Efects of plasma corticosteroid concentration on the osmotic threshold for vasopressin releasing in Chagas' disease
The osmotic threshold for vasopressin release was studied in normal patients (n = 7) and in patients with the chronic form of Chagas'disease (n = 11). Positive correlation between osmotic threshold and plasma cortisol concentration was obtained for the Controls (y1 = 273,30 + 0,75x i; r = 0,78;...
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Sociedade Brasileira de Medicina Tropical (SBMT)
1983
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ftdoajarticles:oai:doaj.org/article:c60907a2aeab48a5b7131afa1b0efa23 2023-05-15T15:10:15+02:00 Efects of plasma corticosteroid concentration on the osmotic threshold for vasopressin releasing in Chagas' disease Tatsuto Kimachi Joel P. R. Veiga Euclydes C. Lima-Filho 1983-09-01T00:00:00Z https://doaj.org/article/c60907a2aeab48a5b7131afa1b0efa23 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821983000300003 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/c60907a2aeab48a5b7131afa1b0efa23 Revista da Sociedade Brasileira de Medicina Tropical, Vol 16, Iss 3, Pp 139-143 (1983) Concentração plasmática de cortisol Limiar osmótico Liberação de vasopressina Doença de Chagas crônica Plasma Cortisol Concentration Osmotic Threshold Vasopressin Release Chronic Chagas' Disease Arctic medicine. Tropical medicine RC955-962 article 1983 ftdoajarticles 2022-12-31T03:20:43Z The osmotic threshold for vasopressin release was studied in normal patients (n = 7) and in patients with the chronic form of Chagas'disease (n = 11). Positive correlation between osmotic threshold and plasma cortisol concentration was obtained for the Controls (y1 = 273,30 + 0,75x i; r = 0,78;P < 0,05), suggesting a modulating effect of cortisol on vasopressin release. The lack of correlation between the two parameters for the chronic chagasic patients was interpreted, on the basis of the general denervation associated with Chagas ' disease, to be the result of neuronal destruction in hypothalamic and/or extrahypothalamic centers related to the secretory control of vasopressin. O limiar osmótico para liberação da vaso- pressina foi estudado em pacientes normais (n = 7) e em pacientes com a forma crônica da moléstia de Chagas (n = 11). Verificou-se a existência de uma correlação positiva entre o limiar osmótico e a concentração plasmática do cortisol endógeno para os controles (y1 = 273,30 + 0,75 x i; r = 0,78, p < 0,05), sugerindo um efeito modulador do cortisol na liberação da vasopressina. A falta de correlação entre os dois parâmetros, para os pacientes chagásicos crônicos, interpretou-se, baseando-se na desnervação geral associada com a doença de Chagas, como sendo o resultado da destruição neuronal em centros hipotalâmicos ejou extra-hipotalâmicos relacionados com o controle secretário da vosopressina. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
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Directory of Open Access Journals: DOAJ Articles |
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English |
topic |
Concentração plasmática de cortisol Limiar osmótico Liberação de vasopressina Doença de Chagas crônica Plasma Cortisol Concentration Osmotic Threshold Vasopressin Release Chronic Chagas' Disease Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Concentração plasmática de cortisol Limiar osmótico Liberação de vasopressina Doença de Chagas crônica Plasma Cortisol Concentration Osmotic Threshold Vasopressin Release Chronic Chagas' Disease Arctic medicine. Tropical medicine RC955-962 Tatsuto Kimachi Joel P. R. Veiga Euclydes C. Lima-Filho Efects of plasma corticosteroid concentration on the osmotic threshold for vasopressin releasing in Chagas' disease |
topic_facet |
Concentração plasmática de cortisol Limiar osmótico Liberação de vasopressina Doença de Chagas crônica Plasma Cortisol Concentration Osmotic Threshold Vasopressin Release Chronic Chagas' Disease Arctic medicine. Tropical medicine RC955-962 |
description |
The osmotic threshold for vasopressin release was studied in normal patients (n = 7) and in patients with the chronic form of Chagas'disease (n = 11). Positive correlation between osmotic threshold and plasma cortisol concentration was obtained for the Controls (y1 = 273,30 + 0,75x i; r = 0,78;P < 0,05), suggesting a modulating effect of cortisol on vasopressin release. The lack of correlation between the two parameters for the chronic chagasic patients was interpreted, on the basis of the general denervation associated with Chagas ' disease, to be the result of neuronal destruction in hypothalamic and/or extrahypothalamic centers related to the secretory control of vasopressin. O limiar osmótico para liberação da vaso- pressina foi estudado em pacientes normais (n = 7) e em pacientes com a forma crônica da moléstia de Chagas (n = 11). Verificou-se a existência de uma correlação positiva entre o limiar osmótico e a concentração plasmática do cortisol endógeno para os controles (y1 = 273,30 + 0,75 x i; r = 0,78, p < 0,05), sugerindo um efeito modulador do cortisol na liberação da vasopressina. A falta de correlação entre os dois parâmetros, para os pacientes chagásicos crônicos, interpretou-se, baseando-se na desnervação geral associada com a doença de Chagas, como sendo o resultado da destruição neuronal em centros hipotalâmicos ejou extra-hipotalâmicos relacionados com o controle secretário da vosopressina. |
format |
Article in Journal/Newspaper |
author |
Tatsuto Kimachi Joel P. R. Veiga Euclydes C. Lima-Filho |
author_facet |
Tatsuto Kimachi Joel P. R. Veiga Euclydes C. Lima-Filho |
author_sort |
Tatsuto Kimachi |
title |
Efects of plasma corticosteroid concentration on the osmotic threshold for vasopressin releasing in Chagas' disease |
title_short |
Efects of plasma corticosteroid concentration on the osmotic threshold for vasopressin releasing in Chagas' disease |
title_full |
Efects of plasma corticosteroid concentration on the osmotic threshold for vasopressin releasing in Chagas' disease |
title_fullStr |
Efects of plasma corticosteroid concentration on the osmotic threshold for vasopressin releasing in Chagas' disease |
title_full_unstemmed |
Efects of plasma corticosteroid concentration on the osmotic threshold for vasopressin releasing in Chagas' disease |
title_sort |
efects of plasma corticosteroid concentration on the osmotic threshold for vasopressin releasing in chagas' disease |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
1983 |
url |
https://doaj.org/article/c60907a2aeab48a5b7131afa1b0efa23 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 16, Iss 3, Pp 139-143 (1983) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821983000300003 https://doaj.org/toc/0037-8682 https://doaj.org/toc/1678-9849 0037-8682 1678-9849 https://doaj.org/article/c60907a2aeab48a5b7131afa1b0efa23 |
_version_ |
1766341300414578688 |