Pam3CSK4 enhances adaptive immune responses to recombinant Mycobacterium bovis bacille Calmette-Guérin expressing Plasmodium falciparum C-terminus merozoite surface protein-1

• Published in: Asian Pacific Journal of Tropical Biomedicine
• Main Authors: Mohamed H Abdikarim, Muhammad A Abbas, Munirah N Zakaria, Robaiza Zakaria, Rapeah Suppian
• Format: Article in Journal/Newspaper
• Language: English
• Published: Wolters Kluwer Medknow Publications 2019
• Subjects: adjuvant rbcg; immune; msp-1; tlr-2; Arctic medicine. Tropical medicine; RC955-962; Biology (General); QH301-705.5; Arctic; Calmette
• Online Access: https://doi.org/10.4103/2221-1691.261742; https://doaj.org/article/c01e25e849e3428e8af8c3153a146cd4

Objective: To determine the effects of toll-like receptor 2 (TLR-2) agonist, Pam3CSK4, on cellular and humoral immune response against recombinant Mycobacterium bovis bacille Calmette-Guérin (rBCG) expressing the C-terminus of merozoite surface protein-1 of Plasmodium falciparum. Methods: Six groups...