Role of sph2 Gene Regulation in Hemolytic and Sphingomyelinase Activities Produced by Leptospira interrogans.

• Published in: PLOS Neglected Tropical Diseases
• Main Authors: Suneel A Narayanavari, Kristel Lourdault, Manjula Sritharan, David A Haake, James Matsunaga
• Format: Article in Journal/Newspaper
• Language: English
• Published: Public Library of Science (PLoS) 2015
• Subjects: Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic; Pomona
• Online Access: https://doi.org/10.1371/journal.pntd.0003952; https://doaj.org/article/be400baf5c80466aa4777155efea1cd7

Pathogenic members of the genus Leptospira are the causative agents of leptospirosis, a neglected disease of public and veterinary health concern. Leptospirosis is a systemic disease that in its severest forms leads to renal insufficiency, hepatic dysfunction, and pulmonary failure. Many strains of...