Effects of malaria volunteer training on coverage and timeliness of diagnosis: a cluster randomized controlled trial in Myanmar
Abstract Background The use of community volunteers is expected to improve access to accurate diagnosis and timely treatment of malaria, using rapid diagnostic test (RDT) and artemisinin-based combination therapy (ACT). However, empirical data from the field are still limited. The aim of this study...
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ftdoajarticles:oai:doaj.org/article:c3cb5a0155044febbad69982b69fba55 2023-05-15T15:18:49+02:00 Effects of malaria volunteer training on coverage and timeliness of diagnosis: a cluster randomized controlled trial in Myanmar Ohnmar Tun-Min San-Shwe Than-Win Chongsuvivatwong Virasakdi 2012-09-01T00:00:00Z https://doi.org/10.1186/1475-2875-11-309 https://doaj.org/article/c3cb5a0155044febbad69982b69fba55 EN eng BMC http://www.malariajournal.com/content/11/1/309 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-11-309 1475-2875 https://doaj.org/article/c3cb5a0155044febbad69982b69fba55 Malaria Journal, Vol 11, Iss 1, p 309 (2012) Fever Malaria Early diagnosis Artemisinin-based combination therapy Volunteer workers Mortality Myanmar Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2012 ftdoajarticles https://doi.org/10.1186/1475-2875-11-309 2022-12-31T04:58:23Z Abstract Background The use of community volunteers is expected to improve access to accurate diagnosis and timely treatment of malaria, using rapid diagnostic test (RDT) and artemisinin-based combination therapy (ACT). However, empirical data from the field are still limited. The aim of this study was to assess whether training village volunteers on the use of Paracheck-Pf ® RDT and ACT (artemether-lumefantrine (AL)) for Plasmodium falciparum and presumptive treatment with chloroquine for Plasmodium vivax had an effect on the coverage of timely diagnosis and treatment and on mortality in malaria-endemic villages without health staff in Myanmar. Methods The study was designed as a cluster randomized controlled trial with a cross-sectional survey at baseline, a monthly visit for six months following the intervention (village volunteers trained and equipped with Paracheck-Pf ® ) and an endline survey at six months follow-up. Survey data were supplemented by the analysis of logbooks and field-based verbal autopsies. Villages with midwives (MW) in post were used as a third comparison group in the endline survey. Intention-to-treat analysis was used. Results Of 38 villages selected, 21 were randomly assigned to the intervention (two villages failed to participate) and 17 to the comparison group. The two groups had comparable baseline statistics. The blood tests provided by volunteers every month declined over time from 279 tests to 41 but not in MW group in 18 villages (from 326 to 180). In the endline survey, among interviewed subjects (268 intervention, 287 in comparison, 313 in MW), the coverage of RDT was low in all groups (14.9%, SE 2.4% in intervention; 5.7%, SE 1.7% in comparison; 21.4%, SE 2.6% in MW) although the intervention (OR 3.2, 95% CI 1.5-6.7) and MW (OR 5.4, 95% CI 2.6-11.0) were more likely to receive a blood test. Mean (SE) of blood tests after onset of fever in days was delayed (intervention 3.6 (0.3); comparison 4.8 (1.3); MW 3.2 (0.4)). Malaria mortality rates per 100,000 populations in a year ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 11 1 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English |
topic |
Fever Malaria Early diagnosis Artemisinin-based combination therapy Volunteer workers Mortality Myanmar Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Fever Malaria Early diagnosis Artemisinin-based combination therapy Volunteer workers Mortality Myanmar Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Ohnmar Tun-Min San-Shwe Than-Win Chongsuvivatwong Virasakdi Effects of malaria volunteer training on coverage and timeliness of diagnosis: a cluster randomized controlled trial in Myanmar |
topic_facet |
Fever Malaria Early diagnosis Artemisinin-based combination therapy Volunteer workers Mortality Myanmar Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background The use of community volunteers is expected to improve access to accurate diagnosis and timely treatment of malaria, using rapid diagnostic test (RDT) and artemisinin-based combination therapy (ACT). However, empirical data from the field are still limited. The aim of this study was to assess whether training village volunteers on the use of Paracheck-Pf ® RDT and ACT (artemether-lumefantrine (AL)) for Plasmodium falciparum and presumptive treatment with chloroquine for Plasmodium vivax had an effect on the coverage of timely diagnosis and treatment and on mortality in malaria-endemic villages without health staff in Myanmar. Methods The study was designed as a cluster randomized controlled trial with a cross-sectional survey at baseline, a monthly visit for six months following the intervention (village volunteers trained and equipped with Paracheck-Pf ® ) and an endline survey at six months follow-up. Survey data were supplemented by the analysis of logbooks and field-based verbal autopsies. Villages with midwives (MW) in post were used as a third comparison group in the endline survey. Intention-to-treat analysis was used. Results Of 38 villages selected, 21 were randomly assigned to the intervention (two villages failed to participate) and 17 to the comparison group. The two groups had comparable baseline statistics. The blood tests provided by volunteers every month declined over time from 279 tests to 41 but not in MW group in 18 villages (from 326 to 180). In the endline survey, among interviewed subjects (268 intervention, 287 in comparison, 313 in MW), the coverage of RDT was low in all groups (14.9%, SE 2.4% in intervention; 5.7%, SE 1.7% in comparison; 21.4%, SE 2.6% in MW) although the intervention (OR 3.2, 95% CI 1.5-6.7) and MW (OR 5.4, 95% CI 2.6-11.0) were more likely to receive a blood test. Mean (SE) of blood tests after onset of fever in days was delayed (intervention 3.6 (0.3); comparison 4.8 (1.3); MW 3.2 (0.4)). Malaria mortality rates per 100,000 populations in a year ... |
format |
Article in Journal/Newspaper |
author |
Ohnmar Tun-Min San-Shwe Than-Win Chongsuvivatwong Virasakdi |
author_facet |
Ohnmar Tun-Min San-Shwe Than-Win Chongsuvivatwong Virasakdi |
author_sort |
Ohnmar |
title |
Effects of malaria volunteer training on coverage and timeliness of diagnosis: a cluster randomized controlled trial in Myanmar |
title_short |
Effects of malaria volunteer training on coverage and timeliness of diagnosis: a cluster randomized controlled trial in Myanmar |
title_full |
Effects of malaria volunteer training on coverage and timeliness of diagnosis: a cluster randomized controlled trial in Myanmar |
title_fullStr |
Effects of malaria volunteer training on coverage and timeliness of diagnosis: a cluster randomized controlled trial in Myanmar |
title_full_unstemmed |
Effects of malaria volunteer training on coverage and timeliness of diagnosis: a cluster randomized controlled trial in Myanmar |
title_sort |
effects of malaria volunteer training on coverage and timeliness of diagnosis: a cluster randomized controlled trial in myanmar |
publisher |
BMC |
publishDate |
2012 |
url |
https://doi.org/10.1186/1475-2875-11-309 https://doaj.org/article/c3cb5a0155044febbad69982b69fba55 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 11, Iss 1, p 309 (2012) |
op_relation |
http://www.malariajournal.com/content/11/1/309 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-11-309 1475-2875 https://doaj.org/article/c3cb5a0155044febbad69982b69fba55 |
op_doi |
https://doi.org/10.1186/1475-2875-11-309 |
container_title |
Malaria Journal |
container_volume |
11 |
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1 |
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1766348994269675520 |