Colorectal cancer in an Eastern Caribbean nation: are we missing an opportunity for secondary prevention?
Objective. To establish whether there was any difference in disease stage in patients with screening-detected colorectal cancer (CRC) in a Caribbean country. Methods. The mode of presentation (elective vs. emergent), method of diagnosis (screening vs. symptomatic), and disease stage were retrospecti...
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2022
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ftdoajarticles:oai:doaj.org/article:bef2e06836d24b7e912cb54835e750b6 2023-05-15T15:11:11+02:00 Colorectal cancer in an Eastern Caribbean nation: are we missing an opportunity for secondary prevention? Shamir O. Cawich Emil Phillips Sierra Moore Solange Ramkissoon Greg Padmore Sahle Griffith 2022-04-01T00:00:00Z https://doi.org/10.26633/RPSP.2022.18 https://doaj.org/article/bef2e06836d24b7e912cb54835e750b6 EN ES PT eng spa por Pan American Health Organization https://iris.paho.org/handle/10665.2/55891 https://doaj.org/toc/1020-4989 https://doaj.org/toc/1680-5348 1020-4989 1680-5348 doi:10.26633/RPSP.2022.18 https://doaj.org/article/bef2e06836d24b7e912cb54835e750b6 Revista Panamericana de Salud Pública, Vol 46, Iss 18, Pp 1-5 (2022) colorectal neoplasms barbados caribbean region Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2022 ftdoajarticles https://doi.org/10.26633/RPSP.2022.18 2022-12-31T10:20:24Z Objective. To establish whether there was any difference in disease stage in patients with screening-detected colorectal cancer (CRC) in a Caribbean country. Methods. The mode of presentation (elective vs. emergent), method of diagnosis (screening vs. symptomatic), and disease stage were retrospectively compared in all consecutive patients who had resections for CRC over a five-year period. Early CRC was defined as disease that could be completely resected with no involvement of adjacent organs, lymph nodes, or distant sites. Locally advanced CRC was disease that involved contiguous organs without distant metastases that was still amenable to curative resection. Results. There were 97 patients at a mean age of 64.9 ± 12.2 years treated for CRC, and only 21 (21.6%) had their diagnoses made through screening. Significantly more screening-detected lesions were early-stage CRCs (21.7% vs. 9.3%; p < 0.001). At the time of diagnosis, patients who did not have screening-detected lesions had a greater proportion of locally advanced (42.3% vs. 0) and metastatic (26.8% vs. 0) CRC. Those who did not have screening-detected lesions had a greater incidence of emergency presentations at diagnosis (26.8% vs. 0). Conclusions. The incidence of screening-detected CRC in this Caribbean nation was low. Consequently, most patients presented with locally advanced or metastatic CRC, for which there is less opportunity to achieve a cure. Significantly more screening-detected lesions were early-stage CRCs. It is time for policymakers to develop a national CRC screening program. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista Panamericana de Salud Pública 46 1 |
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Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English Spanish Portuguese |
topic |
colorectal neoplasms barbados caribbean region Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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colorectal neoplasms barbados caribbean region Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Shamir O. Cawich Emil Phillips Sierra Moore Solange Ramkissoon Greg Padmore Sahle Griffith Colorectal cancer in an Eastern Caribbean nation: are we missing an opportunity for secondary prevention? |
topic_facet |
colorectal neoplasms barbados caribbean region Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Objective. To establish whether there was any difference in disease stage in patients with screening-detected colorectal cancer (CRC) in a Caribbean country. Methods. The mode of presentation (elective vs. emergent), method of diagnosis (screening vs. symptomatic), and disease stage were retrospectively compared in all consecutive patients who had resections for CRC over a five-year period. Early CRC was defined as disease that could be completely resected with no involvement of adjacent organs, lymph nodes, or distant sites. Locally advanced CRC was disease that involved contiguous organs without distant metastases that was still amenable to curative resection. Results. There were 97 patients at a mean age of 64.9 ± 12.2 years treated for CRC, and only 21 (21.6%) had their diagnoses made through screening. Significantly more screening-detected lesions were early-stage CRCs (21.7% vs. 9.3%; p < 0.001). At the time of diagnosis, patients who did not have screening-detected lesions had a greater proportion of locally advanced (42.3% vs. 0) and metastatic (26.8% vs. 0) CRC. Those who did not have screening-detected lesions had a greater incidence of emergency presentations at diagnosis (26.8% vs. 0). Conclusions. The incidence of screening-detected CRC in this Caribbean nation was low. Consequently, most patients presented with locally advanced or metastatic CRC, for which there is less opportunity to achieve a cure. Significantly more screening-detected lesions were early-stage CRCs. It is time for policymakers to develop a national CRC screening program. |
format |
Article in Journal/Newspaper |
author |
Shamir O. Cawich Emil Phillips Sierra Moore Solange Ramkissoon Greg Padmore Sahle Griffith |
author_facet |
Shamir O. Cawich Emil Phillips Sierra Moore Solange Ramkissoon Greg Padmore Sahle Griffith |
author_sort |
Shamir O. Cawich |
title |
Colorectal cancer in an Eastern Caribbean nation: are we missing an opportunity for secondary prevention? |
title_short |
Colorectal cancer in an Eastern Caribbean nation: are we missing an opportunity for secondary prevention? |
title_full |
Colorectal cancer in an Eastern Caribbean nation: are we missing an opportunity for secondary prevention? |
title_fullStr |
Colorectal cancer in an Eastern Caribbean nation: are we missing an opportunity for secondary prevention? |
title_full_unstemmed |
Colorectal cancer in an Eastern Caribbean nation: are we missing an opportunity for secondary prevention? |
title_sort |
colorectal cancer in an eastern caribbean nation: are we missing an opportunity for secondary prevention? |
publisher |
Pan American Health Organization |
publishDate |
2022 |
url |
https://doi.org/10.26633/RPSP.2022.18 https://doaj.org/article/bef2e06836d24b7e912cb54835e750b6 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista Panamericana de Salud Pública, Vol 46, Iss 18, Pp 1-5 (2022) |
op_relation |
https://iris.paho.org/handle/10665.2/55891 https://doaj.org/toc/1020-4989 https://doaj.org/toc/1680-5348 1020-4989 1680-5348 doi:10.26633/RPSP.2022.18 https://doaj.org/article/bef2e06836d24b7e912cb54835e750b6 |
op_doi |
https://doi.org/10.26633/RPSP.2022.18 |
container_title |
Revista Panamericana de Salud Pública |
container_volume |
46 |
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1 |
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