Synsepalum dulcificum extracts exhibit cytotoxic activity on human colorectal cancer cells and upregulate c-fos and c-jun early apoptotic gene expression

Objective: To explore cytotoxicity of Synsepalum dulcificum (S. dulcificum) Daniell (Sapotaceae) on human colon cancer (HCT-116 and HT-29), human monocytic leukemia (THP-1) and normal (HDFn) cell lines, and its effect on the expression of early apoptotic genes, c-fos and c-jun. Methods: Leaf, stem a...

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Bibliographic Details
Published in:Asian Pacific Journal of Tropical Biomedicine
Main Authors: Jichang Seong, Glenn G Oyong, Esperanza C Cabrera
Format: Article in Journal/Newspaper
Language:English
Published: Wolters Kluwer Medknow Publications 2018
Subjects:
synsepalum dulcificum
colon cancer
monocytic leukemia
apoptosis
c-fos
c-jun
Arctic medicine. Tropical medicine
RC955-962
Biology (General)
QH301-705.5
Arctic
Daniell
Online Access:https://doi.org/10.4103/2221-1691.227999
https://doaj.org/article/bae7520033ce4669adde9c8dcdf4da2a

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