Prognostic value of plasma C-reactive protein in the evaluation of paraquat poisoning patients
Objective: To investigate the prognostic value of plasma C-reactive protein (CRP) level in patients with paraquat poisoning. Methods: This study included 162 patients with paraquat poisoning. The data of plasma paraquat, CRP level and arterial blood gas were analyzed. Cox regression analysis was app...
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Wolters Kluwer Medknow Publications
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ftdoajarticles:oai:doaj.org/article:bf957c230a24429a854bbef144287cf5 2023-05-15T15:09:04+02:00 Prognostic value of plasma C-reactive protein in the evaluation of paraquat poisoning patients Zong Ning Yu-Long Bai Hua Lu Kang-Lin Mo 2015-10-01T00:00:00Z https://doi.org/10.1016/j.apjtb.2015.06.011 https://doaj.org/article/bf957c230a24429a854bbef144287cf5 EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S2221169115001483 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2015.06.011 https://doaj.org/article/bf957c230a24429a854bbef144287cf5 Asian Pacific Journal of Tropical Biomedicine, Vol 5, Iss 10, Pp 841-844 (2015) Paraquat poisoning C-reactive protein Prognosis Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2015 ftdoajarticles https://doi.org/10.1016/j.apjtb.2015.06.011 2022-12-31T00:32:02Z Objective: To investigate the prognostic value of plasma C-reactive protein (CRP) level in patients with paraquat poisoning. Methods: This study included 162 patients with paraquat poisoning. The data of plasma paraquat, CRP level and arterial blood gas were analyzed. Cox regression analysis was applied to evaluate the risk factors of prognosis. Receiver operating characteristics curve analysis and area under curve were used to calculate the predictive power of significant variable. Differences in patient survival were determined using the Kaplan–Meier method and a log-rank test. Results: Plasma CRP level was significantly increased in non-survival patients compared with survival patients (P < 0.05), and positively correlated with plasma paraquat level (P < 0.05). Cox regression analysis revealed that plasma CRP level was an independent prognostic marker of mortality within 30 days. The receiver operating characteristics curve analysis indicated that area under curve of plasma CRP level was 0.867 (95% CI: 0.81–0.93), and the cut-off value was 18 mg/L, and patients with CRP level over this value had a poor survival time compared with those with less than this value. Conclusions: These results suggest that plasma CRP level is distinct increased in patients with paraquat poisoning, and the plasma CRP level may be useful for the prediction of prognosis in paraquat poisoning. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Meier ENVELOPE(-45.900,-45.900,-60.633,-60.633) Asian Pacific Journal of Tropical Biomedicine 5 10 841 844 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Paraquat poisoning C-reactive protein Prognosis Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
spellingShingle |
Paraquat poisoning C-reactive protein Prognosis Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Zong Ning Yu-Long Bai Hua Lu Kang-Lin Mo Prognostic value of plasma C-reactive protein in the evaluation of paraquat poisoning patients |
topic_facet |
Paraquat poisoning C-reactive protein Prognosis Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Objective: To investigate the prognostic value of plasma C-reactive protein (CRP) level in patients with paraquat poisoning. Methods: This study included 162 patients with paraquat poisoning. The data of plasma paraquat, CRP level and arterial blood gas were analyzed. Cox regression analysis was applied to evaluate the risk factors of prognosis. Receiver operating characteristics curve analysis and area under curve were used to calculate the predictive power of significant variable. Differences in patient survival were determined using the Kaplan–Meier method and a log-rank test. Results: Plasma CRP level was significantly increased in non-survival patients compared with survival patients (P < 0.05), and positively correlated with plasma paraquat level (P < 0.05). Cox regression analysis revealed that plasma CRP level was an independent prognostic marker of mortality within 30 days. The receiver operating characteristics curve analysis indicated that area under curve of plasma CRP level was 0.867 (95% CI: 0.81–0.93), and the cut-off value was 18 mg/L, and patients with CRP level over this value had a poor survival time compared with those with less than this value. Conclusions: These results suggest that plasma CRP level is distinct increased in patients with paraquat poisoning, and the plasma CRP level may be useful for the prediction of prognosis in paraquat poisoning. |
format |
Article in Journal/Newspaper |
author |
Zong Ning Yu-Long Bai Hua Lu Kang-Lin Mo |
author_facet |
Zong Ning Yu-Long Bai Hua Lu Kang-Lin Mo |
author_sort |
Zong Ning |
title |
Prognostic value of plasma C-reactive protein in the evaluation of paraquat poisoning patients |
title_short |
Prognostic value of plasma C-reactive protein in the evaluation of paraquat poisoning patients |
title_full |
Prognostic value of plasma C-reactive protein in the evaluation of paraquat poisoning patients |
title_fullStr |
Prognostic value of plasma C-reactive protein in the evaluation of paraquat poisoning patients |
title_full_unstemmed |
Prognostic value of plasma C-reactive protein in the evaluation of paraquat poisoning patients |
title_sort |
prognostic value of plasma c-reactive protein in the evaluation of paraquat poisoning patients |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2015 |
url |
https://doi.org/10.1016/j.apjtb.2015.06.011 https://doaj.org/article/bf957c230a24429a854bbef144287cf5 |
long_lat |
ENVELOPE(-45.900,-45.900,-60.633,-60.633) |
geographic |
Arctic Meier |
geographic_facet |
Arctic Meier |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 5, Iss 10, Pp 841-844 (2015) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2221169115001483 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/j.apjtb.2015.06.011 https://doaj.org/article/bf957c230a24429a854bbef144287cf5 |
op_doi |
https://doi.org/10.1016/j.apjtb.2015.06.011 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
5 |
container_issue |
10 |
container_start_page |
841 |
op_container_end_page |
844 |
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1766340296505819136 |