Hantavirus pulmonary syndrome in Santa Cruz, Bolivia: outbreak investigation and antibody prevalence study.
We report the results of an investigation of a small outbreak of hantavirus pulmonary syndrome in 2002 in the Department of Santa Cruz, Bolivia, where the disease had not previously been reported. Two cases were initially reported. The first case was a physician infected with Laguna Negra virus duri...
Published in: | PLoS Neglected Tropical Diseases |
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ftdoajarticles:oai:doaj.org/article:c46a4dad0d1e4b88b091da1b9b7a9f08 2023-05-15T15:08:59+02:00 Hantavirus pulmonary syndrome in Santa Cruz, Bolivia: outbreak investigation and antibody prevalence study. Joel M Montgomery Patrick J Blair Darin S Carroll James N Mills Alberto Gianella Naomi Iihoshi Ana M Briggiler Vidal Felices Milagros Salazar James G Olson Raisa A Glabman Daniel G Bausch 2012-01-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0001840 https://doaj.org/article/c46a4dad0d1e4b88b091da1b9b7a9f08 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC3475674?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0001840 https://doaj.org/article/c46a4dad0d1e4b88b091da1b9b7a9f08 PLoS Neglected Tropical Diseases, Vol 6, Iss 10, p e1840 (2012) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2012 ftdoajarticles https://doi.org/10.1371/journal.pntd.0001840 2022-12-31T10:05:43Z We report the results of an investigation of a small outbreak of hantavirus pulmonary syndrome in 2002 in the Department of Santa Cruz, Bolivia, where the disease had not previously been reported. Two cases were initially reported. The first case was a physician infected with Laguna Negra virus during a weekend visit to his ranch. Four other persons living on the ranch were IgM antibody-positive, two of whom were symptomatic for mild hantavirus pulmonary syndrome. The second case was a migrant sugarcane worker. Although no sample remained to determine the specific infecting hantavirus, a virus 90% homologous with Río Mamoré virus was previously found in small-eared pygmy rice rats (Oligoryzomys microtis) trapped in the area. An antibody prevalence study conducted in the region as part of the outbreak investigation showed 45 (9.1%) of 494 persons to be IgG positive, illustrating that hantavirus infection is common in Santa Cruz Department. Precipitation in the months preceding the outbreak was particularly heavy in comparison to other years, suggesting a possible climatic or ecological influence on rodent populations and risk of hantavirus transmission to humans. Hantavirus infection appears to be common in the Santa Cruz Department, but more comprehensive surveillance and field studies are needed to fully understand the epidemiology and risk to humans. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLoS Neglected Tropical Diseases 6 10 e1840 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Joel M Montgomery Patrick J Blair Darin S Carroll James N Mills Alberto Gianella Naomi Iihoshi Ana M Briggiler Vidal Felices Milagros Salazar James G Olson Raisa A Glabman Daniel G Bausch Hantavirus pulmonary syndrome in Santa Cruz, Bolivia: outbreak investigation and antibody prevalence study. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
We report the results of an investigation of a small outbreak of hantavirus pulmonary syndrome in 2002 in the Department of Santa Cruz, Bolivia, where the disease had not previously been reported. Two cases were initially reported. The first case was a physician infected with Laguna Negra virus during a weekend visit to his ranch. Four other persons living on the ranch were IgM antibody-positive, two of whom were symptomatic for mild hantavirus pulmonary syndrome. The second case was a migrant sugarcane worker. Although no sample remained to determine the specific infecting hantavirus, a virus 90% homologous with Río Mamoré virus was previously found in small-eared pygmy rice rats (Oligoryzomys microtis) trapped in the area. An antibody prevalence study conducted in the region as part of the outbreak investigation showed 45 (9.1%) of 494 persons to be IgG positive, illustrating that hantavirus infection is common in Santa Cruz Department. Precipitation in the months preceding the outbreak was particularly heavy in comparison to other years, suggesting a possible climatic or ecological influence on rodent populations and risk of hantavirus transmission to humans. Hantavirus infection appears to be common in the Santa Cruz Department, but more comprehensive surveillance and field studies are needed to fully understand the epidemiology and risk to humans. |
format |
Article in Journal/Newspaper |
author |
Joel M Montgomery Patrick J Blair Darin S Carroll James N Mills Alberto Gianella Naomi Iihoshi Ana M Briggiler Vidal Felices Milagros Salazar James G Olson Raisa A Glabman Daniel G Bausch |
author_facet |
Joel M Montgomery Patrick J Blair Darin S Carroll James N Mills Alberto Gianella Naomi Iihoshi Ana M Briggiler Vidal Felices Milagros Salazar James G Olson Raisa A Glabman Daniel G Bausch |
author_sort |
Joel M Montgomery |
title |
Hantavirus pulmonary syndrome in Santa Cruz, Bolivia: outbreak investigation and antibody prevalence study. |
title_short |
Hantavirus pulmonary syndrome in Santa Cruz, Bolivia: outbreak investigation and antibody prevalence study. |
title_full |
Hantavirus pulmonary syndrome in Santa Cruz, Bolivia: outbreak investigation and antibody prevalence study. |
title_fullStr |
Hantavirus pulmonary syndrome in Santa Cruz, Bolivia: outbreak investigation and antibody prevalence study. |
title_full_unstemmed |
Hantavirus pulmonary syndrome in Santa Cruz, Bolivia: outbreak investigation and antibody prevalence study. |
title_sort |
hantavirus pulmonary syndrome in santa cruz, bolivia: outbreak investigation and antibody prevalence study. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2012 |
url |
https://doi.org/10.1371/journal.pntd.0001840 https://doaj.org/article/c46a4dad0d1e4b88b091da1b9b7a9f08 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 6, Iss 10, p e1840 (2012) |
op_relation |
http://europepmc.org/articles/PMC3475674?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0001840 https://doaj.org/article/c46a4dad0d1e4b88b091da1b9b7a9f08 |
op_doi |
https://doi.org/10.1371/journal.pntd.0001840 |
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PLoS Neglected Tropical Diseases |
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6 |
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10 |
container_start_page |
e1840 |
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