Reinvestigating the status of malaria parasite (Plasmodium sp.) in Indian non-human primates.
Many human parasites and pathogens have closely related counterparts among non-human primates. For example, non-human primates harbour several species of malaria causing parasites of the genus Plasmodium. Studies suggest that for a better understanding of the origin and evolution of human malaria pa...
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ftdoajarticles:oai:doaj.org/article:bdf449109dc8499ebea05e832d0ba96b 2023-05-15T15:13:24+02:00 Reinvestigating the status of malaria parasite (Plasmodium sp.) in Indian non-human primates. Jyotsana Dixit Arun Zachariah Sajesh P K Bathrachalam Chandramohan Vinoth Shanmuganatham K Praveen Karanth 2018-12-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0006801 https://doaj.org/article/bdf449109dc8499ebea05e832d0ba96b EN eng Public Library of Science (PLoS) https://doi.org/10.1371/journal.pntd.0006801 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0006801 https://doaj.org/article/bdf449109dc8499ebea05e832d0ba96b PLoS Neglected Tropical Diseases, Vol 12, Iss 12, p e0006801 (2018) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2018 ftdoajarticles https://doi.org/10.1371/journal.pntd.0006801 2022-12-31T07:16:57Z Many human parasites and pathogens have closely related counterparts among non-human primates. For example, non-human primates harbour several species of malaria causing parasites of the genus Plasmodium. Studies suggest that for a better understanding of the origin and evolution of human malaria parasites it is important to know the diversity and evolutionary relationships of these parasites in non-human primates. Much work has been undertaken on malaria parasites in wild great Apes of Africa as well as wild monkeys of Southeast Asia however studies are lacking from South Asia, particularly India. India is one of the major malaria prone regions in the world and exhibits high primate diversity which in turn provides ideal setting for both zoonoses and anthropozoonoses. In this study we report the molecular data for malaria parasites from wild populations of Indian non-human primates. We surveyed 349 fecal samples from five different Indian non-human primates, while 94 blood and tissue samples from one of the Indian non-human primate species (Macaca radiata) and one blood sample from M. mulatta. Our results confirm the presence of P. fragile, P. inui and P. cynomolgi in Macaca radiata. Additionally, we report for the first time the presence of human malarial parasite, P. falciparum, in M. mulatta and M. radiata. Additionally, our results indicate that M. radiata does not exhibit population structure probably due to human mediated translocation of problem monkeys. Human mediated transport of macaques adds an additional level of complexity to tacking malaria in human. This issue has implications for both the spread of primate as well as human specific malarias. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Indian PLOS Neglected Tropical Diseases 12 12 e0006801 |
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Directory of Open Access Journals: DOAJ Articles |
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English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Jyotsana Dixit Arun Zachariah Sajesh P K Bathrachalam Chandramohan Vinoth Shanmuganatham K Praveen Karanth Reinvestigating the status of malaria parasite (Plasmodium sp.) in Indian non-human primates. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
Many human parasites and pathogens have closely related counterparts among non-human primates. For example, non-human primates harbour several species of malaria causing parasites of the genus Plasmodium. Studies suggest that for a better understanding of the origin and evolution of human malaria parasites it is important to know the diversity and evolutionary relationships of these parasites in non-human primates. Much work has been undertaken on malaria parasites in wild great Apes of Africa as well as wild monkeys of Southeast Asia however studies are lacking from South Asia, particularly India. India is one of the major malaria prone regions in the world and exhibits high primate diversity which in turn provides ideal setting for both zoonoses and anthropozoonoses. In this study we report the molecular data for malaria parasites from wild populations of Indian non-human primates. We surveyed 349 fecal samples from five different Indian non-human primates, while 94 blood and tissue samples from one of the Indian non-human primate species (Macaca radiata) and one blood sample from M. mulatta. Our results confirm the presence of P. fragile, P. inui and P. cynomolgi in Macaca radiata. Additionally, we report for the first time the presence of human malarial parasite, P. falciparum, in M. mulatta and M. radiata. Additionally, our results indicate that M. radiata does not exhibit population structure probably due to human mediated translocation of problem monkeys. Human mediated transport of macaques adds an additional level of complexity to tacking malaria in human. This issue has implications for both the spread of primate as well as human specific malarias. |
format |
Article in Journal/Newspaper |
author |
Jyotsana Dixit Arun Zachariah Sajesh P K Bathrachalam Chandramohan Vinoth Shanmuganatham K Praveen Karanth |
author_facet |
Jyotsana Dixit Arun Zachariah Sajesh P K Bathrachalam Chandramohan Vinoth Shanmuganatham K Praveen Karanth |
author_sort |
Jyotsana Dixit |
title |
Reinvestigating the status of malaria parasite (Plasmodium sp.) in Indian non-human primates. |
title_short |
Reinvestigating the status of malaria parasite (Plasmodium sp.) in Indian non-human primates. |
title_full |
Reinvestigating the status of malaria parasite (Plasmodium sp.) in Indian non-human primates. |
title_fullStr |
Reinvestigating the status of malaria parasite (Plasmodium sp.) in Indian non-human primates. |
title_full_unstemmed |
Reinvestigating the status of malaria parasite (Plasmodium sp.) in Indian non-human primates. |
title_sort |
reinvestigating the status of malaria parasite (plasmodium sp.) in indian non-human primates. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2018 |
url |
https://doi.org/10.1371/journal.pntd.0006801 https://doaj.org/article/bdf449109dc8499ebea05e832d0ba96b |
geographic |
Arctic Indian |
geographic_facet |
Arctic Indian |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 12, Iss 12, p e0006801 (2018) |
op_relation |
https://doi.org/10.1371/journal.pntd.0006801 https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0006801 https://doaj.org/article/bdf449109dc8499ebea05e832d0ba96b |
op_doi |
https://doi.org/10.1371/journal.pntd.0006801 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
12 |
container_issue |
12 |
container_start_page |
e0006801 |
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1766343955955318784 |