Visceral leishmaniasis in Ethiopia: an evolving disease.
Visceral leishmaniasis (also known as kala-azar) is classified as one of the most neglected tropical diseases. It is becoming a growing health problem in Ethiopia, with endemic areas that are continually spreading. The annual burden of visceral leishmaniasis (VL) in Ethiopia is estimated to be betwe...
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ftdoajarticles:oai:doaj.org/article:c83945aaacee408cbcf4fb6ea99ef023 2023-05-15T15:08:09+02:00 Visceral leishmaniasis in Ethiopia: an evolving disease. Samson Leta Thi Ha Thanh Dao Frehiwot Mesele Gezahegn Alemayehu 2014-09-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0003131 https://doaj.org/article/c83945aaacee408cbcf4fb6ea99ef023 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC4154678?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0003131 https://doaj.org/article/c83945aaacee408cbcf4fb6ea99ef023 PLoS Neglected Tropical Diseases, Vol 8, Iss 9, p e3131 (2014) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2014 ftdoajarticles https://doi.org/10.1371/journal.pntd.0003131 2022-12-31T14:27:51Z Visceral leishmaniasis (also known as kala-azar) is classified as one of the most neglected tropical diseases. It is becoming a growing health problem in Ethiopia, with endemic areas that are continually spreading. The annual burden of visceral leishmaniasis (VL) in Ethiopia is estimated to be between 4,500 and 5,000 cases, and the population at risk is more than 3.2 million. There has been a change in the epidemiology of VL in Ethiopia. Over the last decades, almost all cases and outbreaks of VL were reported from arid and semi-arid parts of the country; however, recent reports indicated the introduction of this disease into the highlands. Migration of labourers to and from endemic areas, climatic and environmental changes, and impaired immunity due to HIV/AIDS and malnutrition resulted in the change of VL epidemiology. HIV spurs the spread of VL by increasing the risk of progression from asymptomatic infection towards full VL. Conversely, VL accelerates the onset of AIDS. In Ethiopia, VL epidemiology remains complex because of the diversity of risk factors involved, and its control is becoming an increasing challenge. This paper reviews the changes in epidemiology of VL in Ethiopia and discusses some of the possible explanations for these changes. The prospects for novel approaches to VL control are discussed, as are the current and future challenges facing Ethiopia's public health development program. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Azar ENVELOPE(-63.733,-63.733,-64.983,-64.983) PLoS Neglected Tropical Diseases 8 9 e3131 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Samson Leta Thi Ha Thanh Dao Frehiwot Mesele Gezahegn Alemayehu Visceral leishmaniasis in Ethiopia: an evolving disease. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Visceral leishmaniasis (also known as kala-azar) is classified as one of the most neglected tropical diseases. It is becoming a growing health problem in Ethiopia, with endemic areas that are continually spreading. The annual burden of visceral leishmaniasis (VL) in Ethiopia is estimated to be between 4,500 and 5,000 cases, and the population at risk is more than 3.2 million. There has been a change in the epidemiology of VL in Ethiopia. Over the last decades, almost all cases and outbreaks of VL were reported from arid and semi-arid parts of the country; however, recent reports indicated the introduction of this disease into the highlands. Migration of labourers to and from endemic areas, climatic and environmental changes, and impaired immunity due to HIV/AIDS and malnutrition resulted in the change of VL epidemiology. HIV spurs the spread of VL by increasing the risk of progression from asymptomatic infection towards full VL. Conversely, VL accelerates the onset of AIDS. In Ethiopia, VL epidemiology remains complex because of the diversity of risk factors involved, and its control is becoming an increasing challenge. This paper reviews the changes in epidemiology of VL in Ethiopia and discusses some of the possible explanations for these changes. The prospects for novel approaches to VL control are discussed, as are the current and future challenges facing Ethiopia's public health development program. |
format |
Article in Journal/Newspaper |
author |
Samson Leta Thi Ha Thanh Dao Frehiwot Mesele Gezahegn Alemayehu |
author_facet |
Samson Leta Thi Ha Thanh Dao Frehiwot Mesele Gezahegn Alemayehu |
author_sort |
Samson Leta |
title |
Visceral leishmaniasis in Ethiopia: an evolving disease. |
title_short |
Visceral leishmaniasis in Ethiopia: an evolving disease. |
title_full |
Visceral leishmaniasis in Ethiopia: an evolving disease. |
title_fullStr |
Visceral leishmaniasis in Ethiopia: an evolving disease. |
title_full_unstemmed |
Visceral leishmaniasis in Ethiopia: an evolving disease. |
title_sort |
visceral leishmaniasis in ethiopia: an evolving disease. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2014 |
url |
https://doi.org/10.1371/journal.pntd.0003131 https://doaj.org/article/c83945aaacee408cbcf4fb6ea99ef023 |
long_lat |
ENVELOPE(-63.733,-63.733,-64.983,-64.983) |
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Arctic Azar |
geographic_facet |
Arctic Azar |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 8, Iss 9, p e3131 (2014) |
op_relation |
http://europepmc.org/articles/PMC4154678?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0003131 https://doaj.org/article/c83945aaacee408cbcf4fb6ea99ef023 |
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https://doi.org/10.1371/journal.pntd.0003131 |
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PLoS Neglected Tropical Diseases |
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9 |
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