Bufotenine is able to block rabies virus infection in BHK-21 cells

• Published in: Journal of Venomous Animals and Toxins including Tropical Diseases
• Main Authors: Hugo Vigerelli, Juliana Mozer Sciani, Carlos Jared, Marta Maria Antoniazzi, Graciane Maria Medeiros Caporale, Andréa de Cássia Rodrigues da Silva, Daniel C Pimenta
• Format: Article in Journal/Newspaper
• Language: English
• Published: SciELO 2014
• Subjects: Rabies; Rhinella; Bufotenine; Alkaloids; Toxins; Mass spectrometry; Arctic medicine. Tropical medicine; RC955-962; Toxicology. Poisons; RA1190-1270; Zoology; QL1-991; Arctic; Pasteur
• Online Access: https://doi.org/10.1186/1678-9199-20-45; https://doaj.org/article/b94ea0f58f4745beb7a8f8634360d1b4

Background Rabies is a fatal zoonotic neglected disease that occurs in more than 150 countries, and kills more than 55.000 people every year. It is caused by an enveloped single stranded RNA virus that affects the central nervous system, through an infection initiated by the muscular nicotinic acety...