Thermal and oxidative stability of Atlantic salmon oil (Salmo salar L.) and complexation with β-cyclodextrin

• Published in: Beilstein Journal of Organic Chemistry
• Main Authors: Daniel I. Hădărugă, Mustafa Ünlüsayin, Alexandra T. Gruia, Cristina Birău (Mitroi), Gerlinde Rusu, Nicoleta G. Hădărugă
• Format: Article in Journal/Newspaper
• Language: English
• Published: Beilstein-Institut 2016
• Subjects: Atlantic salmon oil (ASO); β-cyclodextrin; differential scanning calorimetry; Karl Fischer titration; omega-3 fatty acid; thermogravimetry; Science; Q; Organic chemistry; QD241-441; Atlantic salmon; Salmo salar
• Online Access: https://doi.org/10.3762/bjoc.12.20; https://doaj.org/article/bbb6bbe1ba154c91a804109437061144

The thermal and oxidative stability of Atlantic salmon oil (Salmo salar L.) as well as its β-cyclodextrin (β-CD) complexation ability has been verified for the first time. The main omega-3 fatty acids, EPA and DHA, were significantly degraded, even at 50 °C. Their relative concentrations decrease from 6.1% for EPA and 4.1% for DHA to 1.7% and 1.5% after degradation at 150 °C, respectively. On the other hand, the relative concentrations of monounsaturated and saturated fatty acids remained constant or slightly increased by a few percent after degradation (e.g., from 10.7% to 12.9% for palmitic acid). Co-crystallization of ASO with β-CD at a host–guest ratio of 1:1 and 3:1 from an ethanol–water mixture and kneading methods has been used for the preparation of β-CD/ASO complexes. The analysis of the complexes by thermogravimetry, differential scanning calorimetry (DSC), and Karl Fischer titration (KFT) as well as the decrease of the “strongly-retained” water content confirm the formation of the inclusion compound. Furthermore, the DSC parameters correlate well with the KFT kinetic data for β-CD/ASO complexes.