Hematological profile of COVID-19 infected children before and after the spread of the Omicron variant in Istanbul
Objective: To examine the effect of the COVID-19 virus, especially the Omicron variant, on hematological parameters of hospitalized pediatric patients during the COVID-19 pandemic. Methods: Medical records of pediatric COVID-19 patients hospitalized at Kartal Dr. Lütfi Kirdar City Hospital in Istanb...
Published in: | Asian Pacific Journal of Tropical Medicine |
---|---|
Main Authors: | , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2022
|
Subjects: | |
Online Access: | https://doi.org/10.4103/1995-7645.364004 https://doaj.org/article/c32b75bc411a45a5bee7db3ebd8a3806 |
id |
ftdoajarticles:oai:doaj.org/article:c32b75bc411a45a5bee7db3ebd8a3806 |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:c32b75bc411a45a5bee7db3ebd8a3806 2023-05-15T15:10:28+02:00 Hematological profile of COVID-19 infected children before and after the spread of the Omicron variant in Istanbul Berkin Berk Akbeyaz AyŞe Karaaslan Ceren Çetin Mehmet Tolga Köle Zeynep AltaŞ Yasemin Akın 2022-01-01T00:00:00Z https://doi.org/10.4103/1995-7645.364004 https://doaj.org/article/c32b75bc411a45a5bee7db3ebd8a3806 EN eng Wolters Kluwer Medknow Publications http://www.apjtm.org/article.asp?issn=1995-7645;year=2022;volume=15;issue=12;spage=551;epage=557;aulast=Akbeyaz https://doaj.org/toc/2352-4146 2352-4146 doi:10.4103/1995-7645.364004 https://doaj.org/article/c32b75bc411a45a5bee7db3ebd8a3806 Asian Pacific Journal of Tropical Medicine, Vol 15, Iss 12, Pp 551-557 (2022) covid children omicron hematologic findings Arctic medicine. Tropical medicine RC955-962 article 2022 ftdoajarticles https://doi.org/10.4103/1995-7645.364004 2023-01-15T01:25:47Z Objective: To examine the effect of the COVID-19 virus, especially the Omicron variant, on hematological parameters of hospitalized pediatric patients during the COVID-19 pandemic. Methods: Medical records of pediatric COVID-19 patients hospitalized at Kartal Dr. Lütfi Kirdar City Hospital in Istanbul, Turkey, between March 2020 and May 2022 were retrospectively reviewed to analyze data regarding demographics, SARS-CoV-2 infection polymerase chain reaction (PCR) test results, reverse-transcriptase (RT)-PCR for other respiratory agents, duration of hospital stay, and hematological and biochemical laboratory findings. Results: Out of 467 children with a confirmed diagnosis of SARS-CoV-2 infection, 94 (20.1%) had Omicron infection and 373 (79.9%) were infected with other variants; the Omicron group had younger patients than the remaining samples (P<0.001). The most frequent clinical symptoms in all children were cough (53.5%) and fever (32.3%), followed by vomiting (20.8%). Lung involvement in the Omicron group (10.6%) was significantly lower than in the remaining samples (29.8%) (P<0.001). Hemoglobin and lymphocyte levels were lower in the Omicron-infected group (both P<0.001), while prothrombin time, activated partial thromboplastin time, international normalized ratio, and D-dimer levels were significantly higher in this group (P<0.001, P<0.001, P<0.001, and P=0.023, respectively). In terms of lung involvement, those with lung involvement were significantly older (P<0.001). Conclusions: Although lung involvement was less common with Omicron infection, this group had greater hematological system involvement, such as anemia, lymphopenia, D-dimer elevation, and coagulation disorders. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Medicine 15 12 551 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
covid children omicron hematologic findings Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
covid children omicron hematologic findings Arctic medicine. Tropical medicine RC955-962 Berkin Berk Akbeyaz AyŞe Karaaslan Ceren Çetin Mehmet Tolga Köle Zeynep AltaŞ Yasemin Akın Hematological profile of COVID-19 infected children before and after the spread of the Omicron variant in Istanbul |
topic_facet |
covid children omicron hematologic findings Arctic medicine. Tropical medicine RC955-962 |
description |
Objective: To examine the effect of the COVID-19 virus, especially the Omicron variant, on hematological parameters of hospitalized pediatric patients during the COVID-19 pandemic. Methods: Medical records of pediatric COVID-19 patients hospitalized at Kartal Dr. Lütfi Kirdar City Hospital in Istanbul, Turkey, between March 2020 and May 2022 were retrospectively reviewed to analyze data regarding demographics, SARS-CoV-2 infection polymerase chain reaction (PCR) test results, reverse-transcriptase (RT)-PCR for other respiratory agents, duration of hospital stay, and hematological and biochemical laboratory findings. Results: Out of 467 children with a confirmed diagnosis of SARS-CoV-2 infection, 94 (20.1%) had Omicron infection and 373 (79.9%) were infected with other variants; the Omicron group had younger patients than the remaining samples (P<0.001). The most frequent clinical symptoms in all children were cough (53.5%) and fever (32.3%), followed by vomiting (20.8%). Lung involvement in the Omicron group (10.6%) was significantly lower than in the remaining samples (29.8%) (P<0.001). Hemoglobin and lymphocyte levels were lower in the Omicron-infected group (both P<0.001), while prothrombin time, activated partial thromboplastin time, international normalized ratio, and D-dimer levels were significantly higher in this group (P<0.001, P<0.001, P<0.001, and P=0.023, respectively). In terms of lung involvement, those with lung involvement were significantly older (P<0.001). Conclusions: Although lung involvement was less common with Omicron infection, this group had greater hematological system involvement, such as anemia, lymphopenia, D-dimer elevation, and coagulation disorders. |
format |
Article in Journal/Newspaper |
author |
Berkin Berk Akbeyaz AyŞe Karaaslan Ceren Çetin Mehmet Tolga Köle Zeynep AltaŞ Yasemin Akın |
author_facet |
Berkin Berk Akbeyaz AyŞe Karaaslan Ceren Çetin Mehmet Tolga Köle Zeynep AltaŞ Yasemin Akın |
author_sort |
Berkin Berk Akbeyaz |
title |
Hematological profile of COVID-19 infected children before and after the spread of the Omicron variant in Istanbul |
title_short |
Hematological profile of COVID-19 infected children before and after the spread of the Omicron variant in Istanbul |
title_full |
Hematological profile of COVID-19 infected children before and after the spread of the Omicron variant in Istanbul |
title_fullStr |
Hematological profile of COVID-19 infected children before and after the spread of the Omicron variant in Istanbul |
title_full_unstemmed |
Hematological profile of COVID-19 infected children before and after the spread of the Omicron variant in Istanbul |
title_sort |
hematological profile of covid-19 infected children before and after the spread of the omicron variant in istanbul |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2022 |
url |
https://doi.org/10.4103/1995-7645.364004 https://doaj.org/article/c32b75bc411a45a5bee7db3ebd8a3806 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Medicine, Vol 15, Iss 12, Pp 551-557 (2022) |
op_relation |
http://www.apjtm.org/article.asp?issn=1995-7645;year=2022;volume=15;issue=12;spage=551;epage=557;aulast=Akbeyaz https://doaj.org/toc/2352-4146 2352-4146 doi:10.4103/1995-7645.364004 https://doaj.org/article/c32b75bc411a45a5bee7db3ebd8a3806 |
op_doi |
https://doi.org/10.4103/1995-7645.364004 |
container_title |
Asian Pacific Journal of Tropical Medicine |
container_volume |
15 |
container_issue |
12 |
container_start_page |
551 |
_version_ |
1766341486425669632 |