Enhanced omega‐3 index after long‐ versus short‐chain omega‐3 fatty acid supplementation in dogs
Abstract Background The Omega‐3 Index is a test that measures the amount of the long‐chain omega‐3 polyunsaturated fatty acids (n‐3 PUFAs), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in red blood cell membranes, which is expressed as a percentage of all fatty acids. However, alpha‐li...
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ftdoajarticles:oai:doaj.org/article:c831ec5cfc354585b5f0ef4d62525f82 2023-05-15T13:51:44+02:00 Enhanced omega‐3 index after long‐ versus short‐chain omega‐3 fatty acid supplementation in dogs Tonje E. Dominguez Kiranpreet Kaur Lena Burri 2021-03-01T00:00:00Z https://doi.org/10.1002/vms3.369 https://doaj.org/article/c831ec5cfc354585b5f0ef4d62525f82 EN eng Wiley https://doi.org/10.1002/vms3.369 https://doaj.org/toc/2053-1095 2053-1095 doi:10.1002/vms3.369 https://doaj.org/article/c831ec5cfc354585b5f0ef4d62525f82 Veterinary Medicine and Science, Vol 7, Iss 2, Pp 370-377 (2021) Alpha‐linolenic acid astaxanthin krill oil flaxseed oil Omega‐3 Index omega‐3 long‐chain polyunsaturated fatty acids Veterinary medicine SF600-1100 article 2021 ftdoajarticles https://doi.org/10.1002/vms3.369 2022-12-31T07:59:32Z Abstract Background The Omega‐3 Index is a test that measures the amount of the long‐chain omega‐3 polyunsaturated fatty acids (n‐3 PUFAs), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in red blood cell membranes, which is expressed as a percentage of all fatty acids. However, alpha‐linolenic acid (ALA) from flaxseed oil, which is a short‐chain n‐3 PUFA, is often promoted in pet feed as a n‐3 source, implicitly assuming it is an effective precursor of EPA and DHA. Objective This study was aimed to compare the effect of supplementation with a plant‐based short‐chain n‐3 PUFA source (flaxseed oil, FSO) with a marine long‐chain n‐3 PUFA source (astaxanthin krill oil, AKO) to increase the Omega‐3 Index in dogs. Methods Ten adult Alaskan Huskies of both genders were supplemented daily with 1,155 mg of EPA/DHA from AKO, whereas another 10 dogs received 1,068 mg ALA from flaxseed oil for 6 weeks. Fatty acid and Omega‐3 Index measurements of the two groups were taken after 0, 3 and 6 weeks for comparison. Results The EPA and DHA concentrations increased significantly only in the dogs fed with AKO resulting in a significant increase in mean Omega‐3 Index, from 1.68% at baseline to 2.7% after 6 weeks of supplementation (p < .0001). On the contrary, both EPA and DHA concentrations decreased significantly in the dogs fed with FSO, which led to a significant decrease in mean Omega‐3 Index from 1.6% at baseline to 0.96% at study end (p < .0001). Conclusions The results showed that supplementation of AKO from Antarctic krill led to a significant increase in the Omega‐3 Index in comparison to FSO in dogs. This suggests that preformed marine EPA and DHA sources are needed in dog feeds, as the dietary requirements proposed by feed industry organizations are not met with conversion from short‐chain n‐3 fatty acids. Article in Journal/Newspaper Antarc* Antarctic Antarctic Krill Huskies Directory of Open Access Journals: DOAJ Articles Antarctic Veterinary Medicine and Science 7 2 370 377 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Alpha‐linolenic acid astaxanthin krill oil flaxseed oil Omega‐3 Index omega‐3 long‐chain polyunsaturated fatty acids Veterinary medicine SF600-1100 |
spellingShingle |
Alpha‐linolenic acid astaxanthin krill oil flaxseed oil Omega‐3 Index omega‐3 long‐chain polyunsaturated fatty acids Veterinary medicine SF600-1100 Tonje E. Dominguez Kiranpreet Kaur Lena Burri Enhanced omega‐3 index after long‐ versus short‐chain omega‐3 fatty acid supplementation in dogs |
topic_facet |
Alpha‐linolenic acid astaxanthin krill oil flaxseed oil Omega‐3 Index omega‐3 long‐chain polyunsaturated fatty acids Veterinary medicine SF600-1100 |
description |
Abstract Background The Omega‐3 Index is a test that measures the amount of the long‐chain omega‐3 polyunsaturated fatty acids (n‐3 PUFAs), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in red blood cell membranes, which is expressed as a percentage of all fatty acids. However, alpha‐linolenic acid (ALA) from flaxseed oil, which is a short‐chain n‐3 PUFA, is often promoted in pet feed as a n‐3 source, implicitly assuming it is an effective precursor of EPA and DHA. Objective This study was aimed to compare the effect of supplementation with a plant‐based short‐chain n‐3 PUFA source (flaxseed oil, FSO) with a marine long‐chain n‐3 PUFA source (astaxanthin krill oil, AKO) to increase the Omega‐3 Index in dogs. Methods Ten adult Alaskan Huskies of both genders were supplemented daily with 1,155 mg of EPA/DHA from AKO, whereas another 10 dogs received 1,068 mg ALA from flaxseed oil for 6 weeks. Fatty acid and Omega‐3 Index measurements of the two groups were taken after 0, 3 and 6 weeks for comparison. Results The EPA and DHA concentrations increased significantly only in the dogs fed with AKO resulting in a significant increase in mean Omega‐3 Index, from 1.68% at baseline to 2.7% after 6 weeks of supplementation (p < .0001). On the contrary, both EPA and DHA concentrations decreased significantly in the dogs fed with FSO, which led to a significant decrease in mean Omega‐3 Index from 1.6% at baseline to 0.96% at study end (p < .0001). Conclusions The results showed that supplementation of AKO from Antarctic krill led to a significant increase in the Omega‐3 Index in comparison to FSO in dogs. This suggests that preformed marine EPA and DHA sources are needed in dog feeds, as the dietary requirements proposed by feed industry organizations are not met with conversion from short‐chain n‐3 fatty acids. |
format |
Article in Journal/Newspaper |
author |
Tonje E. Dominguez Kiranpreet Kaur Lena Burri |
author_facet |
Tonje E. Dominguez Kiranpreet Kaur Lena Burri |
author_sort |
Tonje E. Dominguez |
title |
Enhanced omega‐3 index after long‐ versus short‐chain omega‐3 fatty acid supplementation in dogs |
title_short |
Enhanced omega‐3 index after long‐ versus short‐chain omega‐3 fatty acid supplementation in dogs |
title_full |
Enhanced omega‐3 index after long‐ versus short‐chain omega‐3 fatty acid supplementation in dogs |
title_fullStr |
Enhanced omega‐3 index after long‐ versus short‐chain omega‐3 fatty acid supplementation in dogs |
title_full_unstemmed |
Enhanced omega‐3 index after long‐ versus short‐chain omega‐3 fatty acid supplementation in dogs |
title_sort |
enhanced omega‐3 index after long‐ versus short‐chain omega‐3 fatty acid supplementation in dogs |
publisher |
Wiley |
publishDate |
2021 |
url |
https://doi.org/10.1002/vms3.369 https://doaj.org/article/c831ec5cfc354585b5f0ef4d62525f82 |
geographic |
Antarctic |
geographic_facet |
Antarctic |
genre |
Antarc* Antarctic Antarctic Krill Huskies |
genre_facet |
Antarc* Antarctic Antarctic Krill Huskies |
op_source |
Veterinary Medicine and Science, Vol 7, Iss 2, Pp 370-377 (2021) |
op_relation |
https://doi.org/10.1002/vms3.369 https://doaj.org/toc/2053-1095 2053-1095 doi:10.1002/vms3.369 https://doaj.org/article/c831ec5cfc354585b5f0ef4d62525f82 |
op_doi |
https://doi.org/10.1002/vms3.369 |
container_title |
Veterinary Medicine and Science |
container_volume |
7 |
container_issue |
2 |
container_start_page |
370 |
op_container_end_page |
377 |
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1766255766364225536 |