Histopathological characterisation of retinal lesions associated to Diplostomum species (Platyhelminthes: Trematoda) infection in polymorphic Arctic charr Salvelinus alpinus
The eye represents an immune privileged organ where parasites can escape host reactions. This study provides the first systematic evidence of the pathology associated with Diplostomum sp. infection in the eye retina of fish (i.e. Arctic charr). Histological sections showed that the trematodes caused...
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ftdoajarticles:oai:doaj.org/article:bafb2cf8f8da4805b8ffe43a719460cc 2023-05-15T14:30:05+02:00 Histopathological characterisation of retinal lesions associated to Diplostomum species (Platyhelminthes: Trematoda) infection in polymorphic Arctic charr Salvelinus alpinus F. Padrós R. Knudsen I. Blasco-Costa 2018-04-01T00:00:00Z https://doi.org/10.1016/j.ijppaw.2018.01.007 https://doaj.org/article/bafb2cf8f8da4805b8ffe43a719460cc EN eng Elsevier http://www.sciencedirect.com/science/article/pii/S221322441730130X https://doaj.org/toc/2213-2244 2213-2244 doi:10.1016/j.ijppaw.2018.01.007 https://doaj.org/article/bafb2cf8f8da4805b8ffe43a719460cc International Journal for Parasitology: Parasites and Wildlife, Vol 7, Iss 1, Pp 68-74 (2018) Zoology QL1-991 article 2018 ftdoajarticles https://doi.org/10.1016/j.ijppaw.2018.01.007 2022-12-31T00:26:24Z The eye represents an immune privileged organ where parasites can escape host reactions. This study provides the first systematic evidence of the pathology associated with Diplostomum sp. infection in the eye retina of fish (i.e. Arctic charr). Histological sections showed that the trematodes caused mechanical disengagement between the retinal pigmentary epithelium and the neurosensory retina, with damaged cones and rods in the outer segment and epithelium reduced to a single layer of pigmentary cells. The metacercariae were “floating” in possibly fluid-filled vesicles together with several round cells, mostly located in the anterio-dorsal and anterio-ventral areas of the eye near the iris. The round cells may indicate internal retinal damage repair mechanisms, without connections to the general immune system. Metacercariae intestines contained pigmented cellular debris indicating that they feed on retinal epithelium. These retinal lesions may have similar vision effects as focal retinal detachment in vertebrates. Diplostomum metacercaria alters fish visual acuity but may in a lesser degree lead to a severe or total visual impairment because of repairing mechanisms. The pathology in the retina seems thereby to be dependent on fish size, age and dose. Keywords: Helminths, Eyeflukes, Retina, Pathology, Salmonidae, Freshwater Article in Journal/Newspaper Arctic charr Arctic Salvelinus alpinus Directory of Open Access Journals: DOAJ Articles Arctic International Journal for Parasitology: Parasites and Wildlife 7 1 68 74 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Zoology QL1-991 |
spellingShingle |
Zoology QL1-991 F. Padrós R. Knudsen I. Blasco-Costa Histopathological characterisation of retinal lesions associated to Diplostomum species (Platyhelminthes: Trematoda) infection in polymorphic Arctic charr Salvelinus alpinus |
topic_facet |
Zoology QL1-991 |
description |
The eye represents an immune privileged organ where parasites can escape host reactions. This study provides the first systematic evidence of the pathology associated with Diplostomum sp. infection in the eye retina of fish (i.e. Arctic charr). Histological sections showed that the trematodes caused mechanical disengagement between the retinal pigmentary epithelium and the neurosensory retina, with damaged cones and rods in the outer segment and epithelium reduced to a single layer of pigmentary cells. The metacercariae were “floating” in possibly fluid-filled vesicles together with several round cells, mostly located in the anterio-dorsal and anterio-ventral areas of the eye near the iris. The round cells may indicate internal retinal damage repair mechanisms, without connections to the general immune system. Metacercariae intestines contained pigmented cellular debris indicating that they feed on retinal epithelium. These retinal lesions may have similar vision effects as focal retinal detachment in vertebrates. Diplostomum metacercaria alters fish visual acuity but may in a lesser degree lead to a severe or total visual impairment because of repairing mechanisms. The pathology in the retina seems thereby to be dependent on fish size, age and dose. Keywords: Helminths, Eyeflukes, Retina, Pathology, Salmonidae, Freshwater |
format |
Article in Journal/Newspaper |
author |
F. Padrós R. Knudsen I. Blasco-Costa |
author_facet |
F. Padrós R. Knudsen I. Blasco-Costa |
author_sort |
F. Padrós |
title |
Histopathological characterisation of retinal lesions associated to Diplostomum species (Platyhelminthes: Trematoda) infection in polymorphic Arctic charr Salvelinus alpinus |
title_short |
Histopathological characterisation of retinal lesions associated to Diplostomum species (Platyhelminthes: Trematoda) infection in polymorphic Arctic charr Salvelinus alpinus |
title_full |
Histopathological characterisation of retinal lesions associated to Diplostomum species (Platyhelminthes: Trematoda) infection in polymorphic Arctic charr Salvelinus alpinus |
title_fullStr |
Histopathological characterisation of retinal lesions associated to Diplostomum species (Platyhelminthes: Trematoda) infection in polymorphic Arctic charr Salvelinus alpinus |
title_full_unstemmed |
Histopathological characterisation of retinal lesions associated to Diplostomum species (Platyhelminthes: Trematoda) infection in polymorphic Arctic charr Salvelinus alpinus |
title_sort |
histopathological characterisation of retinal lesions associated to diplostomum species (platyhelminthes: trematoda) infection in polymorphic arctic charr salvelinus alpinus |
publisher |
Elsevier |
publishDate |
2018 |
url |
https://doi.org/10.1016/j.ijppaw.2018.01.007 https://doaj.org/article/bafb2cf8f8da4805b8ffe43a719460cc |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic charr Arctic Salvelinus alpinus |
genre_facet |
Arctic charr Arctic Salvelinus alpinus |
op_source |
International Journal for Parasitology: Parasites and Wildlife, Vol 7, Iss 1, Pp 68-74 (2018) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S221322441730130X https://doaj.org/toc/2213-2244 2213-2244 doi:10.1016/j.ijppaw.2018.01.007 https://doaj.org/article/bafb2cf8f8da4805b8ffe43a719460cc |
op_doi |
https://doi.org/10.1016/j.ijppaw.2018.01.007 |
container_title |
International Journal for Parasitology: Parasites and Wildlife |
container_volume |
7 |
container_issue |
1 |
container_start_page |
68 |
op_container_end_page |
74 |
_version_ |
1766304002010513408 |