Longitudinal study of Plasmodium falciparum and Plasmodium vivax in a Karen population in Thailand
Abstract Background Clinical case treatment of malaria infections where Plasmodium falciparum and Plasmodium vivax are sympatric has achieved effective reductions in P. falciparum prevalence and incidence rates, but has been less successful for P. vivax . The high transmissibility of P. vivax and it...
Published in: | Malaria Journal |
---|---|
Main Authors: | , , , , , , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
BMC
2008
|
Subjects: | |
Online Access: | https://doi.org/10.1186/1475-2875-7-99 https://doaj.org/article/c7e8c058cb4d46cfbdc26b4a7b250474 |
id |
ftdoajarticles:oai:doaj.org/article:c7e8c058cb4d46cfbdc26b4a7b250474 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:c7e8c058cb4d46cfbdc26b4a7b250474 2023-05-15T15:11:26+02:00 Longitudinal study of Plasmodium falciparum and Plasmodium vivax in a Karen population in Thailand Blanc Herve Chavez Irwin F Chaimungkun Wutthichai Sornklom Samarn Prommongkol Sutthiporn Maneeboonyang Wanchai Thanyavanich Nipon Puangsa-art Supalarp Yimsamran Surapon Paul Richard E Phimpraphi Waraphon Looareesuwan Sornchai Sakuntabhai Anavaj Singhasivanon Pratap 2008-06-01T00:00:00Z https://doi.org/10.1186/1475-2875-7-99 https://doaj.org/article/c7e8c058cb4d46cfbdc26b4a7b250474 EN eng BMC http://www.malariajournal.com/content/7/1/99 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-7-99 1475-2875 https://doaj.org/article/c7e8c058cb4d46cfbdc26b4a7b250474 Malaria Journal, Vol 7, Iss 1, p 99 (2008) Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2008 ftdoajarticles https://doi.org/10.1186/1475-2875-7-99 2022-12-31T08:36:27Z Abstract Background Clinical case treatment of malaria infections where Plasmodium falciparum and Plasmodium vivax are sympatric has achieved effective reductions in P. falciparum prevalence and incidence rates, but has been less successful for P. vivax . The high transmissibility of P. vivax and its capacity to relapse have been suggested to make it a harder parasite species to control. Methods A clinical malaria case treatment programme was carried out over a decade in a Karen community composed of seven hamlets on the Thai-Myanmar border. Results From 1994 to 2004, prevalence rates of both P. falciparum and P. vivax decreased by 70–90% in six of the seven study hamlets, but were unchanged in one hamlet. Overall, incidence rates decreased by 72% and 76% for P. falciparum and P. vivax respectively over the period 1999–2004. The age-incidence and prevalence curves suggested that P. vivax was more transmissible than P. falciparum despite a greater overall burden of infection with P. falciparum . Male gender was associated with increased risk of clinical presentation with either parasite species. Children (< 15 years old) had an increased risk of presenting with P. vivax but not P. falciparum . Conclusion There was a considerable reduction in incidence rates of both P. vivax and P. falciparum over a decade following implementation of a case treatment programme. The concern that intervention methods would inadvertently favour one species over another, or even lead to an increase in one parasite species, does not appear to be fulfilled in this case. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 7 1 99 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Blanc Herve Chavez Irwin F Chaimungkun Wutthichai Sornklom Samarn Prommongkol Sutthiporn Maneeboonyang Wanchai Thanyavanich Nipon Puangsa-art Supalarp Yimsamran Surapon Paul Richard E Phimpraphi Waraphon Looareesuwan Sornchai Sakuntabhai Anavaj Singhasivanon Pratap Longitudinal study of Plasmodium falciparum and Plasmodium vivax in a Karen population in Thailand |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background Clinical case treatment of malaria infections where Plasmodium falciparum and Plasmodium vivax are sympatric has achieved effective reductions in P. falciparum prevalence and incidence rates, but has been less successful for P. vivax . The high transmissibility of P. vivax and its capacity to relapse have been suggested to make it a harder parasite species to control. Methods A clinical malaria case treatment programme was carried out over a decade in a Karen community composed of seven hamlets on the Thai-Myanmar border. Results From 1994 to 2004, prevalence rates of both P. falciparum and P. vivax decreased by 70–90% in six of the seven study hamlets, but were unchanged in one hamlet. Overall, incidence rates decreased by 72% and 76% for P. falciparum and P. vivax respectively over the period 1999–2004. The age-incidence and prevalence curves suggested that P. vivax was more transmissible than P. falciparum despite a greater overall burden of infection with P. falciparum . Male gender was associated with increased risk of clinical presentation with either parasite species. Children (< 15 years old) had an increased risk of presenting with P. vivax but not P. falciparum . Conclusion There was a considerable reduction in incidence rates of both P. vivax and P. falciparum over a decade following implementation of a case treatment programme. The concern that intervention methods would inadvertently favour one species over another, or even lead to an increase in one parasite species, does not appear to be fulfilled in this case. |
format |
Article in Journal/Newspaper |
author |
Blanc Herve Chavez Irwin F Chaimungkun Wutthichai Sornklom Samarn Prommongkol Sutthiporn Maneeboonyang Wanchai Thanyavanich Nipon Puangsa-art Supalarp Yimsamran Surapon Paul Richard E Phimpraphi Waraphon Looareesuwan Sornchai Sakuntabhai Anavaj Singhasivanon Pratap |
author_facet |
Blanc Herve Chavez Irwin F Chaimungkun Wutthichai Sornklom Samarn Prommongkol Sutthiporn Maneeboonyang Wanchai Thanyavanich Nipon Puangsa-art Supalarp Yimsamran Surapon Paul Richard E Phimpraphi Waraphon Looareesuwan Sornchai Sakuntabhai Anavaj Singhasivanon Pratap |
author_sort |
Blanc Herve |
title |
Longitudinal study of Plasmodium falciparum and Plasmodium vivax in a Karen population in Thailand |
title_short |
Longitudinal study of Plasmodium falciparum and Plasmodium vivax in a Karen population in Thailand |
title_full |
Longitudinal study of Plasmodium falciparum and Plasmodium vivax in a Karen population in Thailand |
title_fullStr |
Longitudinal study of Plasmodium falciparum and Plasmodium vivax in a Karen population in Thailand |
title_full_unstemmed |
Longitudinal study of Plasmodium falciparum and Plasmodium vivax in a Karen population in Thailand |
title_sort |
longitudinal study of plasmodium falciparum and plasmodium vivax in a karen population in thailand |
publisher |
BMC |
publishDate |
2008 |
url |
https://doi.org/10.1186/1475-2875-7-99 https://doaj.org/article/c7e8c058cb4d46cfbdc26b4a7b250474 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 7, Iss 1, p 99 (2008) |
op_relation |
http://www.malariajournal.com/content/7/1/99 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-7-99 1475-2875 https://doaj.org/article/c7e8c058cb4d46cfbdc26b4a7b250474 |
op_doi |
https://doi.org/10.1186/1475-2875-7-99 |
container_title |
Malaria Journal |
container_volume |
7 |
container_issue |
1 |
container_start_page |
99 |
_version_ |
1766342288017981440 |