Factors Associated with 5-Year Costs of Care among a Cohort of Alcohol Use Disorder Patients: A Bayesian Network Model
Objectives To examine the direct effects of risk factors associated with the 5-year costs of care in persons with alcohol use disorder (AUD) and to examine whether remission decreases the costs of care. Methods Based on Electronic Health Record data collected in the North Karelia region in Finland f...
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The Korean Society of Medical Informatics
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ftdoajarticles:oai:doaj.org/article:c68c7c8bd13c45469cffdfb9d8d2917b 2023-05-15T17:00:22+02:00 Factors Associated with 5-Year Costs of Care among a Cohort of Alcohol Use Disorder Patients: A Bayesian Network Model Elina Rautiainen Olli-Pekka Ryynänen Tiina Laatikainen Pekka Kekolahti 2020-04-01T00:00:00Z https://doi.org/10.4258/hir.2020.26.2.129 https://doaj.org/article/c68c7c8bd13c45469cffdfb9d8d2917b EN eng The Korean Society of Medical Informatics http://e-hir.org/upload/pdf/hir-2020-26-2-129.pdf https://doaj.org/toc/2093-3681 https://doaj.org/toc/2093-369X 2093-3681 2093-369X doi:10.4258/hir.2020.26.2.129 https://doaj.org/article/c68c7c8bd13c45469cffdfb9d8d2917b Healthcare Informatics Research, Vol 26, Iss 2, Pp 129-145 (2020) bayes theorem causality alcohol-related disorders health care costs costs and cost analysis Computer applications to medicine. Medical informatics R858-859.7 article 2020 ftdoajarticles https://doi.org/10.4258/hir.2020.26.2.129 2022-12-31T16:25:09Z Objectives To examine the direct effects of risk factors associated with the 5-year costs of care in persons with alcohol use disorder (AUD) and to examine whether remission decreases the costs of care. Methods Based on Electronic Health Record data collected in the North Karelia region in Finland from 2012 to 2016, we built a non-causal augmented naïve Bayesian (ANB) network model to examine the directional relationship between 16 risk factors and the costs of care for a random cohort of 363 AUD patients. Jouffe’s proprietary likelihood matching algorithm and van der Weele’s disjunctive confounder criteria (DCC) were used to calculate the direct effects of the variables, and sensitivity analysis with tornado diagrams and analysis maximizing/minimizing the total cost of care were conducted. Results The highest direct effect on the total cost of care was observed for a number of chronic conditions, indicating on average more than a €26,000 increase in the 5-year mean cost for individuals with multiple ICD-10 diagnoses compared to individuals with less than two chronic conditions. Remission had a decreasing effect on the total cost accumulation during the 5-year follow-up period; the percentage of the lowest cost quartile (42.9% vs. 23.9%) increased among remitters, and that of the highest cost quartile (10.71% vs. 26.27%) decreased compared with current drinkers. Conclusions The ANB model with application of DCC identified that remission has a favorable causal effect on the total cost accumulation. A high number of chronic conditions was the main contributor to excess cost of care, indicating that comorbidity is an essential mediator of cost accumulation in AUD patients. Article in Journal/Newspaper karelia* Directory of Open Access Journals: DOAJ Articles Healthcare Informatics Research 26 2 129 145 |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
bayes theorem causality alcohol-related disorders health care costs costs and cost analysis Computer applications to medicine. Medical informatics R858-859.7 |
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bayes theorem causality alcohol-related disorders health care costs costs and cost analysis Computer applications to medicine. Medical informatics R858-859.7 Elina Rautiainen Olli-Pekka Ryynänen Tiina Laatikainen Pekka Kekolahti Factors Associated with 5-Year Costs of Care among a Cohort of Alcohol Use Disorder Patients: A Bayesian Network Model |
topic_facet |
bayes theorem causality alcohol-related disorders health care costs costs and cost analysis Computer applications to medicine. Medical informatics R858-859.7 |
description |
Objectives To examine the direct effects of risk factors associated with the 5-year costs of care in persons with alcohol use disorder (AUD) and to examine whether remission decreases the costs of care. Methods Based on Electronic Health Record data collected in the North Karelia region in Finland from 2012 to 2016, we built a non-causal augmented naïve Bayesian (ANB) network model to examine the directional relationship between 16 risk factors and the costs of care for a random cohort of 363 AUD patients. Jouffe’s proprietary likelihood matching algorithm and van der Weele’s disjunctive confounder criteria (DCC) were used to calculate the direct effects of the variables, and sensitivity analysis with tornado diagrams and analysis maximizing/minimizing the total cost of care were conducted. Results The highest direct effect on the total cost of care was observed for a number of chronic conditions, indicating on average more than a €26,000 increase in the 5-year mean cost for individuals with multiple ICD-10 diagnoses compared to individuals with less than two chronic conditions. Remission had a decreasing effect on the total cost accumulation during the 5-year follow-up period; the percentage of the lowest cost quartile (42.9% vs. 23.9%) increased among remitters, and that of the highest cost quartile (10.71% vs. 26.27%) decreased compared with current drinkers. Conclusions The ANB model with application of DCC identified that remission has a favorable causal effect on the total cost accumulation. A high number of chronic conditions was the main contributor to excess cost of care, indicating that comorbidity is an essential mediator of cost accumulation in AUD patients. |
format |
Article in Journal/Newspaper |
author |
Elina Rautiainen Olli-Pekka Ryynänen Tiina Laatikainen Pekka Kekolahti |
author_facet |
Elina Rautiainen Olli-Pekka Ryynänen Tiina Laatikainen Pekka Kekolahti |
author_sort |
Elina Rautiainen |
title |
Factors Associated with 5-Year Costs of Care among a Cohort of Alcohol Use Disorder Patients: A Bayesian Network Model |
title_short |
Factors Associated with 5-Year Costs of Care among a Cohort of Alcohol Use Disorder Patients: A Bayesian Network Model |
title_full |
Factors Associated with 5-Year Costs of Care among a Cohort of Alcohol Use Disorder Patients: A Bayesian Network Model |
title_fullStr |
Factors Associated with 5-Year Costs of Care among a Cohort of Alcohol Use Disorder Patients: A Bayesian Network Model |
title_full_unstemmed |
Factors Associated with 5-Year Costs of Care among a Cohort of Alcohol Use Disorder Patients: A Bayesian Network Model |
title_sort |
factors associated with 5-year costs of care among a cohort of alcohol use disorder patients: a bayesian network model |
publisher |
The Korean Society of Medical Informatics |
publishDate |
2020 |
url |
https://doi.org/10.4258/hir.2020.26.2.129 https://doaj.org/article/c68c7c8bd13c45469cffdfb9d8d2917b |
genre |
karelia* |
genre_facet |
karelia* |
op_source |
Healthcare Informatics Research, Vol 26, Iss 2, Pp 129-145 (2020) |
op_relation |
http://e-hir.org/upload/pdf/hir-2020-26-2-129.pdf https://doaj.org/toc/2093-3681 https://doaj.org/toc/2093-369X 2093-3681 2093-369X doi:10.4258/hir.2020.26.2.129 https://doaj.org/article/c68c7c8bd13c45469cffdfb9d8d2917b |
op_doi |
https://doi.org/10.4258/hir.2020.26.2.129 |
container_title |
Healthcare Informatics Research |
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26 |
container_issue |
2 |
container_start_page |
129 |
op_container_end_page |
145 |
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