Non-related contact lens coinfection with Acanthamoeba and Fusarium
Rationale: Microbial keratitis caused by coinfection with more than one species of pathogens is a severe condition with an unfavorable prognosis. Patient concerns: An immunocompetent Nepali woman complained of pain in the left eye, redness, watering and decreased vision for 5 months. Interventions:...
Published in: | Asian Pacific Journal of Tropical Medicine |
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ftdoajarticles:oai:doaj.org/article:c148a780a38648e29b167d63d359b450 2023-05-15T15:08:52+02:00 Non-related contact lens coinfection with Acanthamoeba and Fusarium Ranjit Sah Meenu Chaudhary Shusila Khadka Rafael Toledo Lucrecia Acosta 2019-01-01T00:00:00Z https://doi.org/10.4103/1995-7645.269909 https://doaj.org/article/c148a780a38648e29b167d63d359b450 EN eng Wolters Kluwer Medknow Publications http://www.apjtm.org/article.asp?issn=1995-7645;year=2019;volume=12;issue=10;spage=479;epage=482;aulast=Sah https://doaj.org/toc/2352-4146 2352-4146 doi:10.4103/1995-7645.269909 https://doaj.org/article/c148a780a38648e29b167d63d359b450 Asian Pacific Journal of Tropical Medicine, Vol 12, Iss 10, Pp 479-482 (2019) acanthamoeba fusarium coinfection microbial keratitis nepal Arctic medicine. Tropical medicine RC955-962 article 2019 ftdoajarticles https://doi.org/10.4103/1995-7645.269909 2022-12-31T11:01:17Z Rationale: Microbial keratitis caused by coinfection with more than one species of pathogens is a severe condition with an unfavorable prognosis. Patient concerns: An immunocompetent Nepali woman complained of pain in the left eye, redness, watering and decreased vision for 5 months. Interventions: The patient was discarded and accurately diagnosed with coinfection with Fusarium sp. and Acanthamoeba sp. The habit of washing the eyes with tap water from a domestic storage tank was the most likely source of infection since it was found to be contaminated with cysts of Acanthamoeba sp. The woman received eye drops of fluconazole and natamycin (5%), cefazoline (50 mg/mL), atropine, and tablets of itraconazole (100 mg), which were later switched to eye drops of clotrimazole (1%), natamycin (5%) and voriconazole (1%), and tablets of itraconazole. A full thickness penetrating keratoplasty was performed followed by treatment with eye drops of voriconazole (1%), natamet (5%), ofloxacin, atropine and carboxymethylcellulose for one week. Outcomes: After treatment, the condition of the patient significantly improved and was discharged one week after keratoplasty. Lessons: This is the first report of Acanthamoeba keratitis in Nepal and the first report of coinfection with Fusarium in this country and highlights the importance of early diagnosis of microbial keratitis both in single microorganism infections and coinfections, even in no contact lens wearers. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Medicine 12 10 479 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
acanthamoeba fusarium coinfection microbial keratitis nepal Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
acanthamoeba fusarium coinfection microbial keratitis nepal Arctic medicine. Tropical medicine RC955-962 Ranjit Sah Meenu Chaudhary Shusila Khadka Rafael Toledo Lucrecia Acosta Non-related contact lens coinfection with Acanthamoeba and Fusarium |
topic_facet |
acanthamoeba fusarium coinfection microbial keratitis nepal Arctic medicine. Tropical medicine RC955-962 |
description |
Rationale: Microbial keratitis caused by coinfection with more than one species of pathogens is a severe condition with an unfavorable prognosis. Patient concerns: An immunocompetent Nepali woman complained of pain in the left eye, redness, watering and decreased vision for 5 months. Interventions: The patient was discarded and accurately diagnosed with coinfection with Fusarium sp. and Acanthamoeba sp. The habit of washing the eyes with tap water from a domestic storage tank was the most likely source of infection since it was found to be contaminated with cysts of Acanthamoeba sp. The woman received eye drops of fluconazole and natamycin (5%), cefazoline (50 mg/mL), atropine, and tablets of itraconazole (100 mg), which were later switched to eye drops of clotrimazole (1%), natamycin (5%) and voriconazole (1%), and tablets of itraconazole. A full thickness penetrating keratoplasty was performed followed by treatment with eye drops of voriconazole (1%), natamet (5%), ofloxacin, atropine and carboxymethylcellulose for one week. Outcomes: After treatment, the condition of the patient significantly improved and was discharged one week after keratoplasty. Lessons: This is the first report of Acanthamoeba keratitis in Nepal and the first report of coinfection with Fusarium in this country and highlights the importance of early diagnosis of microbial keratitis both in single microorganism infections and coinfections, even in no contact lens wearers. |
format |
Article in Journal/Newspaper |
author |
Ranjit Sah Meenu Chaudhary Shusila Khadka Rafael Toledo Lucrecia Acosta |
author_facet |
Ranjit Sah Meenu Chaudhary Shusila Khadka Rafael Toledo Lucrecia Acosta |
author_sort |
Ranjit Sah |
title |
Non-related contact lens coinfection with Acanthamoeba and Fusarium |
title_short |
Non-related contact lens coinfection with Acanthamoeba and Fusarium |
title_full |
Non-related contact lens coinfection with Acanthamoeba and Fusarium |
title_fullStr |
Non-related contact lens coinfection with Acanthamoeba and Fusarium |
title_full_unstemmed |
Non-related contact lens coinfection with Acanthamoeba and Fusarium |
title_sort |
non-related contact lens coinfection with acanthamoeba and fusarium |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2019 |
url |
https://doi.org/10.4103/1995-7645.269909 https://doaj.org/article/c148a780a38648e29b167d63d359b450 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Medicine, Vol 12, Iss 10, Pp 479-482 (2019) |
op_relation |
http://www.apjtm.org/article.asp?issn=1995-7645;year=2019;volume=12;issue=10;spage=479;epage=482;aulast=Sah https://doaj.org/toc/2352-4146 2352-4146 doi:10.4103/1995-7645.269909 https://doaj.org/article/c148a780a38648e29b167d63d359b450 |
op_doi |
https://doi.org/10.4103/1995-7645.269909 |
container_title |
Asian Pacific Journal of Tropical Medicine |
container_volume |
12 |
container_issue |
10 |
container_start_page |
479 |
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1766340151355637760 |