Osseous cystic echinococcosis: A case series study at a referral unit in Spain.
BACKGROUND:Cystic echinococcosis (CE) is present in all continents, except for the Antarctica. Characteristically, CE lesions are found in the liver and the lungs, but virtually any part of the body may be affected (the spleen, kidneys, heart, central nervous system, bones, among others). It is esti...
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ftdoajarticles:oai:doaj.org/article:bbbf16ebb4624ae2b50ca9de0ff13989 2023-05-15T14:00:32+02:00 Osseous cystic echinococcosis: A case series study at a referral unit in Spain. Begoña Monge-Maillo María Olmedo Samperio José Antonio Pérez-Molina Francesca Norman Carla Ruth Mejía Sandra Chamorro Tojeiro Rogelio López-Vélez 2019-02-01T00:00:00Z https://doi.org/10.1371/journal.pntd.0007006 https://doaj.org/article/bbbf16ebb4624ae2b50ca9de0ff13989 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC6396934?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0007006 https://doaj.org/article/bbbf16ebb4624ae2b50ca9de0ff13989 PLoS Neglected Tropical Diseases, Vol 13, Iss 2, p e0007006 (2019) Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2019 ftdoajarticles https://doi.org/10.1371/journal.pntd.0007006 2022-12-31T16:03:23Z BACKGROUND:Cystic echinococcosis (CE) is present in all continents, except for the Antarctica. Characteristically, CE lesions are found in the liver and the lungs, but virtually any part of the body may be affected (the spleen, kidneys, heart, central nervous system, bones, among others). It is estimated that the incidence of bone involvement in CE is 0.5% to 4%. METHODOLOGY:A retrospective study was performed of patients with osseous CE treated at the National Reference Unit of Tropical Diseases of the Ramon y Cajal Hospital, Madrid, Spain, between 1989 and December 2017. Epidemiological, clinical, diagnostic and therapeutic data of patients with long-term follow-up were collected. MAIN FINDINGS:During the study period, of the 104 patients with CE, 27 exhibited bone involvement (26%). The bones most frequently affected were the spine, followed by the ribs, pelvis, femur, tibia and the scapula. The most common symptom was pain followed by medullar syndrome and pathologic fracture. In total, 81.5% of patients underwent surgery for osseous CE at least once. As many as 96% received albendazol either in (mostly long-term) monotherapy or in combination with praziquantel. CONCLUSIONS:The diagnosis and management of osseous CE is challenging. In many cases osseous CE should be considered a chronic disease and should be managed on a case-by-case basis. Lifelong follow-up should be performed for potential recurrence and sequels. Article in Journal/Newspaper Antarc* Antarctica Arctic Directory of Open Access Journals: DOAJ Articles Arctic The Ribs ENVELOPE(-55.781,-55.781,52.750,52.750) PLOS Neglected Tropical Diseases 13 2 e0007006 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Begoña Monge-Maillo María Olmedo Samperio José Antonio Pérez-Molina Francesca Norman Carla Ruth Mejía Sandra Chamorro Tojeiro Rogelio López-Vélez Osseous cystic echinococcosis: A case series study at a referral unit in Spain. |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
BACKGROUND:Cystic echinococcosis (CE) is present in all continents, except for the Antarctica. Characteristically, CE lesions are found in the liver and the lungs, but virtually any part of the body may be affected (the spleen, kidneys, heart, central nervous system, bones, among others). It is estimated that the incidence of bone involvement in CE is 0.5% to 4%. METHODOLOGY:A retrospective study was performed of patients with osseous CE treated at the National Reference Unit of Tropical Diseases of the Ramon y Cajal Hospital, Madrid, Spain, between 1989 and December 2017. Epidemiological, clinical, diagnostic and therapeutic data of patients with long-term follow-up were collected. MAIN FINDINGS:During the study period, of the 104 patients with CE, 27 exhibited bone involvement (26%). The bones most frequently affected were the spine, followed by the ribs, pelvis, femur, tibia and the scapula. The most common symptom was pain followed by medullar syndrome and pathologic fracture. In total, 81.5% of patients underwent surgery for osseous CE at least once. As many as 96% received albendazol either in (mostly long-term) monotherapy or in combination with praziquantel. CONCLUSIONS:The diagnosis and management of osseous CE is challenging. In many cases osseous CE should be considered a chronic disease and should be managed on a case-by-case basis. Lifelong follow-up should be performed for potential recurrence and sequels. |
format |
Article in Journal/Newspaper |
author |
Begoña Monge-Maillo María Olmedo Samperio José Antonio Pérez-Molina Francesca Norman Carla Ruth Mejía Sandra Chamorro Tojeiro Rogelio López-Vélez |
author_facet |
Begoña Monge-Maillo María Olmedo Samperio José Antonio Pérez-Molina Francesca Norman Carla Ruth Mejía Sandra Chamorro Tojeiro Rogelio López-Vélez |
author_sort |
Begoña Monge-Maillo |
title |
Osseous cystic echinococcosis: A case series study at a referral unit in Spain. |
title_short |
Osseous cystic echinococcosis: A case series study at a referral unit in Spain. |
title_full |
Osseous cystic echinococcosis: A case series study at a referral unit in Spain. |
title_fullStr |
Osseous cystic echinococcosis: A case series study at a referral unit in Spain. |
title_full_unstemmed |
Osseous cystic echinococcosis: A case series study at a referral unit in Spain. |
title_sort |
osseous cystic echinococcosis: a case series study at a referral unit in spain. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2019 |
url |
https://doi.org/10.1371/journal.pntd.0007006 https://doaj.org/article/bbbf16ebb4624ae2b50ca9de0ff13989 |
long_lat |
ENVELOPE(-55.781,-55.781,52.750,52.750) |
geographic |
Arctic The Ribs |
geographic_facet |
Arctic The Ribs |
genre |
Antarc* Antarctica Arctic |
genre_facet |
Antarc* Antarctica Arctic |
op_source |
PLoS Neglected Tropical Diseases, Vol 13, Iss 2, p e0007006 (2019) |
op_relation |
http://europepmc.org/articles/PMC6396934?pdf=render https://doaj.org/toc/1935-2727 https://doaj.org/toc/1935-2735 1935-2727 1935-2735 doi:10.1371/journal.pntd.0007006 https://doaj.org/article/bbbf16ebb4624ae2b50ca9de0ff13989 |
op_doi |
https://doi.org/10.1371/journal.pntd.0007006 |
container_title |
PLOS Neglected Tropical Diseases |
container_volume |
13 |
container_issue |
2 |
container_start_page |
e0007006 |
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1766269705460383744 |