Entomological outcomes of cluster-randomised, community-driven dengue vector-suppression interventions in Kampong Cham province, Cambodia.
Cambodia has one of the highest dengue infection rates in Southeast Asia. Here we report quantitative entomological results of a large-scale cluster-randomised trial assessing the impact on vector populations of a package of vector control interventions including larvivorous guppy fish in household...
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ftdoajarticles:oai:doaj.org/article:bea6166011654479abba1b5f9bf6f4e7 2023-05-15T15:11:19+02:00 Entomological outcomes of cluster-randomised, community-driven dengue vector-suppression interventions in Kampong Cham province, Cambodia. Jacob Bigio Leo Braack Thy Chea Srun Set Sokha Suon Pierre Echaubard John Hustedt Mark Debackere Bernadette Ramirez Didot Budi Prasetyo Sam Bunleng Alexandra Wharton-Smith Jeffrey Hii 2022-01-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0010028 https://doaj.org/article/bea6166011654479abba1b5f9bf6f4e7 EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0010028 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0010028 https://doaj.org/article/bea6166011654479abba1b5f9bf6f4e7 PLoS Neglected Tropical Diseases, Vol 16, Iss 1, p e0010028 (2022) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2022 ftdoajarticles https://doi.org/10.1371/journal.pntd.0010028 2022-12-31T13:45:45Z Cambodia has one of the highest dengue infection rates in Southeast Asia. Here we report quantitative entomological results of a large-scale cluster-randomised trial assessing the impact on vector populations of a package of vector control interventions including larvivorous guppy fish in household water containers, mosquito trapping with gravid-ovitraps, solid waste management, breeding-container coverage through community education and engagement for behavioural change, particularly through the participation of school children. These activities resulted in major reductions in Container Index, House Index, Breteau Index, Pupal Index and Adult Index (all p-values 0.002 or lower) in the Intervention Arm compared with the Control Arm in a series of household surveys conducted over a follow-up period of more than one year, although the project was not able to measure the longer-term sustainability of the interventions. Despite comparative reductions in Adult Index between the study arms, the Adult Index was higher in the Intervention Arm in the final household survey than in the first household survey. This package of biophysical and community engagement interventions was highly effective in reducing entomological indices for dengue compared with the control group, but caution is required in extrapolating the reduction in household Adult Index to a reduction in the overall population of adult Aedes mosquitoes, and in interpreting the relationship between a reduction in entomological indices and a reduction in the number of dengue cases. The package of interventions should be trialled in other locations. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 16 1 e0010028 |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Jacob Bigio Leo Braack Thy Chea Srun Set Sokha Suon Pierre Echaubard John Hustedt Mark Debackere Bernadette Ramirez Didot Budi Prasetyo Sam Bunleng Alexandra Wharton-Smith Jeffrey Hii Entomological outcomes of cluster-randomised, community-driven dengue vector-suppression interventions in Kampong Cham province, Cambodia. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Cambodia has one of the highest dengue infection rates in Southeast Asia. Here we report quantitative entomological results of a large-scale cluster-randomised trial assessing the impact on vector populations of a package of vector control interventions including larvivorous guppy fish in household water containers, mosquito trapping with gravid-ovitraps, solid waste management, breeding-container coverage through community education and engagement for behavioural change, particularly through the participation of school children. These activities resulted in major reductions in Container Index, House Index, Breteau Index, Pupal Index and Adult Index (all p-values 0.002 or lower) in the Intervention Arm compared with the Control Arm in a series of household surveys conducted over a follow-up period of more than one year, although the project was not able to measure the longer-term sustainability of the interventions. Despite comparative reductions in Adult Index between the study arms, the Adult Index was higher in the Intervention Arm in the final household survey than in the first household survey. This package of biophysical and community engagement interventions was highly effective in reducing entomological indices for dengue compared with the control group, but caution is required in extrapolating the reduction in household Adult Index to a reduction in the overall population of adult Aedes mosquitoes, and in interpreting the relationship between a reduction in entomological indices and a reduction in the number of dengue cases. The package of interventions should be trialled in other locations. |
format |
Article in Journal/Newspaper |
author |
Jacob Bigio Leo Braack Thy Chea Srun Set Sokha Suon Pierre Echaubard John Hustedt Mark Debackere Bernadette Ramirez Didot Budi Prasetyo Sam Bunleng Alexandra Wharton-Smith Jeffrey Hii |
author_facet |
Jacob Bigio Leo Braack Thy Chea Srun Set Sokha Suon Pierre Echaubard John Hustedt Mark Debackere Bernadette Ramirez Didot Budi Prasetyo Sam Bunleng Alexandra Wharton-Smith Jeffrey Hii |
author_sort |
Jacob Bigio |
title |
Entomological outcomes of cluster-randomised, community-driven dengue vector-suppression interventions in Kampong Cham province, Cambodia. |
title_short |
Entomological outcomes of cluster-randomised, community-driven dengue vector-suppression interventions in Kampong Cham province, Cambodia. |
title_full |
Entomological outcomes of cluster-randomised, community-driven dengue vector-suppression interventions in Kampong Cham province, Cambodia. |
title_fullStr |
Entomological outcomes of cluster-randomised, community-driven dengue vector-suppression interventions in Kampong Cham province, Cambodia. |
title_full_unstemmed |
Entomological outcomes of cluster-randomised, community-driven dengue vector-suppression interventions in Kampong Cham province, Cambodia. |
title_sort |
entomological outcomes of cluster-randomised, community-driven dengue vector-suppression interventions in kampong cham province, cambodia. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2022 |
url |
https://doi.org/10.1371/journal.pntd.0010028 https://doaj.org/article/bea6166011654479abba1b5f9bf6f4e7 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 16, Iss 1, p e0010028 (2022) |
op_relation |
https://doi.org/10.1371/journal.pntd.0010028 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0010028 https://doaj.org/article/bea6166011654479abba1b5f9bf6f4e7 |
op_doi |
https://doi.org/10.1371/journal.pntd.0010028 |
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PLOS Neglected Tropical Diseases |
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16 |
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1 |
container_start_page |
e0010028 |
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