The economic burden of dengue fever in the Kingdom of Saudi Arabia.
Rapid urbanization, global trade, and the exceptionally great numbers of worldwide visitors during Hajj and Umrah have all placed the Kingdom of Saudi Arabia at a significant risk of introducing several vector-borne tropical diseases, such as dengue fever virus (DENV) infection. In this study we est...
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ftdoajarticles:oai:doaj.org/article:be956e2191db490aafde7d189e6e3168 2023-05-15T15:12:08+02:00 The economic burden of dengue fever in the Kingdom of Saudi Arabia. Naeema A Akbar Abdullah M Assiri Omima I Shabouni Osama M Alwafi Rajaa Al-Raddadi Mohamad H Alzahrani Esam I Azhar Ashraf Amir Abdullah M Aljiffri Abdulhakeem O Althaqafi 2020-11-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0008847 https://doaj.org/article/be956e2191db490aafde7d189e6e3168 EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0008847 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0008847 https://doaj.org/article/be956e2191db490aafde7d189e6e3168 PLoS Neglected Tropical Diseases, Vol 14, Iss 11, p e0008847 (2020) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2020 ftdoajarticles https://doi.org/10.1371/journal.pntd.0008847 2022-12-31T11:44:55Z Rapid urbanization, global trade, and the exceptionally great numbers of worldwide visitors during Hajj and Umrah have all placed the Kingdom of Saudi Arabia at a significant risk of introducing several vector-borne tropical diseases, such as dengue fever virus (DENV) infection. In this study we estimated DENV infection cost of illness (COI) in Saudi Arabia in the period 2013-2017, by processing national data including all declared cases recorded in referral centers in the western region, being the endemic region of the country. Using a statistically validated predictive model that was built on a representative sample of 717 laboratory-confirmed cases of DENV infection, direct costs, due to care-related expenditures, were estimated by applying the predictive equation to national data. However, indirect costs, which are due to productivity loss, were estimated using the human capital model based on gross domestic product adjusted for invalidity duration. Further, under-reporting was adjusted by using an expansion factor EF = 3. We observed highest estimated costs in 2016 with over US$168.5 Million total costs, including direct (US$29.0 Million) and indirect (US$139.5 Million) costs, for a total 4415 confirmed cases. The total DENV COI for the five years was estimated as US$551.0 Million for a total 15,369 patients (59.7%) out of 25,745 declared cases, resulting in an average cost of US$11 947.6 by patient. Depending on the year, productivity years loss costs accounted for 63.3% to 83.8% of the estimated total costs. Dengue has a substantial local economic burden that costs US$110.2 Million per year, stressing the urgent need for an effective national prevention strategy to perform considerable cost-savings besides reducing morbidity. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLOS Neglected Tropical Diseases 14 11 e0008847 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Naeema A Akbar Abdullah M Assiri Omima I Shabouni Osama M Alwafi Rajaa Al-Raddadi Mohamad H Alzahrani Esam I Azhar Ashraf Amir Abdullah M Aljiffri Abdulhakeem O Althaqafi The economic burden of dengue fever in the Kingdom of Saudi Arabia. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Rapid urbanization, global trade, and the exceptionally great numbers of worldwide visitors during Hajj and Umrah have all placed the Kingdom of Saudi Arabia at a significant risk of introducing several vector-borne tropical diseases, such as dengue fever virus (DENV) infection. In this study we estimated DENV infection cost of illness (COI) in Saudi Arabia in the period 2013-2017, by processing national data including all declared cases recorded in referral centers in the western region, being the endemic region of the country. Using a statistically validated predictive model that was built on a representative sample of 717 laboratory-confirmed cases of DENV infection, direct costs, due to care-related expenditures, were estimated by applying the predictive equation to national data. However, indirect costs, which are due to productivity loss, were estimated using the human capital model based on gross domestic product adjusted for invalidity duration. Further, under-reporting was adjusted by using an expansion factor EF = 3. We observed highest estimated costs in 2016 with over US$168.5 Million total costs, including direct (US$29.0 Million) and indirect (US$139.5 Million) costs, for a total 4415 confirmed cases. The total DENV COI for the five years was estimated as US$551.0 Million for a total 15,369 patients (59.7%) out of 25,745 declared cases, resulting in an average cost of US$11 947.6 by patient. Depending on the year, productivity years loss costs accounted for 63.3% to 83.8% of the estimated total costs. Dengue has a substantial local economic burden that costs US$110.2 Million per year, stressing the urgent need for an effective national prevention strategy to perform considerable cost-savings besides reducing morbidity. |
format |
Article in Journal/Newspaper |
author |
Naeema A Akbar Abdullah M Assiri Omima I Shabouni Osama M Alwafi Rajaa Al-Raddadi Mohamad H Alzahrani Esam I Azhar Ashraf Amir Abdullah M Aljiffri Abdulhakeem O Althaqafi |
author_facet |
Naeema A Akbar Abdullah M Assiri Omima I Shabouni Osama M Alwafi Rajaa Al-Raddadi Mohamad H Alzahrani Esam I Azhar Ashraf Amir Abdullah M Aljiffri Abdulhakeem O Althaqafi |
author_sort |
Naeema A Akbar |
title |
The economic burden of dengue fever in the Kingdom of Saudi Arabia. |
title_short |
The economic burden of dengue fever in the Kingdom of Saudi Arabia. |
title_full |
The economic burden of dengue fever in the Kingdom of Saudi Arabia. |
title_fullStr |
The economic burden of dengue fever in the Kingdom of Saudi Arabia. |
title_full_unstemmed |
The economic burden of dengue fever in the Kingdom of Saudi Arabia. |
title_sort |
economic burden of dengue fever in the kingdom of saudi arabia. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2020 |
url |
https://doi.org/10.1371/journal.pntd.0008847 https://doaj.org/article/be956e2191db490aafde7d189e6e3168 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 14, Iss 11, p e0008847 (2020) |
op_relation |
https://doi.org/10.1371/journal.pntd.0008847 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0008847 https://doaj.org/article/be956e2191db490aafde7d189e6e3168 |
op_doi |
https://doi.org/10.1371/journal.pntd.0008847 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
14 |
container_issue |
11 |
container_start_page |
e0008847 |
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1766342863985049600 |