High levels of Zinc-α-2-Glycoprotein among Omani AIDS patients on combined antiretroviral therapy
To investigate the levels of zinc-α-2-glycoprotein (ZAG) among Omani AIDS patients receiving combined antiretroviral therapy (cART). Methods: A total of 80 Omani AIDS patients (45 males and 35 females), average age of 36 years, who were receiving cART at the Sultan Qaboos University Hospital (SQUH),...
Published in: | Asian Pacific Journal of Tropical Biomedicine |
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Wolters Kluwer Medknow Publications
2014
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Online Access: | https://doi.org/10.12980/APJTB.4.201414B126 https://doaj.org/article/c5ab1a12ea594ae3b4bf5031ca92ba2a |
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ftdoajarticles:oai:doaj.org/article:c5ab1a12ea594ae3b4bf5031ca92ba2a 2023-05-15T15:07:26+02:00 High levels of Zinc-α-2-Glycoprotein among Omani AIDS patients on combined antiretroviral therapy Sidgi Syed Anwer Hasson Mohammed Saeed Al-Balushi Muzna Hamed Al Yahmadi Juma Zaid Al-Busaidi Elias Antony Said Mohammed Shafeeq Othman Talal Abdullah Sallam Mohammed Ahmad Idris Ali Abdullah Al-Jabri 2014-08-01T00:00:00Z https://doi.org/10.12980/APJTB.4.201414B126 https://doaj.org/article/c5ab1a12ea594ae3b4bf5031ca92ba2a EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S2221169115300757 https://doaj.org/toc/2221-1691 2221-1691 doi:10.12980/APJTB.4.201414B126 https://doaj.org/article/c5ab1a12ea594ae3b4bf5031ca92ba2a Asian Pacific Journal of Tropical Biomedicine, Vol 4, Iss 8, Pp 610-613 (2014) Zinc-α-2-glycoprotein AIDS Patients Combined antiretroviral therapy Levels Oman Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2014 ftdoajarticles https://doi.org/10.12980/APJTB.4.201414B126 2022-12-31T13:42:33Z To investigate the levels of zinc-α-2-glycoprotein (ZAG) among Omani AIDS patients receiving combined antiretroviral therapy (cART). Methods: A total of 80 Omani AIDS patients (45 males and 35 females), average age of 36 years, who were receiving cART at the Sultan Qaboos University Hospital (SQUH), Muscat, Oman, were tested for the levels of ZAG. In addition, 80 healthy blood donors (46 males and 34 females), average age of 26 years, attending the SQUH Blood Bank, were tested in parallel as a control group. Measurement of the ZAG levels was performed using a competitive enzyme-linked immunosorbent assay and in accordance with the manufacturer's instructions. Results: The ZAG levels were found to be significantly higher among AIDS patients compared to the healthy individuals (P=0.033). A total of 56 (70%) of the AIDS patients were found to have higher levels of ZAG and 16 (20%) AIDS patients were found to have high ZAG levels, which are significantly (P>0.031) associated with weight loss. Conclusions: ZAG levels are high among Omani AIDS patients on cART and this necessitates the measurement of ZAG on routine basis, as it is associated with weight loss. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Sultan ENVELOPE(-55.317,-55.317,-61.150,-61.150) Asian Pacific Journal of Tropical Biomedicine 4 8 610 613 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Zinc-α-2-glycoprotein AIDS Patients Combined antiretroviral therapy Levels Oman Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
spellingShingle |
Zinc-α-2-glycoprotein AIDS Patients Combined antiretroviral therapy Levels Oman Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Sidgi Syed Anwer Hasson Mohammed Saeed Al-Balushi Muzna Hamed Al Yahmadi Juma Zaid Al-Busaidi Elias Antony Said Mohammed Shafeeq Othman Talal Abdullah Sallam Mohammed Ahmad Idris Ali Abdullah Al-Jabri High levels of Zinc-α-2-Glycoprotein among Omani AIDS patients on combined antiretroviral therapy |
topic_facet |
Zinc-α-2-glycoprotein AIDS Patients Combined antiretroviral therapy Levels Oman Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
To investigate the levels of zinc-α-2-glycoprotein (ZAG) among Omani AIDS patients receiving combined antiretroviral therapy (cART). Methods: A total of 80 Omani AIDS patients (45 males and 35 females), average age of 36 years, who were receiving cART at the Sultan Qaboos University Hospital (SQUH), Muscat, Oman, were tested for the levels of ZAG. In addition, 80 healthy blood donors (46 males and 34 females), average age of 26 years, attending the SQUH Blood Bank, were tested in parallel as a control group. Measurement of the ZAG levels was performed using a competitive enzyme-linked immunosorbent assay and in accordance with the manufacturer's instructions. Results: The ZAG levels were found to be significantly higher among AIDS patients compared to the healthy individuals (P=0.033). A total of 56 (70%) of the AIDS patients were found to have higher levels of ZAG and 16 (20%) AIDS patients were found to have high ZAG levels, which are significantly (P>0.031) associated with weight loss. Conclusions: ZAG levels are high among Omani AIDS patients on cART and this necessitates the measurement of ZAG on routine basis, as it is associated with weight loss. |
format |
Article in Journal/Newspaper |
author |
Sidgi Syed Anwer Hasson Mohammed Saeed Al-Balushi Muzna Hamed Al Yahmadi Juma Zaid Al-Busaidi Elias Antony Said Mohammed Shafeeq Othman Talal Abdullah Sallam Mohammed Ahmad Idris Ali Abdullah Al-Jabri |
author_facet |
Sidgi Syed Anwer Hasson Mohammed Saeed Al-Balushi Muzna Hamed Al Yahmadi Juma Zaid Al-Busaidi Elias Antony Said Mohammed Shafeeq Othman Talal Abdullah Sallam Mohammed Ahmad Idris Ali Abdullah Al-Jabri |
author_sort |
Sidgi Syed Anwer Hasson |
title |
High levels of Zinc-α-2-Glycoprotein among Omani AIDS patients on combined antiretroviral therapy |
title_short |
High levels of Zinc-α-2-Glycoprotein among Omani AIDS patients on combined antiretroviral therapy |
title_full |
High levels of Zinc-α-2-Glycoprotein among Omani AIDS patients on combined antiretroviral therapy |
title_fullStr |
High levels of Zinc-α-2-Glycoprotein among Omani AIDS patients on combined antiretroviral therapy |
title_full_unstemmed |
High levels of Zinc-α-2-Glycoprotein among Omani AIDS patients on combined antiretroviral therapy |
title_sort |
high levels of zinc-α-2-glycoprotein among omani aids patients on combined antiretroviral therapy |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2014 |
url |
https://doi.org/10.12980/APJTB.4.201414B126 https://doaj.org/article/c5ab1a12ea594ae3b4bf5031ca92ba2a |
long_lat |
ENVELOPE(-55.317,-55.317,-61.150,-61.150) |
geographic |
Arctic Sultan |
geographic_facet |
Arctic Sultan |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 4, Iss 8, Pp 610-613 (2014) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2221169115300757 https://doaj.org/toc/2221-1691 2221-1691 doi:10.12980/APJTB.4.201414B126 https://doaj.org/article/c5ab1a12ea594ae3b4bf5031ca92ba2a |
op_doi |
https://doi.org/10.12980/APJTB.4.201414B126 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
4 |
container_issue |
8 |
container_start_page |
610 |
op_container_end_page |
613 |
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1766338936891768832 |