Anopheline species composition and the 1014F-genotype in different ecological settings of Burkina Faso in relation to malaria transmission
Abstract Background A three-year longitudinal study was conducted in four sentinel sites from different ecological settings in Burkina Faso, between 2008 and 2010 to identify longitudinal changes in insecticide resistance within Anopheles gambiae complex species based on larval collection. During th...
Published in: | Malaria Journal |
---|---|
Main Authors: | , , , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
BMC
2019
|
Subjects: | |
Online Access: | https://doi.org/10.1186/s12936-019-2789-8 https://doaj.org/article/c61da37b57a84ff2b79e1b0194975931 |
id |
ftdoajarticles:oai:doaj.org/article:c61da37b57a84ff2b79e1b0194975931 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:c61da37b57a84ff2b79e1b0194975931 2023-05-15T15:16:19+02:00 Anopheline species composition and the 1014F-genotype in different ecological settings of Burkina Faso in relation to malaria transmission Alphonse Traoré Athanase Badolo Moussa W. Guelbeogo Antoine Sanou Mafalda Viana Luca Nelli Soumanaba Zongo Hyacinthe K. Toé Alfred S. Traoré Hilary Ranson N’Falé Sagnon 2019-05-01T00:00:00Z https://doi.org/10.1186/s12936-019-2789-8 https://doaj.org/article/c61da37b57a84ff2b79e1b0194975931 EN eng BMC http://link.springer.com/article/10.1186/s12936-019-2789-8 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-019-2789-8 1475-2875 https://doaj.org/article/c61da37b57a84ff2b79e1b0194975931 Malaria Journal, Vol 18, Iss 1, Pp 1-10 (2019) Malaria Diversity Anopheles gambiae Plasmodium falciparum kdr Insecticide Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2019 ftdoajarticles https://doi.org/10.1186/s12936-019-2789-8 2022-12-31T11:11:22Z Abstract Background A three-year longitudinal study was conducted in four sentinel sites from different ecological settings in Burkina Faso, between 2008 and 2010 to identify longitudinal changes in insecticide resistance within Anopheles gambiae complex species based on larval collection. During this study, adult mosquitoes were also collected indoor and outdoor using several methods of collection. The present study reports the diversity of malaria vectors and the 1014F-genotype from this adult collection and investigates the association between this 1014F-genotype and sporozoite rate. Methods Adult mosquitoes were collected from July to August (corresponding to the start of rainy season) and October to November (corresponding to the end of rainy season) over 3 years (2008–2010) at four sites across the country, using pyrethrum spray catches (PSC), exit traps and pit shelters. Anopheles gambiae complex mosquitoes were identified to species and genotyped for the L1014F kdr mutation by PCR using genomic DNA. The circumsporozoite antigen of Plasmodium falciparum was detected in mosquitoes using sandwich ELISA. Results Overall 9212 anopheline mosquitoes were collected during the study period. Of those, 6767 mosquitoes were identified as Anopheles gambiae sensu lato (s.l.). Anopheles arabiensis, Anopheles coluzzii, Anopheles gambiae and or Anopheles funestus were incriminated as vectors of P. falciparum in the study area with an average sporozoite rate of 5%, (95% CI 4.14–5.99%). The kdr1014F-genotype frequencies were 11.44% (95% CI 2.5–39.85%), 19.2% (95% CI 4.53–53.73%) and 89.9 (95% CI 63.14–97.45%), respectively for An. arabiensis, An. coluzzii and An. gambiae. The proportion of the 1014F-genotype varied between sporozoite-infected and uninfected An. gambiae s.l. group. There was no significant difference in the 1014F-genotype frequency between infected and uninfected mosquitoes. Conclusion The current study shows the diversity of malaria vectors and significant interaction between species composition and ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 18 1 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Malaria Diversity Anopheles gambiae Plasmodium falciparum kdr Insecticide Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
spellingShingle |
Malaria Diversity Anopheles gambiae Plasmodium falciparum kdr Insecticide Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Alphonse Traoré Athanase Badolo Moussa W. Guelbeogo Antoine Sanou Mafalda Viana Luca Nelli Soumanaba Zongo Hyacinthe K. Toé Alfred S. Traoré Hilary Ranson N’Falé Sagnon Anopheline species composition and the 1014F-genotype in different ecological settings of Burkina Faso in relation to malaria transmission |
topic_facet |
Malaria Diversity Anopheles gambiae Plasmodium falciparum kdr Insecticide Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background A three-year longitudinal study was conducted in four sentinel sites from different ecological settings in Burkina Faso, between 2008 and 2010 to identify longitudinal changes in insecticide resistance within Anopheles gambiae complex species based on larval collection. During this study, adult mosquitoes were also collected indoor and outdoor using several methods of collection. The present study reports the diversity of malaria vectors and the 1014F-genotype from this adult collection and investigates the association between this 1014F-genotype and sporozoite rate. Methods Adult mosquitoes were collected from July to August (corresponding to the start of rainy season) and October to November (corresponding to the end of rainy season) over 3 years (2008–2010) at four sites across the country, using pyrethrum spray catches (PSC), exit traps and pit shelters. Anopheles gambiae complex mosquitoes were identified to species and genotyped for the L1014F kdr mutation by PCR using genomic DNA. The circumsporozoite antigen of Plasmodium falciparum was detected in mosquitoes using sandwich ELISA. Results Overall 9212 anopheline mosquitoes were collected during the study period. Of those, 6767 mosquitoes were identified as Anopheles gambiae sensu lato (s.l.). Anopheles arabiensis, Anopheles coluzzii, Anopheles gambiae and or Anopheles funestus were incriminated as vectors of P. falciparum in the study area with an average sporozoite rate of 5%, (95% CI 4.14–5.99%). The kdr1014F-genotype frequencies were 11.44% (95% CI 2.5–39.85%), 19.2% (95% CI 4.53–53.73%) and 89.9 (95% CI 63.14–97.45%), respectively for An. arabiensis, An. coluzzii and An. gambiae. The proportion of the 1014F-genotype varied between sporozoite-infected and uninfected An. gambiae s.l. group. There was no significant difference in the 1014F-genotype frequency between infected and uninfected mosquitoes. Conclusion The current study shows the diversity of malaria vectors and significant interaction between species composition and ... |
format |
Article in Journal/Newspaper |
author |
Alphonse Traoré Athanase Badolo Moussa W. Guelbeogo Antoine Sanou Mafalda Viana Luca Nelli Soumanaba Zongo Hyacinthe K. Toé Alfred S. Traoré Hilary Ranson N’Falé Sagnon |
author_facet |
Alphonse Traoré Athanase Badolo Moussa W. Guelbeogo Antoine Sanou Mafalda Viana Luca Nelli Soumanaba Zongo Hyacinthe K. Toé Alfred S. Traoré Hilary Ranson N’Falé Sagnon |
author_sort |
Alphonse Traoré |
title |
Anopheline species composition and the 1014F-genotype in different ecological settings of Burkina Faso in relation to malaria transmission |
title_short |
Anopheline species composition and the 1014F-genotype in different ecological settings of Burkina Faso in relation to malaria transmission |
title_full |
Anopheline species composition and the 1014F-genotype in different ecological settings of Burkina Faso in relation to malaria transmission |
title_fullStr |
Anopheline species composition and the 1014F-genotype in different ecological settings of Burkina Faso in relation to malaria transmission |
title_full_unstemmed |
Anopheline species composition and the 1014F-genotype in different ecological settings of Burkina Faso in relation to malaria transmission |
title_sort |
anopheline species composition and the 1014f-genotype in different ecological settings of burkina faso in relation to malaria transmission |
publisher |
BMC |
publishDate |
2019 |
url |
https://doi.org/10.1186/s12936-019-2789-8 https://doaj.org/article/c61da37b57a84ff2b79e1b0194975931 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 18, Iss 1, Pp 1-10 (2019) |
op_relation |
http://link.springer.com/article/10.1186/s12936-019-2789-8 https://doaj.org/toc/1475-2875 doi:10.1186/s12936-019-2789-8 1475-2875 https://doaj.org/article/c61da37b57a84ff2b79e1b0194975931 |
op_doi |
https://doi.org/10.1186/s12936-019-2789-8 |
container_title |
Malaria Journal |
container_volume |
18 |
container_issue |
1 |
_version_ |
1766346611644956672 |