Viral etiology of acute respiratory infections in children in Southern Iran

Abstract INTRODUCTION: Prevalence of influenza A virus (Flu-A), respiratory syncytial virus (RSV), and human metapneumovirus (hMPV) was assessed in children with acute respiratory infections (ARIs). METHODS: Nasopharyngeal aspirates and throat swabs were subjected to real-time polymerase chain react...

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Bibliographic Details
Published in:Revista da Sociedade Brasileira de Medicina Tropical
Main Authors: Mehrdad Halaji, Tayebeh Hashempour, Javad Moayedi, Gholam Reza Pouladfar, Behzad Khansarinejad, Reza Khashei, Afagh Moattari, Zahra Musavi, Farzaneh Ghassabi, Neda Pirbonyeh
Format: Article in Journal/Newspaper
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT)
Subjects:
Acute respiratory infections
Respiratory syncytial vírus
Influenza A vírus
Human metapneumovirus
Real-time polymerase chain reaction
Arctic medicine. Tropical medicine
RC955-962
Arctic
Aris
Online Access:https://doi.org/10.1590/0037-8682-0249-2018
https://doaj.org/article/c1b5d14a9dba46c89c40cd716d6b4c62
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Summary:Abstract INTRODUCTION: Prevalence of influenza A virus (Flu-A), respiratory syncytial virus (RSV), and human metapneumovirus (hMPV) was assessed in children with acute respiratory infections (ARIs). METHODS: Nasopharyngeal aspirates and throat swabs were subjected to real-time polymerase chain reaction (PCR) to detect RSV and Flu-A and to conventional PCR to detect hMPV. RESULTS: Of the 156 children assessed, 93 (59.6%) carried at least one virus, with 35.9% positive for RSV, 14.1% for hMPV, and 9.6% for Flu-A. The prevalence of co-infections was 2.6%. CONCLUSIONS: The high detection rate may reflect increased sensitivity of real-time PCR compared to traditional PCR and viral culture.

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