Sweepstakes reproductive success via pervasive and recurrent selective sweeps
Highly fecund natural populations characterized by high early mortality abound, yet our knowledge about their recruitment dynamics is somewhat rudimentary. This knowledge gap has implications for our understanding of genetic variation, population connectivity, local adaptation, and the resilience of...
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eLife Sciences Publications Ltd
2023
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ftdoajarticles:oai:doaj.org/article:c00f55b07bd9432fb5d3da7739e95d8b 2023-05-15T15:27:18+02:00 Sweepstakes reproductive success via pervasive and recurrent selective sweeps Einar Árnason Jere Koskela Katrín Halldórsdóttir Bjarki Eldon 2023-02-01T00:00:00Z https://doi.org/10.7554/eLife.80781 https://doaj.org/article/c00f55b07bd9432fb5d3da7739e95d8b EN eng eLife Sciences Publications Ltd https://elifesciences.org/articles/80781 https://doaj.org/toc/2050-084X doi:10.7554/eLife.80781 2050-084X e80781 https://doaj.org/article/c00f55b07bd9432fb5d3da7739e95d8b eLife, Vol 12 (2023) reproductive sweepstakes selection recruitment dynamics multiple-merger coalescents selective sweeps Atlantic cod Medicine R Science Q Biology (General) QH301-705.5 article 2023 ftdoajarticles https://doi.org/10.7554/eLife.80781 2023-02-26T01:41:00Z Highly fecund natural populations characterized by high early mortality abound, yet our knowledge about their recruitment dynamics is somewhat rudimentary. This knowledge gap has implications for our understanding of genetic variation, population connectivity, local adaptation, and the resilience of highly fecund populations. The concept of sweepstakes reproductive success, which posits a considerable variance and skew in individual reproductive output, is key to understanding the distribution of individual reproductive success. However, it still needs to be determined whether highly fecund organisms reproduce through sweepstakes and, if they do, the relative roles of neutral and selective sweepstakes. Here, we use coalescent-based statistical analysis of population genomic data to show that selective sweepstakes likely explain recruitment dynamics in the highly fecund Atlantic cod. We show that the Kingman coalescent (modelling no sweepstakes) and the Xi-Beta coalescent (modelling random sweepstakes), including complex demography and background selection, do not provide an adequate fit for the data. The Durrett–Schweinsberg coalescent, in which selective sweepstakes result from recurrent and pervasive selective sweeps of new mutations, offers greater explanatory power. Our results show that models of sweepstakes reproduction and multiple-merger coalescents are relevant and necessary for understanding genetic diversity in highly fecund natural populations. These findings have fundamental implications for understanding the recruitment variation of fish stocks and general evolutionary genomics of high-fecundity organisms. Article in Journal/Newspaper atlantic cod Directory of Open Access Journals: DOAJ Articles eLife 12 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
reproductive sweepstakes selection recruitment dynamics multiple-merger coalescents selective sweeps Atlantic cod Medicine R Science Q Biology (General) QH301-705.5 |
spellingShingle |
reproductive sweepstakes selection recruitment dynamics multiple-merger coalescents selective sweeps Atlantic cod Medicine R Science Q Biology (General) QH301-705.5 Einar Árnason Jere Koskela Katrín Halldórsdóttir Bjarki Eldon Sweepstakes reproductive success via pervasive and recurrent selective sweeps |
topic_facet |
reproductive sweepstakes selection recruitment dynamics multiple-merger coalescents selective sweeps Atlantic cod Medicine R Science Q Biology (General) QH301-705.5 |
description |
Highly fecund natural populations characterized by high early mortality abound, yet our knowledge about their recruitment dynamics is somewhat rudimentary. This knowledge gap has implications for our understanding of genetic variation, population connectivity, local adaptation, and the resilience of highly fecund populations. The concept of sweepstakes reproductive success, which posits a considerable variance and skew in individual reproductive output, is key to understanding the distribution of individual reproductive success. However, it still needs to be determined whether highly fecund organisms reproduce through sweepstakes and, if they do, the relative roles of neutral and selective sweepstakes. Here, we use coalescent-based statistical analysis of population genomic data to show that selective sweepstakes likely explain recruitment dynamics in the highly fecund Atlantic cod. We show that the Kingman coalescent (modelling no sweepstakes) and the Xi-Beta coalescent (modelling random sweepstakes), including complex demography and background selection, do not provide an adequate fit for the data. The Durrett–Schweinsberg coalescent, in which selective sweepstakes result from recurrent and pervasive selective sweeps of new mutations, offers greater explanatory power. Our results show that models of sweepstakes reproduction and multiple-merger coalescents are relevant and necessary for understanding genetic diversity in highly fecund natural populations. These findings have fundamental implications for understanding the recruitment variation of fish stocks and general evolutionary genomics of high-fecundity organisms. |
format |
Article in Journal/Newspaper |
author |
Einar Árnason Jere Koskela Katrín Halldórsdóttir Bjarki Eldon |
author_facet |
Einar Árnason Jere Koskela Katrín Halldórsdóttir Bjarki Eldon |
author_sort |
Einar Árnason |
title |
Sweepstakes reproductive success via pervasive and recurrent selective sweeps |
title_short |
Sweepstakes reproductive success via pervasive and recurrent selective sweeps |
title_full |
Sweepstakes reproductive success via pervasive and recurrent selective sweeps |
title_fullStr |
Sweepstakes reproductive success via pervasive and recurrent selective sweeps |
title_full_unstemmed |
Sweepstakes reproductive success via pervasive and recurrent selective sweeps |
title_sort |
sweepstakes reproductive success via pervasive and recurrent selective sweeps |
publisher |
eLife Sciences Publications Ltd |
publishDate |
2023 |
url |
https://doi.org/10.7554/eLife.80781 https://doaj.org/article/c00f55b07bd9432fb5d3da7739e95d8b |
genre |
atlantic cod |
genre_facet |
atlantic cod |
op_source |
eLife, Vol 12 (2023) |
op_relation |
https://elifesciences.org/articles/80781 https://doaj.org/toc/2050-084X doi:10.7554/eLife.80781 2050-084X e80781 https://doaj.org/article/c00f55b07bd9432fb5d3da7739e95d8b |
op_doi |
https://doi.org/10.7554/eLife.80781 |
container_title |
eLife |
container_volume |
12 |
_version_ |
1766357747234766848 |