Helicobacter pylori asociado a vasculitis complicada con lesiones ulcerosas en piel. Reporte de un caso

• Main Authors: Arocha Sandoval F, Roa R, Parra Quevedo K
• Format: Article in Journal/Newspaper
• Language: English; Spanish
• Published: Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales 2001
• Subjects: Helicobacter pylori; ulcer; skin; vasculitis; ulcera; cutánea; Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; Derecho; Izquierdo; Neri
• Online Access: https://doaj.org/article/c7ffd5d7733649f0add7cfd806c1f979

Abstract: A 16-year-old Caucasian female patient from the city of Maracaibo who became ill, in November of 1999, presenting common eritomatosic lesions in the left ankle increasing in size and ulcerated, later presented similar lesions and characteristics in the right ankle, and in February of 2000 visited a dermatologist who indicated a treatment with topical and oral steroids. A biopsy was performed of the ulcerous lesion reporting vasculitis with necrosis fibrinoide. The patient does not respond to treatment and the treatment is stopped. A test of immune serological gave negative results. The antibodies IgM anti- Helicobacter pylori however are positive, indicating treatment with Metronidazol and Clarithromycin which is realized for a week. Results are positive with the disappearance of the ulcerous lesions. The relationship between H. Pylori and skin lesions in patients has been reported by other authors. Neri and Col associated with prurogo nodularis while Mozrzymas and Col found antibodies against H. pylori in patients with Henoch Scholein Purple. In both cases there was improvement with antibiotic treatment. In conclusion, H. pylori should be discarded as the agent responsible for the immunology phenomena such as vasculitis when we find immunology illnesses without apparent explanation. Resumen: Paciente femenina de 16 años de raza blanca y procedente de la ciudad de Maracaibo que inicia su enfermedad actual, en Noviembre de 1999 presentando lesiones papulares eritematosas en tobillo izquierdo, que aumentan de tama ño y se ulceran, posteriormente aparecen en tobillo derecho con similares características, en febrero del 2000 acude a medico dermatólogo quien indica tratamiento con esteroide tópico y oral, se practica biopsia de lesión ulcerosa, que reporta vasculitis con necrosis fibrinoide. La paciente no presenta mejoría por lo que se decide suspender tratamiento y realizar pruebas inmunoserológicas las cuales resultan negativas, sin embargo los anticuerpos IgM anti-Helicobacter pylori resultan positivos, ...