Application of the indirect fluorescent antibody assay in the study of malaria infection in the Yangtze River Three Gorges Reservoir, China
Abstract Background China Yangtze Three Gorges Project (TGP) is one of the biggest construction projects in the world. The areas around the Three Gorge Dam has a history of tertian malaria and subtertian malaria epidemic, but there are no overall data about malaria epidemics before the completion of...
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ftdoajarticles:oai:doaj.org/article:bb0e4e0b48c44f9fa6fd3ff7144c5069 2023-05-15T15:10:09+02:00 Application of the indirect fluorescent antibody assay in the study of malaria infection in the Yangtze River Three Gorges Reservoir, China Xiang Zheng Zhen-Cheng Gu Lin-Hua Tang Duo-Quan Wang Man-Ni Yang 2009-08-01T00:00:00Z https://doi.org/10.1186/1475-2875-8-199 https://doaj.org/article/bb0e4e0b48c44f9fa6fd3ff7144c5069 EN eng BMC http://www.malariajournal.com/content/8/1/199 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-8-199 1475-2875 https://doaj.org/article/bb0e4e0b48c44f9fa6fd3ff7144c5069 Malaria Journal, Vol 8, Iss 1, p 199 (2009) Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 article 2009 ftdoajarticles https://doi.org/10.1186/1475-2875-8-199 2022-12-31T11:46:20Z Abstract Background China Yangtze Three Gorges Project (TGP) is one of the biggest construction projects in the world. The areas around the Three Gorge Dam has a history of tertian malaria and subtertian malaria epidemic, but there are no overall data about malaria epidemics before the completion of the project. The objective of this study was to get a reliable baseline on malaria infection in the Yangtze River Three Gorges reservoir area and to provide reference data for future studies about the impact of the project on malaria epidemics. Methods Two surveys of malaria infection were carried out in area, at six-month intervals in May and October 2008. About 3,600 dual specimens blood film samples for parasite diagnosis and filter paper blood spots for serology (using the immunofluorescence antibody test) were collected from the general population, including school populations, whenever possible. Results The overall percentage of positive response of the same population during post-transmission periods was about twice (1.40/0.72) of that in pre-transmission. Positive individuals under 15 years of age were detected in all the localities. Conclusion A certain extent of malaria infection existed in this area. Additional studies are needed to determine the length of malaria experience, and chemotherapeutic intervention as well as the distribution of main vectors for transmission in this area. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Malaria Journal 8 1 199 |
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Directory of Open Access Journals: DOAJ Articles |
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English |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
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Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 Xiang Zheng Zhen-Cheng Gu Lin-Hua Tang Duo-Quan Wang Man-Ni Yang Application of the indirect fluorescent antibody assay in the study of malaria infection in the Yangtze River Three Gorges Reservoir, China |
topic_facet |
Arctic medicine. Tropical medicine RC955-962 Infectious and parasitic diseases RC109-216 |
description |
Abstract Background China Yangtze Three Gorges Project (TGP) is one of the biggest construction projects in the world. The areas around the Three Gorge Dam has a history of tertian malaria and subtertian malaria epidemic, but there are no overall data about malaria epidemics before the completion of the project. The objective of this study was to get a reliable baseline on malaria infection in the Yangtze River Three Gorges reservoir area and to provide reference data for future studies about the impact of the project on malaria epidemics. Methods Two surveys of malaria infection were carried out in area, at six-month intervals in May and October 2008. About 3,600 dual specimens blood film samples for parasite diagnosis and filter paper blood spots for serology (using the immunofluorescence antibody test) were collected from the general population, including school populations, whenever possible. Results The overall percentage of positive response of the same population during post-transmission periods was about twice (1.40/0.72) of that in pre-transmission. Positive individuals under 15 years of age were detected in all the localities. Conclusion A certain extent of malaria infection existed in this area. Additional studies are needed to determine the length of malaria experience, and chemotherapeutic intervention as well as the distribution of main vectors for transmission in this area. |
format |
Article in Journal/Newspaper |
author |
Xiang Zheng Zhen-Cheng Gu Lin-Hua Tang Duo-Quan Wang Man-Ni Yang |
author_facet |
Xiang Zheng Zhen-Cheng Gu Lin-Hua Tang Duo-Quan Wang Man-Ni Yang |
author_sort |
Xiang Zheng |
title |
Application of the indirect fluorescent antibody assay in the study of malaria infection in the Yangtze River Three Gorges Reservoir, China |
title_short |
Application of the indirect fluorescent antibody assay in the study of malaria infection in the Yangtze River Three Gorges Reservoir, China |
title_full |
Application of the indirect fluorescent antibody assay in the study of malaria infection in the Yangtze River Three Gorges Reservoir, China |
title_fullStr |
Application of the indirect fluorescent antibody assay in the study of malaria infection in the Yangtze River Three Gorges Reservoir, China |
title_full_unstemmed |
Application of the indirect fluorescent antibody assay in the study of malaria infection in the Yangtze River Three Gorges Reservoir, China |
title_sort |
application of the indirect fluorescent antibody assay in the study of malaria infection in the yangtze river three gorges reservoir, china |
publisher |
BMC |
publishDate |
2009 |
url |
https://doi.org/10.1186/1475-2875-8-199 https://doaj.org/article/bb0e4e0b48c44f9fa6fd3ff7144c5069 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Malaria Journal, Vol 8, Iss 1, p 199 (2009) |
op_relation |
http://www.malariajournal.com/content/8/1/199 https://doaj.org/toc/1475-2875 doi:10.1186/1475-2875-8-199 1475-2875 https://doaj.org/article/bb0e4e0b48c44f9fa6fd3ff7144c5069 |
op_doi |
https://doi.org/10.1186/1475-2875-8-199 |
container_title |
Malaria Journal |
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8 |
container_issue |
1 |
container_start_page |
199 |
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1766341200715972608 |