Therapeutic response and safety of different treatments for cutaneous leishmaniasis in patients: A retrospective cross-sectional study
Objective: To analyze the therapeutic response and safety of different treatments for cutaneous leishmaniasis, received by patients in the Program for the Study and Control of Tropical Diseases-PECET-Medellín-Colombia. Methods: This is a retrospective cross-sectional study of patients attended at PE...
Published in: | Asian Pacific Journal of Tropical Medicine |
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Wolters Kluwer Medknow Publications
2023
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Online Access: | https://doi.org/10.4103/1995-7645.380719 https://doaj.org/article/c9460a0e493b4e4caf950cc3766dba63 |
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ftdoajarticles:oai:doaj.org/article:c9460a0e493b4e4caf950cc3766dba63 2023-11-12T04:13:15+01:00 Therapeutic response and safety of different treatments for cutaneous leishmaniasis in patients: A retrospective cross-sectional study Nicolás Rozo Montoya Juliana Quintero Pulgarín Liliana López Carvajal 2023-01-01T00:00:00Z https://doi.org/10.4103/1995-7645.380719 https://doaj.org/article/c9460a0e493b4e4caf950cc3766dba63 EN eng Wolters Kluwer Medknow Publications http://www.apjtm.org/article.asp?issn=1995-7645;year=2023;volume=16;issue=7;spage=305;epage=312;aulast=Montoya https://doaj.org/toc/2352-4146 2352-4146 doi:10.4103/1995-7645.380719 https://doaj.org/article/c9460a0e493b4e4caf950cc3766dba63 Asian Pacific Journal of Tropical Medicine, Vol 16, Iss 7, Pp 305-312 (2023) cutaneous leishmaniasis systemic treatment local treatment combined treatment tropical neglected disease safety therapeutic response Arctic medicine. Tropical medicine RC955-962 article 2023 ftdoajarticles https://doi.org/10.4103/1995-7645.380719 2023-10-29T00:38:43Z Objective: To analyze the therapeutic response and safety of different treatments for cutaneous leishmaniasis, received by patients in the Program for the Study and Control of Tropical Diseases-PECET-Medellín-Colombia. Methods: This is a retrospective cross-sectional study of patients attended at PECET Research Center during 2016-2021. Relevant information regarding sociodemographic characteristics, history of leishmaniasis, characterization of current infection, treatment received, follow-up of therapeutic response and safety was collected from the medical records. Data were analyzed with Pearson's Chi - square association tests and Mann-Whitney U test using statistical software. Results: A total of 486 clinical records of patients were analyzed, and 356 received treatment. Eight different therapeutic alternatives (systemic, local and in combination) were analyzed. The therapeutic response of the different alternatives used (except thermotherapy) was higher than 50%. Most frequent adverse events were myalgias, arthralgias and headache, and vesicles for systemic and local treatment, respectively. Conclusions: Safety profile and performance of local therapeutic alternatives and combined schemes for the treatment of uncomplicated cutaneous leishmaniasis are an interesting option for the management of the disease. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Asian Pacific Journal of Tropical Medicine 16 7 305 312 |
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Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
cutaneous leishmaniasis systemic treatment local treatment combined treatment tropical neglected disease safety therapeutic response Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
cutaneous leishmaniasis systemic treatment local treatment combined treatment tropical neglected disease safety therapeutic response Arctic medicine. Tropical medicine RC955-962 Nicolás Rozo Montoya Juliana Quintero Pulgarín Liliana López Carvajal Therapeutic response and safety of different treatments for cutaneous leishmaniasis in patients: A retrospective cross-sectional study |
topic_facet |
cutaneous leishmaniasis systemic treatment local treatment combined treatment tropical neglected disease safety therapeutic response Arctic medicine. Tropical medicine RC955-962 |
description |
Objective: To analyze the therapeutic response and safety of different treatments for cutaneous leishmaniasis, received by patients in the Program for the Study and Control of Tropical Diseases-PECET-Medellín-Colombia. Methods: This is a retrospective cross-sectional study of patients attended at PECET Research Center during 2016-2021. Relevant information regarding sociodemographic characteristics, history of leishmaniasis, characterization of current infection, treatment received, follow-up of therapeutic response and safety was collected from the medical records. Data were analyzed with Pearson's Chi - square association tests and Mann-Whitney U test using statistical software. Results: A total of 486 clinical records of patients were analyzed, and 356 received treatment. Eight different therapeutic alternatives (systemic, local and in combination) were analyzed. The therapeutic response of the different alternatives used (except thermotherapy) was higher than 50%. Most frequent adverse events were myalgias, arthralgias and headache, and vesicles for systemic and local treatment, respectively. Conclusions: Safety profile and performance of local therapeutic alternatives and combined schemes for the treatment of uncomplicated cutaneous leishmaniasis are an interesting option for the management of the disease. |
format |
Article in Journal/Newspaper |
author |
Nicolás Rozo Montoya Juliana Quintero Pulgarín Liliana López Carvajal |
author_facet |
Nicolás Rozo Montoya Juliana Quintero Pulgarín Liliana López Carvajal |
author_sort |
Nicolás Rozo Montoya |
title |
Therapeutic response and safety of different treatments for cutaneous leishmaniasis in patients: A retrospective cross-sectional study |
title_short |
Therapeutic response and safety of different treatments for cutaneous leishmaniasis in patients: A retrospective cross-sectional study |
title_full |
Therapeutic response and safety of different treatments for cutaneous leishmaniasis in patients: A retrospective cross-sectional study |
title_fullStr |
Therapeutic response and safety of different treatments for cutaneous leishmaniasis in patients: A retrospective cross-sectional study |
title_full_unstemmed |
Therapeutic response and safety of different treatments for cutaneous leishmaniasis in patients: A retrospective cross-sectional study |
title_sort |
therapeutic response and safety of different treatments for cutaneous leishmaniasis in patients: a retrospective cross-sectional study |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2023 |
url |
https://doi.org/10.4103/1995-7645.380719 https://doaj.org/article/c9460a0e493b4e4caf950cc3766dba63 |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Medicine, Vol 16, Iss 7, Pp 305-312 (2023) |
op_relation |
http://www.apjtm.org/article.asp?issn=1995-7645;year=2023;volume=16;issue=7;spage=305;epage=312;aulast=Montoya https://doaj.org/toc/2352-4146 2352-4146 doi:10.4103/1995-7645.380719 https://doaj.org/article/c9460a0e493b4e4caf950cc3766dba63 |
op_doi |
https://doi.org/10.4103/1995-7645.380719 |
container_title |
Asian Pacific Journal of Tropical Medicine |
container_volume |
16 |
container_issue |
7 |
container_start_page |
305 |
op_container_end_page |
312 |
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1782331344567664640 |