Strongyloides stercoralis: Global Distribution and Risk Factors.
BACKGROUND: The soil-transmitted threadworm, Strongyloides stercoralis, is one of the most neglected among the so-called neglected tropical diseases (NTDs). We reviewed studies of the last 20 years on S. stercoralis's global prevalence in general populations and risk groups. METHODS/PRINCIPAL F...
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ftdoajarticles:oai:doaj.org/article:c077b9113b0f4dcc950c5321949167d7 2023-05-15T15:11:05+02:00 Strongyloides stercoralis: Global Distribution and Risk Factors. Fabian Schär Ulf Trostdorf Federica Giardina Virak Khieu Sinuon Muth Hanspeter Marti Penelope Vounatsou Peter Odermatt 2013-01-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0002288 https://doaj.org/article/c077b9113b0f4dcc950c5321949167d7 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC3708837?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0002288 https://doaj.org/article/c077b9113b0f4dcc950c5321949167d7 PLoS Neglected Tropical Diseases, Vol 7, Iss 7, p e2288 (2013) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2013 ftdoajarticles https://doi.org/10.1371/journal.pntd.0002288 2022-12-31T13:43:33Z BACKGROUND: The soil-transmitted threadworm, Strongyloides stercoralis, is one of the most neglected among the so-called neglected tropical diseases (NTDs). We reviewed studies of the last 20 years on S. stercoralis's global prevalence in general populations and risk groups. METHODS/PRINCIPAL FINDINGS: A literature search was performed in PubMed for articles published between January 1989 and October 2011. Articles presenting information on infection prevalence were included. A Bayesian meta-analysis was carried out to obtain country-specific prevalence estimates and to compare disease odds ratios in different risk groups taking into account the sensitivities of the diagnostic methods applied. A total of 354 studies from 78 countries were included for the prevalence calculations, 194 (62.4%) were community-based studies, 121 (34.2%) were hospital-based studies and 39 (11.0%) were studies on refugees and immigrants. World maps with country data are provided. In numerous African, Asian and South-American resource-poor countries, information on S. stercoralis is lacking. The meta-analysis showed an association between HIV-infection/alcoholism and S. stercoralis infection (OR: 2.17 BCI: 1.18-4.01; OR: 6.69; BCI: 1.47-33.8), respectively. CONCLUSIONS: Our findings show high infection prevalence rates in the general population in selected countries and geographical regions. S. stercoralis infection is prominent in several risk groups. Adequate information on the prevalence is still lacking from many countries. However, current information underscore that S. stercoralis must not be neglected. Further assessments in socio-economic and ecological settings are needed and integration into global helminth control is warranted. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLoS Neglected Tropical Diseases 7 7 e2288 |
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Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Fabian Schär Ulf Trostdorf Federica Giardina Virak Khieu Sinuon Muth Hanspeter Marti Penelope Vounatsou Peter Odermatt Strongyloides stercoralis: Global Distribution and Risk Factors. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
BACKGROUND: The soil-transmitted threadworm, Strongyloides stercoralis, is one of the most neglected among the so-called neglected tropical diseases (NTDs). We reviewed studies of the last 20 years on S. stercoralis's global prevalence in general populations and risk groups. METHODS/PRINCIPAL FINDINGS: A literature search was performed in PubMed for articles published between January 1989 and October 2011. Articles presenting information on infection prevalence were included. A Bayesian meta-analysis was carried out to obtain country-specific prevalence estimates and to compare disease odds ratios in different risk groups taking into account the sensitivities of the diagnostic methods applied. A total of 354 studies from 78 countries were included for the prevalence calculations, 194 (62.4%) were community-based studies, 121 (34.2%) were hospital-based studies and 39 (11.0%) were studies on refugees and immigrants. World maps with country data are provided. In numerous African, Asian and South-American resource-poor countries, information on S. stercoralis is lacking. The meta-analysis showed an association between HIV-infection/alcoholism and S. stercoralis infection (OR: 2.17 BCI: 1.18-4.01; OR: 6.69; BCI: 1.47-33.8), respectively. CONCLUSIONS: Our findings show high infection prevalence rates in the general population in selected countries and geographical regions. S. stercoralis infection is prominent in several risk groups. Adequate information on the prevalence is still lacking from many countries. However, current information underscore that S. stercoralis must not be neglected. Further assessments in socio-economic and ecological settings are needed and integration into global helminth control is warranted. |
format |
Article in Journal/Newspaper |
author |
Fabian Schär Ulf Trostdorf Federica Giardina Virak Khieu Sinuon Muth Hanspeter Marti Penelope Vounatsou Peter Odermatt |
author_facet |
Fabian Schär Ulf Trostdorf Federica Giardina Virak Khieu Sinuon Muth Hanspeter Marti Penelope Vounatsou Peter Odermatt |
author_sort |
Fabian Schär |
title |
Strongyloides stercoralis: Global Distribution and Risk Factors. |
title_short |
Strongyloides stercoralis: Global Distribution and Risk Factors. |
title_full |
Strongyloides stercoralis: Global Distribution and Risk Factors. |
title_fullStr |
Strongyloides stercoralis: Global Distribution and Risk Factors. |
title_full_unstemmed |
Strongyloides stercoralis: Global Distribution and Risk Factors. |
title_sort |
strongyloides stercoralis: global distribution and risk factors. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2013 |
url |
https://doi.org/10.1371/journal.pntd.0002288 https://doaj.org/article/c077b9113b0f4dcc950c5321949167d7 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 7, Iss 7, p e2288 (2013) |
op_relation |
http://europepmc.org/articles/PMC3708837?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0002288 https://doaj.org/article/c077b9113b0f4dcc950c5321949167d7 |
op_doi |
https://doi.org/10.1371/journal.pntd.0002288 |
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PLoS Neglected Tropical Diseases |
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7 |
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7 |
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e2288 |
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