Antioxidant antileishmanial cytotoxic and antimicrobial activities of a local plant Myrtus nivellei from Algeria Sahara
Objective: To study the phytochemical constituents and in vitro biological activities of hydromethanolic extract and fractions from Algerian Sahara Myrtus nivellei (M. nivellei) collected in Hoggar region and to identify the active fraction that can act as an alternative of commonly used antibiotics...
Published in: | Asian Pacific Journal of Tropical Biomedicine |
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Wolters Kluwer Medknow Publications
2017
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ftdoajarticles:oai:doaj.org/article:c8e41d3cc86741148895c4b5e7c78645 2023-05-15T15:08:26+02:00 Antioxidant antileishmanial cytotoxic and antimicrobial activities of a local plant Myrtus nivellei from Algeria Sahara Farah Ramdane Rym Essid Nadia Fares Dahmane El Ouassis Sana Aziz Mahfoud Hadj Mahammed Mohamed Didi Ould Hadj Ferid Limam 2017-08-01T00:00:00Z https://doi.org/10.1016/j.apjtb.2017.07.011 https://doaj.org/article/c8e41d3cc86741148895c4b5e7c78645 EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S2221169117307748 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2017.07.011 https://doaj.org/article/c8e41d3cc86741148895c4b5e7c78645 Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 8, Pp 702-707 (2017) Phenolic compounds Flavonoids Antioxidant activity Antimicrobial activity Antileishmanial activity Myrtus nivellei Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2017 ftdoajarticles https://doi.org/10.1016/j.apjtb.2017.07.011 2022-12-30T23:38:47Z Objective: To study the phytochemical constituents and in vitro biological activities of hydromethanolic extract and fractions from Algerian Sahara Myrtus nivellei (M. nivellei) collected in Hoggar region and to identify the active fraction that can act as an alternative of commonly used antibiotics and as antileishmanial or antioxidant agents. Methods: Phytochemical screening of M. nivellei aerial parts was realised according to the literature. Extract was firstly prepared by using aqueous methanol then fractionated with ethyl acetate and butanol solvents. Total phenolics, tannis and flavonoids, of the hydromethanolic extract and their fractions were determined by Folin–Ciocalteu method as gallic acid equivalents and by aluminium chloride as rutin equivalent respectively. Extract and fractions were tested for their antimicrobial and antiparasital activities against standard bacteria using agar diffusion method and two kinds of leishmania visceral and cutaneous. The antioxidant activities were realized using phosphomolybdenum, FRAP and DPPH tests. Results: Preliminary phytochemical screening exhibited the presence of flavonoids, tannins, saponins, and alkaloids. The experimental results showed that plant extract and fractions were high in phenolic compounds and exhibited an important role as antioxidant, antimicrobial and had a moderate antileishmanial activity. Conclusions: These observations lead us toward more studies in this field, so that we can get more benefits from our local Algerian medicinal plants. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Biomedicine 7 8 702 707 |
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Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Phenolic compounds Flavonoids Antioxidant activity Antimicrobial activity Antileishmanial activity Myrtus nivellei Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
spellingShingle |
Phenolic compounds Flavonoids Antioxidant activity Antimicrobial activity Antileishmanial activity Myrtus nivellei Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Farah Ramdane Rym Essid Nadia Fares Dahmane El Ouassis Sana Aziz Mahfoud Hadj Mahammed Mohamed Didi Ould Hadj Ferid Limam Antioxidant antileishmanial cytotoxic and antimicrobial activities of a local plant Myrtus nivellei from Algeria Sahara |
topic_facet |
Phenolic compounds Flavonoids Antioxidant activity Antimicrobial activity Antileishmanial activity Myrtus nivellei Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Objective: To study the phytochemical constituents and in vitro biological activities of hydromethanolic extract and fractions from Algerian Sahara Myrtus nivellei (M. nivellei) collected in Hoggar region and to identify the active fraction that can act as an alternative of commonly used antibiotics and as antileishmanial or antioxidant agents. Methods: Phytochemical screening of M. nivellei aerial parts was realised according to the literature. Extract was firstly prepared by using aqueous methanol then fractionated with ethyl acetate and butanol solvents. Total phenolics, tannis and flavonoids, of the hydromethanolic extract and their fractions were determined by Folin–Ciocalteu method as gallic acid equivalents and by aluminium chloride as rutin equivalent respectively. Extract and fractions were tested for their antimicrobial and antiparasital activities against standard bacteria using agar diffusion method and two kinds of leishmania visceral and cutaneous. The antioxidant activities were realized using phosphomolybdenum, FRAP and DPPH tests. Results: Preliminary phytochemical screening exhibited the presence of flavonoids, tannins, saponins, and alkaloids. The experimental results showed that plant extract and fractions were high in phenolic compounds and exhibited an important role as antioxidant, antimicrobial and had a moderate antileishmanial activity. Conclusions: These observations lead us toward more studies in this field, so that we can get more benefits from our local Algerian medicinal plants. |
format |
Article in Journal/Newspaper |
author |
Farah Ramdane Rym Essid Nadia Fares Dahmane El Ouassis Sana Aziz Mahfoud Hadj Mahammed Mohamed Didi Ould Hadj Ferid Limam |
author_facet |
Farah Ramdane Rym Essid Nadia Fares Dahmane El Ouassis Sana Aziz Mahfoud Hadj Mahammed Mohamed Didi Ould Hadj Ferid Limam |
author_sort |
Farah Ramdane |
title |
Antioxidant antileishmanial cytotoxic and antimicrobial activities of a local plant Myrtus nivellei from Algeria Sahara |
title_short |
Antioxidant antileishmanial cytotoxic and antimicrobial activities of a local plant Myrtus nivellei from Algeria Sahara |
title_full |
Antioxidant antileishmanial cytotoxic and antimicrobial activities of a local plant Myrtus nivellei from Algeria Sahara |
title_fullStr |
Antioxidant antileishmanial cytotoxic and antimicrobial activities of a local plant Myrtus nivellei from Algeria Sahara |
title_full_unstemmed |
Antioxidant antileishmanial cytotoxic and antimicrobial activities of a local plant Myrtus nivellei from Algeria Sahara |
title_sort |
antioxidant antileishmanial cytotoxic and antimicrobial activities of a local plant myrtus nivellei from algeria sahara |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2017 |
url |
https://doi.org/10.1016/j.apjtb.2017.07.011 https://doaj.org/article/c8e41d3cc86741148895c4b5e7c78645 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 8, Pp 702-707 (2017) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2221169117307748 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2017.07.011 https://doaj.org/article/c8e41d3cc86741148895c4b5e7c78645 |
op_doi |
https://doi.org/10.1016/j.apjtb.2017.07.011 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
7 |
container_issue |
8 |
container_start_page |
702 |
op_container_end_page |
707 |
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1766339797970845696 |