A semi-automated multiplex high-throughput assay for measuring IgG antibodies against Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) domains in small volumes of plasma

• Published in: Malaria Journal
• Main Authors: Jensen Anja TR, Lusingu John, Theander Thor G, Kurtis Jonathan, Cham Gerald KK, Turner Louise
• Format: Article in Journal/Newspaper
• Language: English
• Published: BMC 2008
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Infectious and parasitic diseases; RC109-216; Arctic; Rho; Hercules
• Online Access: https://doi.org/10.1186/1475-2875-7-108; https://doaj.org/article/c6bf9554a3b2417d88ba0c4419b3bdbc

Abstract Background The level of antibodies against PfEMP1 is routinely quantified by the conventional microtitre enzyme-linked immunosorbent assay (ELISA). However, ELISA only measures one analyte at a time and requires a relatively large plasma volume if the complete antibody profile of the sample...