Prevalence of Schistosoma mansoni infection in Ethiopia: a systematic review and meta-analysis
Abstract Background Schistosomiasis is a common helminthic infection in the tropics and subtropics, particularly in sub-Saharan African countries including Ethiopia. In these counties, Schistosoma mansoni infection is a significant public health problem due to the risk of reinfection and recurrent d...
Published in: | Tropical Diseases, Travel Medicine and Vaccines |
---|---|
Main Authors: | , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
BMC
2021
|
Subjects: | |
Online Access: | https://doi.org/10.1186/s40794-020-00127-x https://doaj.org/article/ca2ffdcad18b4a0584da6ff798fef347 |
id |
ftdoajarticles:oai:doaj.org/article:ca2ffdcad18b4a0584da6ff798fef347 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:ca2ffdcad18b4a0584da6ff798fef347 2023-05-15T15:13:28+02:00 Prevalence of Schistosoma mansoni infection in Ethiopia: a systematic review and meta-analysis Siraj Hussen Demissie Assegu Birkneh Tilahun Tadesse Techalew Shimelis 2021-02-01T00:00:00Z https://doi.org/10.1186/s40794-020-00127-x https://doaj.org/article/ca2ffdcad18b4a0584da6ff798fef347 EN eng BMC https://doi.org/10.1186/s40794-020-00127-x https://doaj.org/toc/2055-0936 doi:10.1186/s40794-020-00127-x 2055-0936 https://doaj.org/article/ca2ffdcad18b4a0584da6ff798fef347 Tropical Diseases, Travel Medicine and Vaccines, Vol 7, Iss 1, Pp 1-12 (2021) Meta-analysis S. mansoni Prevalence Ethiopia Arctic medicine. Tropical medicine RC955-962 article 2021 ftdoajarticles https://doi.org/10.1186/s40794-020-00127-x 2022-12-31T11:01:37Z Abstract Background Schistosomiasis is a common helminthic infection in the tropics and subtropics, particularly in sub-Saharan African countries including Ethiopia. In these counties, Schistosoma mansoni infection is a significant public health problem due to the risk of reinfection and recurrent disease despite implementing several rounds preventive chemotherapy. This systematic review and meta-analysis aimed at assessing the pooled prevalence of schistosomiasis in Ethiopia. Methods The PRISMA guidelines were followed to perform the systematic review and meta-analysis. Published studies from January 1999 to June 2020 were searched in Medline, PubMed, Google Scholar, EMBASE, HINARI, and Cochrane Library using key words including: “prevalence”, “incidence”, “schistosomiasis” “Bilharziasis”, “Bilharzia”, “S. mansoni “, “Ethiopia”. Heterogeneity of included studies was assessed using Cochran’s Q test and I 2 test statistics while publication bias was assessed using Egger’s test. Results Ninety-four studies were included in the systematic review and meta-analysis. The pooled prevalence of S. mansoni in Ethiopia was 18.0% (95%CI: 14.0–23.0). The southern region of Ethiopia had a higher S. mansoni prevalence of 25.9% (995% CI, 14.9–41.1) than the national prevalence. The burden of S. mansoni infection was also higher than the national average in rural areas and among men with pooled prevalence of 20.2% (95% CI, 13.2–28.5) and 28.5% (95%CI, 22.7,35.1), respectively. The trend analysis showed that the prevalence of S. mansoni infection in Ethiopia decreased over the past 15 years, potentially because of the repeated preventive chemotherapy. Conclusion The review unveiled a moderate prevalence of S. mansoni infection in Ethiopia. Targeted treatment of at-risk population groups ad high burden areas coupled with implementation of integrated vector control strategies are critical to address the burden of Schistosomiasis. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Prisma ENVELOPE(-58.767,-58.767,-69.200,-69.200) Tropical Diseases, Travel Medicine and Vaccines 7 1 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Meta-analysis S. mansoni Prevalence Ethiopia Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Meta-analysis S. mansoni Prevalence Ethiopia Arctic medicine. Tropical medicine RC955-962 Siraj Hussen Demissie Assegu Birkneh Tilahun Tadesse Techalew Shimelis Prevalence of Schistosoma mansoni infection in Ethiopia: a systematic review and meta-analysis |
topic_facet |
Meta-analysis S. mansoni Prevalence Ethiopia Arctic medicine. Tropical medicine RC955-962 |
description |
Abstract Background Schistosomiasis is a common helminthic infection in the tropics and subtropics, particularly in sub-Saharan African countries including Ethiopia. In these counties, Schistosoma mansoni infection is a significant public health problem due to the risk of reinfection and recurrent disease despite implementing several rounds preventive chemotherapy. This systematic review and meta-analysis aimed at assessing the pooled prevalence of schistosomiasis in Ethiopia. Methods The PRISMA guidelines were followed to perform the systematic review and meta-analysis. Published studies from January 1999 to June 2020 were searched in Medline, PubMed, Google Scholar, EMBASE, HINARI, and Cochrane Library using key words including: “prevalence”, “incidence”, “schistosomiasis” “Bilharziasis”, “Bilharzia”, “S. mansoni “, “Ethiopia”. Heterogeneity of included studies was assessed using Cochran’s Q test and I 2 test statistics while publication bias was assessed using Egger’s test. Results Ninety-four studies were included in the systematic review and meta-analysis. The pooled prevalence of S. mansoni in Ethiopia was 18.0% (95%CI: 14.0–23.0). The southern region of Ethiopia had a higher S. mansoni prevalence of 25.9% (995% CI, 14.9–41.1) than the national prevalence. The burden of S. mansoni infection was also higher than the national average in rural areas and among men with pooled prevalence of 20.2% (95% CI, 13.2–28.5) and 28.5% (95%CI, 22.7,35.1), respectively. The trend analysis showed that the prevalence of S. mansoni infection in Ethiopia decreased over the past 15 years, potentially because of the repeated preventive chemotherapy. Conclusion The review unveiled a moderate prevalence of S. mansoni infection in Ethiopia. Targeted treatment of at-risk population groups ad high burden areas coupled with implementation of integrated vector control strategies are critical to address the burden of Schistosomiasis. |
format |
Article in Journal/Newspaper |
author |
Siraj Hussen Demissie Assegu Birkneh Tilahun Tadesse Techalew Shimelis |
author_facet |
Siraj Hussen Demissie Assegu Birkneh Tilahun Tadesse Techalew Shimelis |
author_sort |
Siraj Hussen |
title |
Prevalence of Schistosoma mansoni infection in Ethiopia: a systematic review and meta-analysis |
title_short |
Prevalence of Schistosoma mansoni infection in Ethiopia: a systematic review and meta-analysis |
title_full |
Prevalence of Schistosoma mansoni infection in Ethiopia: a systematic review and meta-analysis |
title_fullStr |
Prevalence of Schistosoma mansoni infection in Ethiopia: a systematic review and meta-analysis |
title_full_unstemmed |
Prevalence of Schistosoma mansoni infection in Ethiopia: a systematic review and meta-analysis |
title_sort |
prevalence of schistosoma mansoni infection in ethiopia: a systematic review and meta-analysis |
publisher |
BMC |
publishDate |
2021 |
url |
https://doi.org/10.1186/s40794-020-00127-x https://doaj.org/article/ca2ffdcad18b4a0584da6ff798fef347 |
long_lat |
ENVELOPE(-58.767,-58.767,-69.200,-69.200) |
geographic |
Arctic Prisma |
geographic_facet |
Arctic Prisma |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Tropical Diseases, Travel Medicine and Vaccines, Vol 7, Iss 1, Pp 1-12 (2021) |
op_relation |
https://doi.org/10.1186/s40794-020-00127-x https://doaj.org/toc/2055-0936 doi:10.1186/s40794-020-00127-x 2055-0936 https://doaj.org/article/ca2ffdcad18b4a0584da6ff798fef347 |
op_doi |
https://doi.org/10.1186/s40794-020-00127-x |
container_title |
Tropical Diseases, Travel Medicine and Vaccines |
container_volume |
7 |
container_issue |
1 |
_version_ |
1766344015599370240 |