Genetic factors for short life span associated with evolution of the loss of flight ability
Abstract Acquisition or loss of flying ability is evolutionarily linked with maximum life span (MLS) in mammals and birds. Although ecological factors, such as extrinsic mortality, may lead to either shortened or extended life spans through natural selection, MLS is influenced by complex molecular a...
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ftdoajarticles:oai:doaj.org/article:ca86b7ad96d946218fbc8699036aed08 2023-05-15T16:06:00+02:00 Genetic factors for short life span associated with evolution of the loss of flight ability Atsushi Ikemoto Daiki X. Sato Takashi Makino Masakado Kawata 2020-06-01T00:00:00Z https://doi.org/10.1002/ece3.6342 https://doaj.org/article/ca86b7ad96d946218fbc8699036aed08 EN eng Wiley https://doi.org/10.1002/ece3.6342 https://doaj.org/toc/2045-7758 2045-7758 doi:10.1002/ece3.6342 https://doaj.org/article/ca86b7ad96d946218fbc8699036aed08 Ecology and Evolution, Vol 10, Iss 12, Pp 6020-6029 (2020) evolution of flying IGF2BP2 longevity maximum life span metabolism Ecology QH540-549.5 article 2020 ftdoajarticles https://doi.org/10.1002/ece3.6342 2022-12-31T06:07:57Z Abstract Acquisition or loss of flying ability is evolutionarily linked with maximum life span (MLS) in mammals and birds. Although ecological factors, such as extrinsic mortality, may lead to either shortened or extended life spans through natural selection, MLS is influenced by complex molecular and metabolic processes, and the genetic changes associated with flying ability that have led to either a longer or shorter MLS are unknown. Here, we examine the parallel evolution of flight in mammals and birds and investigate positively selected genes at branches where either the acquisition (in little brown bats and large flying foxes) or loss (in Adélie penguins, emperor penguins, common ostriches, emus, great spotted kiwis, little spotted kiwis, okarito brown kiwis, greater rheas, lesser rheas, and cassowaries) of flight abilities occurred. Although we found no shared genes under selection among all the branches of interest, 7 genes were found to be positively selected in 2 of the branches. Among the 7 genes, only IGF2BP2 is known to affect both life span and energy expenditure. The positively selected mutations detected in IGF2BP2 likely affected the functionality of the encoded protein. IGF2BP2, which has been reported to simultaneously prolong life span and increase energy expenditure, could be responsible for the evolution of shortened MLS associated with the loss of flying ability. Article in Journal/Newspaper Emperor penguins Directory of Open Access Journals: DOAJ Articles Ecology and Evolution 10 12 6020 6029 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
evolution of flying IGF2BP2 longevity maximum life span metabolism Ecology QH540-549.5 |
spellingShingle |
evolution of flying IGF2BP2 longevity maximum life span metabolism Ecology QH540-549.5 Atsushi Ikemoto Daiki X. Sato Takashi Makino Masakado Kawata Genetic factors for short life span associated with evolution of the loss of flight ability |
topic_facet |
evolution of flying IGF2BP2 longevity maximum life span metabolism Ecology QH540-549.5 |
description |
Abstract Acquisition or loss of flying ability is evolutionarily linked with maximum life span (MLS) in mammals and birds. Although ecological factors, such as extrinsic mortality, may lead to either shortened or extended life spans through natural selection, MLS is influenced by complex molecular and metabolic processes, and the genetic changes associated with flying ability that have led to either a longer or shorter MLS are unknown. Here, we examine the parallel evolution of flight in mammals and birds and investigate positively selected genes at branches where either the acquisition (in little brown bats and large flying foxes) or loss (in Adélie penguins, emperor penguins, common ostriches, emus, great spotted kiwis, little spotted kiwis, okarito brown kiwis, greater rheas, lesser rheas, and cassowaries) of flight abilities occurred. Although we found no shared genes under selection among all the branches of interest, 7 genes were found to be positively selected in 2 of the branches. Among the 7 genes, only IGF2BP2 is known to affect both life span and energy expenditure. The positively selected mutations detected in IGF2BP2 likely affected the functionality of the encoded protein. IGF2BP2, which has been reported to simultaneously prolong life span and increase energy expenditure, could be responsible for the evolution of shortened MLS associated with the loss of flying ability. |
format |
Article in Journal/Newspaper |
author |
Atsushi Ikemoto Daiki X. Sato Takashi Makino Masakado Kawata |
author_facet |
Atsushi Ikemoto Daiki X. Sato Takashi Makino Masakado Kawata |
author_sort |
Atsushi Ikemoto |
title |
Genetic factors for short life span associated with evolution of the loss of flight ability |
title_short |
Genetic factors for short life span associated with evolution of the loss of flight ability |
title_full |
Genetic factors for short life span associated with evolution of the loss of flight ability |
title_fullStr |
Genetic factors for short life span associated with evolution of the loss of flight ability |
title_full_unstemmed |
Genetic factors for short life span associated with evolution of the loss of flight ability |
title_sort |
genetic factors for short life span associated with evolution of the loss of flight ability |
publisher |
Wiley |
publishDate |
2020 |
url |
https://doi.org/10.1002/ece3.6342 https://doaj.org/article/ca86b7ad96d946218fbc8699036aed08 |
genre |
Emperor penguins |
genre_facet |
Emperor penguins |
op_source |
Ecology and Evolution, Vol 10, Iss 12, Pp 6020-6029 (2020) |
op_relation |
https://doi.org/10.1002/ece3.6342 https://doaj.org/toc/2045-7758 2045-7758 doi:10.1002/ece3.6342 https://doaj.org/article/ca86b7ad96d946218fbc8699036aed08 |
op_doi |
https://doi.org/10.1002/ece3.6342 |
container_title |
Ecology and Evolution |
container_volume |
10 |
container_issue |
12 |
container_start_page |
6020 |
op_container_end_page |
6029 |
_version_ |
1766401915111866368 |