Clinical manifestations associated with neurocysticercosis: a systematic review.
BACKGROUND: The clinical manifestations of neurocysticercosis (NCC) are poorly understood. This systematic review aims to estimate the frequencies of different manifestations, complications and disabilities associated with NCC. METHODS: A systematic search of the literature published from January 1,...
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ftdoajarticles:oai:doaj.org/article:bddbadc0578345bc8330ee48fe300ec1 2023-05-15T15:07:38+02:00 Clinical manifestations associated with neurocysticercosis: a systematic review. Hélène Carabin Patrick Cyaga Ndimubanzi Christine M Budke Hai Nguyen Yingjun Qian Linda Demetry Cowan Julie Ann Stoner Elizabeth Rainwater Mary Dickey 2011-05-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0001152 https://doaj.org/article/bddbadc0578345bc8330ee48fe300ec1 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC3101170?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 doi:10.1371/journal.pntd.0001152 1935-2727 1935-2735 https://doaj.org/article/bddbadc0578345bc8330ee48fe300ec1 PLoS Neglected Tropical Diseases, Vol 5, Iss 5, p e1152 (2011) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2011 ftdoajarticles https://doi.org/10.1371/journal.pntd.0001152 2022-12-31T01:28:22Z BACKGROUND: The clinical manifestations of neurocysticercosis (NCC) are poorly understood. This systematic review aims to estimate the frequencies of different manifestations, complications and disabilities associated with NCC. METHODS: A systematic search of the literature published from January 1, 1990, to June 1, 2008, in 24 different electronic databases and 8 languages was conducted. Meta-analyses were conducted when appropriate. RESULTS: A total of 1569 documents were identified, and 21 included in the analysis. Among patients seen in neurology clinics, seizures/epilepsy were the most common manifestations (78.8%, 95%CI: 65.1%-89.7%) followed by headaches (37.9%, 95%CI: 23.3%-53.7%), focal deficits (16.0%, 95%CI: 9.7%-23.6%) and signs of increased intracranial pressure (11.7%, 95%CI: 6.0%-18.9%). All other manifestations occurred in less than 10% of symptomatic NCC patients. Only four studies reported on the mortality rate of NCC. CONCLUSIONS: NCC is a pleomorphic disease linked to a range of manifestations. Although definitions of manifestations were very rarely provided, and varied from study to study, the proportion of NCC cases with seizures/epilepsy and the proportion of headaches were consistent across studies. These estimates are only applicable to patients who are ill enough to seek care in neurology clinics and likely over estimate the frequency of manifestations among all NCC cases. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic PLoS Neglected Tropical Diseases 5 5 e1152 |
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Directory of Open Access Journals: DOAJ Articles |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Hélène Carabin Patrick Cyaga Ndimubanzi Christine M Budke Hai Nguyen Yingjun Qian Linda Demetry Cowan Julie Ann Stoner Elizabeth Rainwater Mary Dickey Clinical manifestations associated with neurocysticercosis: a systematic review. |
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Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
BACKGROUND: The clinical manifestations of neurocysticercosis (NCC) are poorly understood. This systematic review aims to estimate the frequencies of different manifestations, complications and disabilities associated with NCC. METHODS: A systematic search of the literature published from January 1, 1990, to June 1, 2008, in 24 different electronic databases and 8 languages was conducted. Meta-analyses were conducted when appropriate. RESULTS: A total of 1569 documents were identified, and 21 included in the analysis. Among patients seen in neurology clinics, seizures/epilepsy were the most common manifestations (78.8%, 95%CI: 65.1%-89.7%) followed by headaches (37.9%, 95%CI: 23.3%-53.7%), focal deficits (16.0%, 95%CI: 9.7%-23.6%) and signs of increased intracranial pressure (11.7%, 95%CI: 6.0%-18.9%). All other manifestations occurred in less than 10% of symptomatic NCC patients. Only four studies reported on the mortality rate of NCC. CONCLUSIONS: NCC is a pleomorphic disease linked to a range of manifestations. Although definitions of manifestations were very rarely provided, and varied from study to study, the proportion of NCC cases with seizures/epilepsy and the proportion of headaches were consistent across studies. These estimates are only applicable to patients who are ill enough to seek care in neurology clinics and likely over estimate the frequency of manifestations among all NCC cases. |
format |
Article in Journal/Newspaper |
author |
Hélène Carabin Patrick Cyaga Ndimubanzi Christine M Budke Hai Nguyen Yingjun Qian Linda Demetry Cowan Julie Ann Stoner Elizabeth Rainwater Mary Dickey |
author_facet |
Hélène Carabin Patrick Cyaga Ndimubanzi Christine M Budke Hai Nguyen Yingjun Qian Linda Demetry Cowan Julie Ann Stoner Elizabeth Rainwater Mary Dickey |
author_sort |
Hélène Carabin |
title |
Clinical manifestations associated with neurocysticercosis: a systematic review. |
title_short |
Clinical manifestations associated with neurocysticercosis: a systematic review. |
title_full |
Clinical manifestations associated with neurocysticercosis: a systematic review. |
title_fullStr |
Clinical manifestations associated with neurocysticercosis: a systematic review. |
title_full_unstemmed |
Clinical manifestations associated with neurocysticercosis: a systematic review. |
title_sort |
clinical manifestations associated with neurocysticercosis: a systematic review. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2011 |
url |
https://doi.org/10.1371/journal.pntd.0001152 https://doaj.org/article/bddbadc0578345bc8330ee48fe300ec1 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 5, Iss 5, p e1152 (2011) |
op_relation |
http://europepmc.org/articles/PMC3101170?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 doi:10.1371/journal.pntd.0001152 1935-2727 1935-2735 https://doaj.org/article/bddbadc0578345bc8330ee48fe300ec1 |
op_doi |
https://doi.org/10.1371/journal.pntd.0001152 |
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PLoS Neglected Tropical Diseases |
container_volume |
5 |
container_issue |
5 |
container_start_page |
e1152 |
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1766339098324238336 |