Meningeal cryptococcosis and SARS-CoV-2 infection in people living with HIV/AIDS
Introduction. Fungal infections in patients with COVID-19 was one of the most debated topics during the pandemic. Objectives. To analyze the clinical characteristics and evolution of people living with HIV/AIDS and coinfection with cryptococcus and COVID-19 (group A) or without it (group B). Materia...
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ftdoajarticles:oai:doaj.org/article:bf805caaa55f448a91adf50b5ca07aeb 2023-10-09T21:49:12+02:00 Meningeal cryptococcosis and SARS-CoV-2 infection in people living with HIV/AIDS Fernando Antonio Messina Andrés Benchetrit Andrea Bocassi María de las Mercedes Romero Sofía Bauer Emmanuel Marín Facundo Bertera Guillermo Onis Matías Enzenhofer Milagro Sánchez Lilia Mammana Dana Mijalovsky Gabriela Santiso 2023-08-01T00:00:00Z https://doi.org/10.7705/biomedica.6872 https://doaj.org/article/bf805caaa55f448a91adf50b5ca07aeb EN ES eng spa Instituto Nacional de Salud https://revistabiomedica.org/index.php/biomedica/article/view/6872 https://doaj.org/toc/0120-4157 0120-4157 doi:10.7705/biomedica.6872 https://doaj.org/article/bf805caaa55f448a91adf50b5ca07aeb Biomédica: revista del Instituto Nacional de Salud, Vol 43, Iss Sp. 1, Pp 206-216 (2023) covid-19 sars-cov-2 cryptococcus meningitis cryptococcal coinfection hiv infections Medicine R Arctic medicine. Tropical medicine RC955-962 article 2023 ftdoajarticles https://doi.org/10.7705/biomedica.6872 2023-09-24T00:42:19Z Introduction. Fungal infections in patients with COVID-19 was one of the most debated topics during the pandemic. Objectives. To analyze the clinical characteristics and evolution of people living with HIV/AIDS and coinfection with cryptococcus and COVID-19 (group A) or without it (group B). Materials and methods. This is an analytical and retrospective study. We reviewed medical records of patients with meningeal cryptococcosis between April 2020 and May 2021. Results. We studied 65 people living with HIV/AIDS and with cryptococcosis infection diagnosed from April 2020 to May 2021. Fifteen patients with HIV/AIDS suffered from cryptococcosis and COVID-19, and out of these, 14 presented meningitis (group A), while 28 suffered from meningeal cryptococcosis, but did not have COVID-19 (group B). Conclusions. No statistically significant differences were observed between the two groups (A and B) considering: intracranial hypertension, presence of Cryptococcus antigens in cerebrospinal fluid, sensorium deterioration or mortality. The detection of Cryptococcus antigens in serum by lateral flow assay was highly effective to rapidly diagnose cryptococcosis in patients with HIV/AIDS who also developed COVID-19. Patients of both groups consulted for cryptoccocosis sometime after, in comparison with the pre-pandemic cases related to this infection. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Biomédica 43 Sp. 1 206 216 |
institution |
Open Polar |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English Spanish |
topic |
covid-19 sars-cov-2 cryptococcus meningitis cryptococcal coinfection hiv infections Medicine R Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
covid-19 sars-cov-2 cryptococcus meningitis cryptococcal coinfection hiv infections Medicine R Arctic medicine. Tropical medicine RC955-962 Fernando Antonio Messina Andrés Benchetrit Andrea Bocassi María de las Mercedes Romero Sofía Bauer Emmanuel Marín Facundo Bertera Guillermo Onis Matías Enzenhofer Milagro Sánchez Lilia Mammana Dana Mijalovsky Gabriela Santiso Meningeal cryptococcosis and SARS-CoV-2 infection in people living with HIV/AIDS |
topic_facet |
covid-19 sars-cov-2 cryptococcus meningitis cryptococcal coinfection hiv infections Medicine R Arctic medicine. Tropical medicine RC955-962 |
description |
Introduction. Fungal infections in patients with COVID-19 was one of the most debated topics during the pandemic. Objectives. To analyze the clinical characteristics and evolution of people living with HIV/AIDS and coinfection with cryptococcus and COVID-19 (group A) or without it (group B). Materials and methods. This is an analytical and retrospective study. We reviewed medical records of patients with meningeal cryptococcosis between April 2020 and May 2021. Results. We studied 65 people living with HIV/AIDS and with cryptococcosis infection diagnosed from April 2020 to May 2021. Fifteen patients with HIV/AIDS suffered from cryptococcosis and COVID-19, and out of these, 14 presented meningitis (group A), while 28 suffered from meningeal cryptococcosis, but did not have COVID-19 (group B). Conclusions. No statistically significant differences were observed between the two groups (A and B) considering: intracranial hypertension, presence of Cryptococcus antigens in cerebrospinal fluid, sensorium deterioration or mortality. The detection of Cryptococcus antigens in serum by lateral flow assay was highly effective to rapidly diagnose cryptococcosis in patients with HIV/AIDS who also developed COVID-19. Patients of both groups consulted for cryptoccocosis sometime after, in comparison with the pre-pandemic cases related to this infection. |
format |
Article in Journal/Newspaper |
author |
Fernando Antonio Messina Andrés Benchetrit Andrea Bocassi María de las Mercedes Romero Sofía Bauer Emmanuel Marín Facundo Bertera Guillermo Onis Matías Enzenhofer Milagro Sánchez Lilia Mammana Dana Mijalovsky Gabriela Santiso |
author_facet |
Fernando Antonio Messina Andrés Benchetrit Andrea Bocassi María de las Mercedes Romero Sofía Bauer Emmanuel Marín Facundo Bertera Guillermo Onis Matías Enzenhofer Milagro Sánchez Lilia Mammana Dana Mijalovsky Gabriela Santiso |
author_sort |
Fernando Antonio Messina |
title |
Meningeal cryptococcosis and SARS-CoV-2 infection in people living with HIV/AIDS |
title_short |
Meningeal cryptococcosis and SARS-CoV-2 infection in people living with HIV/AIDS |
title_full |
Meningeal cryptococcosis and SARS-CoV-2 infection in people living with HIV/AIDS |
title_fullStr |
Meningeal cryptococcosis and SARS-CoV-2 infection in people living with HIV/AIDS |
title_full_unstemmed |
Meningeal cryptococcosis and SARS-CoV-2 infection in people living with HIV/AIDS |
title_sort |
meningeal cryptococcosis and sars-cov-2 infection in people living with hiv/aids |
publisher |
Instituto Nacional de Salud |
publishDate |
2023 |
url |
https://doi.org/10.7705/biomedica.6872 https://doaj.org/article/bf805caaa55f448a91adf50b5ca07aeb |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Biomédica: revista del Instituto Nacional de Salud, Vol 43, Iss Sp. 1, Pp 206-216 (2023) |
op_relation |
https://revistabiomedica.org/index.php/biomedica/article/view/6872 https://doaj.org/toc/0120-4157 0120-4157 doi:10.7705/biomedica.6872 https://doaj.org/article/bf805caaa55f448a91adf50b5ca07aeb |
op_doi |
https://doi.org/10.7705/biomedica.6872 |
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Biomédica |
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43 |
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Sp. 1 |
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206 |
op_container_end_page |
216 |
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