenia, hemoconcentration, and hemagglutination-inhibition antibody titers ranging from 640 to 20 480. Overall, the reappearance of dengue serotype 3 in the Region was confirmed, together with its ability to produce cases of hemorrhagic dengue. At least in Nicaragua, it is apparent that the introduction of dengue serotype 3 has prompted an increase in the number of classical dengue and hemorrhagic dengue cases, a scenario that might constitute the grim prelude to future developments in the Americas if urgent attention is not given to controlling the disease's mosquito vector. |
format |
Article in Journal/Newspaper |
author |
María G. Guzmán Susana Vázquez Eric Martínez Mayling Álvarez Rosmary Rodríguez Gustavo Kourí José de los Reyes Francisco Acevedo |
author_facet |
María G. Guzmán Susana Vázquez Eric Martínez Mayling Álvarez Rosmary Rodríguez Gustavo Kourí José de los Reyes Francisco Acevedo |
author_sort |
María G. Guzmán |
title |
Dengue in Nicaragua, 1994: reintroduction of serotype 3 in the Americas |
title_short |
Dengue in Nicaragua, 1994: reintroduction of serotype 3 in the Americas |
title_full |
Dengue in Nicaragua, 1994: reintroduction of serotype 3 in the Americas |
title_fullStr |
Dengue in Nicaragua, 1994: reintroduction of serotype 3 in the Americas |
title_full_unstemmed |
Dengue in Nicaragua, 1994: reintroduction of serotype 3 in the Americas |
title_sort |
dengue in nicaragua, 1994: reintroduction of serotype 3 in the americas |
publisher |
Pan American Health Organization |
publishDate |
1997 |
url |
https://doi.org/10.1590/s1020-49891997000300005 https://doaj.org/article/cad16459ec804e0c802e06f013f0b63b |
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ENVELOPE(-64.486,-64.486,-65.379,-65.379) |
geographic |
Arctic Grim |
geographic_facet |
Arctic Grim |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista Panamericana de Salud Pública, Vol 1, Iss 3, Pp 193-199 (1997) |
op_relation |
http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49891997000300005&lng=en&tlng=en https://doaj.org/toc/1020-4989 1020-4989 doi:10.1590/s1020-49891997000300005 https://doaj.org/article/cad16459ec804e0c802e06f013f0b63b |
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https://doi.org/10.1590/s1020-49891997000300005 |
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Revista Panamericana de Salud Pública |
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193 |
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199 |
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