Coarse-resolution Ecology of Etiological Agent, Vector, and Reservoirs of Zoonotic Cutaneous Leishmaniasis in Libya.

Cutaneous leishmaniasis ranks among the tropical diseases least known and most neglected in Libya. World Health Organization reports recognized associations of Phlebotomus papatasi, Psammomys obesus, and Meriones spp., with transmission of zoonotic cutaneous leishmaniasis (ZCL; caused by Leishmania...

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Published in:PLOS Neglected Tropical Diseases
Main Authors: Abdallah M Samy, Badereddin B Annajar, Mostafa Ramadhan Dokhan, Samia Boussaa, A Townsend Peterson
Format: Article in Journal/Newspaper
Language:English
Published: Public Library of Science (PLoS) 2016
Subjects:
Online Access:https://doi.org/10.1371/journal.pntd.0004381
https://doaj.org/article/c16d2a50033347809668cb3fb4e13c27
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spelling ftdoajarticles:oai:doaj.org/article:c16d2a50033347809668cb3fb4e13c27 2023-05-15T15:08:14+02:00 Coarse-resolution Ecology of Etiological Agent, Vector, and Reservoirs of Zoonotic Cutaneous Leishmaniasis in Libya. Abdallah M Samy Badereddin B Annajar Mostafa Ramadhan Dokhan Samia Boussaa A Townsend Peterson 2016-02-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0004381 https://doaj.org/article/c16d2a50033347809668cb3fb4e13c27 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC4749236?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0004381 https://doaj.org/article/c16d2a50033347809668cb3fb4e13c27 PLoS Neglected Tropical Diseases, Vol 10, Iss 2, p e0004381 (2016) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2016 ftdoajarticles https://doi.org/10.1371/journal.pntd.0004381 2022-12-31T12:28:27Z Cutaneous leishmaniasis ranks among the tropical diseases least known and most neglected in Libya. World Health Organization reports recognized associations of Phlebotomus papatasi, Psammomys obesus, and Meriones spp., with transmission of zoonotic cutaneous leishmaniasis (ZCL; caused by Leishmania major) across Libya. Here, we map risk of ZCL infection based on occurrence records of L. major, P. papatasi, and four potential animal reservoirs (Meriones libycus, Meriones shawi, Psammomys obesus, and Gerbillus gerbillus). Ecological niche models identified limited risk areas for ZCL across the northern coast of the country; most species associated with ZCL transmission were confined to this same region, but some had ranges extending to central Libya. All ENM predictions were significant based on partial ROC tests. As a further evaluation of L. major ENM predictions, we compared predictions with 98 additional independent records provided by the Libyan National Centre for Disease Control (NCDC); all of these records fell inside the belt predicted as suitable for ZCL. We tested ecological niche similarity among vector, parasite, and reservoir species and could not reject any null hypotheses of niche similarity. Finally, we tested among possible combinations of vector and reservoir that could predict all recent human ZCL cases reported by NCDC; only three combinations could anticipate the distribution of human cases across the country. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 10 2 e0004381
institution Open Polar
collection Directory of Open Access Journals: DOAJ Articles
op_collection_id ftdoajarticles
language English
topic Arctic medicine. Tropical medicine
RC955-962
Public aspects of medicine
RA1-1270
spellingShingle Arctic medicine. Tropical medicine
RC955-962
Public aspects of medicine
RA1-1270
Abdallah M Samy
Badereddin B Annajar
Mostafa Ramadhan Dokhan
Samia Boussaa
A Townsend Peterson
Coarse-resolution Ecology of Etiological Agent, Vector, and Reservoirs of Zoonotic Cutaneous Leishmaniasis in Libya.
topic_facet Arctic medicine. Tropical medicine
RC955-962
Public aspects of medicine
RA1-1270
description Cutaneous leishmaniasis ranks among the tropical diseases least known and most neglected in Libya. World Health Organization reports recognized associations of Phlebotomus papatasi, Psammomys obesus, and Meriones spp., with transmission of zoonotic cutaneous leishmaniasis (ZCL; caused by Leishmania major) across Libya. Here, we map risk of ZCL infection based on occurrence records of L. major, P. papatasi, and four potential animal reservoirs (Meriones libycus, Meriones shawi, Psammomys obesus, and Gerbillus gerbillus). Ecological niche models identified limited risk areas for ZCL across the northern coast of the country; most species associated with ZCL transmission were confined to this same region, but some had ranges extending to central Libya. All ENM predictions were significant based on partial ROC tests. As a further evaluation of L. major ENM predictions, we compared predictions with 98 additional independent records provided by the Libyan National Centre for Disease Control (NCDC); all of these records fell inside the belt predicted as suitable for ZCL. We tested ecological niche similarity among vector, parasite, and reservoir species and could not reject any null hypotheses of niche similarity. Finally, we tested among possible combinations of vector and reservoir that could predict all recent human ZCL cases reported by NCDC; only three combinations could anticipate the distribution of human cases across the country.
format Article in Journal/Newspaper
author Abdallah M Samy
Badereddin B Annajar
Mostafa Ramadhan Dokhan
Samia Boussaa
A Townsend Peterson
author_facet Abdallah M Samy
Badereddin B Annajar
Mostafa Ramadhan Dokhan
Samia Boussaa
A Townsend Peterson
author_sort Abdallah M Samy
title Coarse-resolution Ecology of Etiological Agent, Vector, and Reservoirs of Zoonotic Cutaneous Leishmaniasis in Libya.
title_short Coarse-resolution Ecology of Etiological Agent, Vector, and Reservoirs of Zoonotic Cutaneous Leishmaniasis in Libya.
title_full Coarse-resolution Ecology of Etiological Agent, Vector, and Reservoirs of Zoonotic Cutaneous Leishmaniasis in Libya.
title_fullStr Coarse-resolution Ecology of Etiological Agent, Vector, and Reservoirs of Zoonotic Cutaneous Leishmaniasis in Libya.
title_full_unstemmed Coarse-resolution Ecology of Etiological Agent, Vector, and Reservoirs of Zoonotic Cutaneous Leishmaniasis in Libya.
title_sort coarse-resolution ecology of etiological agent, vector, and reservoirs of zoonotic cutaneous leishmaniasis in libya.
publisher Public Library of Science (PLoS)
publishDate 2016
url https://doi.org/10.1371/journal.pntd.0004381
https://doaj.org/article/c16d2a50033347809668cb3fb4e13c27
geographic Arctic
geographic_facet Arctic
genre Arctic
genre_facet Arctic
op_source PLoS Neglected Tropical Diseases, Vol 10, Iss 2, p e0004381 (2016)
op_relation http://europepmc.org/articles/PMC4749236?pdf=render
https://doaj.org/toc/1935-2727
https://doaj.org/toc/1935-2735
1935-2727
1935-2735
doi:10.1371/journal.pntd.0004381
https://doaj.org/article/c16d2a50033347809668cb3fb4e13c27
op_doi https://doi.org/10.1371/journal.pntd.0004381
container_title PLOS Neglected Tropical Diseases
container_volume 10
container_issue 2
container_start_page e0004381
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