Geographic distribution of human T-lymphotropic virus types 1 and 2 among mothers of newborns tested during neonatal screening, Minas Gerais, Brazil Distribución geográfica del virus linfotrópico de células T humanas tipos 1 y 2 en madres de recién nacidos estudiados en el tamizaje neonatal en Minas Gerais, Brasil
OBJECTIVE: To evaluate the geographic distribution of human T-lymphotropic virus types 1 and 2 (HTLV-1/2) in the State of Minas Gerais, Brazil, in puerperal women whose newborns were tested for HTLV-1/2 during neonatal screening, and to overlap seropositivity with social and economic status determin...
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ftdoajarticles:oai:doaj.org/article:b932f9d85af948b9a0831c85abf09083 2023-05-15T15:19:23+02:00 Geographic distribution of human T-lymphotropic virus types 1 and 2 among mothers of newborns tested during neonatal screening, Minas Gerais, Brazil Distribución geográfica del virus linfotrópico de células T humanas tipos 1 y 2 en madres de recién nacidos estudiados en el tamizaje neonatal en Minas Gerais, Brasil Maísa Aparecida Ribeiro Fernando Augusto Proietti Marina Lobato Martins José Nélio Januário Roberto Vagner Puglia Ladeira Maria de Fátima Oliveira Anna Bárbara de Freitas Carneiro-Proietti 2010-05-01T00:00:00Z https://doaj.org/article/b932f9d85af948b9a0831c85abf09083 EN ES PT eng spa por Pan American Health Organization http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892010000500002 https://doaj.org/toc/1020-4989 https://doaj.org/toc/1680-5348 1020-4989 1680-5348 https://doaj.org/article/b932f9d85af948b9a0831c85abf09083 Revista Panamericana de Salud Pública, Vol 27, Iss 5, Pp 330-337 (2010) Virus linfotrópico de células T humanas tipo 1 virus 2 linfotrópico T humano tamizaje neonatal transmisión vertical de enfermedad infecciosa Brasil Human T-lymphotropic virus 1 human T-lymphotropic virus 2 neonatal screening infectious disease transmission vertical Brazil Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 article 2010 ftdoajarticles 2022-12-31T14:52:10Z OBJECTIVE: To evaluate the geographic distribution of human T-lymphotropic virus types 1 and 2 (HTLV-1/2) in the State of Minas Gerais, Brazil, in puerperal women whose newborns were tested for HTLV-1/2 during neonatal screening, and to overlap seropositivity with social and economic status determinants. METHODS: During September-November 2007, the dry-blood samples taken from newborns on filter paper for routine screening were also tested for maternal IgG anti-HTLV-1/2 antibodies. For reactive samples, the mothers of the newborns had blood drawn to test for these viruses. RESULTS: The study analyzed 55 293 specimens taken from newborns. Of these, 52 (9.4 per 10 000) were reactive and 42 mothers (7.6 per 10 000) were confirmed with HTLV-1/2 infection. HTLV-1/2 geographic distribution was heterogeneous, with a tendency to be higher in the North and North-East parts of Minas Gerais. The highest rates of seropositivity were observed in Vale do Mucuri (55.9 per 10 000) and in Jequitinhonha (16.0 per 10 000), overlapping with the State's worst social and economic indicators. CONCLUSIONS: To our knowledge this was the first time that neonatal screening for HTLV-1/2 was performed in Brazil. This model could be used in other areas with high HTLV-1/2 prevalence rates. The detection of carrier mothers can enable intervention measures, such as providing infant formula to newborns, to be implemented expeditiously to reduce vertical transmission. OBJETIVOS: Evaluar la distribución geográfica del virus linfotrópico de células T humanas tipos 1 y 2 (HTLV-1/2) en el estado de Minas Gerais (Brasil), en mujeres puérperas en cuyos recién nacidos se analizó la presencia del HTLV-1/2 durante las pruebas neonatales de detección sistemática, y superponer la seropositividad con determinantes del estado socioeconómico. MÉTODOS: Entre septiembre y noviembre de 2007, en las muestras de sangre seca extraída a los recién nacidos en papel de filtro para un tamizaje sistemático, se analizaron también los anticuerpos maternos de tipo IgG ... Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic |
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Directory of Open Access Journals: DOAJ Articles |
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ftdoajarticles |
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English Spanish Portuguese |
topic |
Virus linfotrópico de células T humanas tipo 1 virus 2 linfotrópico T humano tamizaje neonatal transmisión vertical de enfermedad infecciosa Brasil Human T-lymphotropic virus 1 human T-lymphotropic virus 2 neonatal screening infectious disease transmission vertical Brazil Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
spellingShingle |
Virus linfotrópico de células T humanas tipo 1 virus 2 linfotrópico T humano tamizaje neonatal transmisión vertical de enfermedad infecciosa Brasil Human T-lymphotropic virus 1 human T-lymphotropic virus 2 neonatal screening infectious disease transmission vertical Brazil Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 Maísa Aparecida Ribeiro Fernando Augusto Proietti Marina Lobato Martins José Nélio Januário Roberto Vagner Puglia Ladeira Maria de Fátima Oliveira Anna Bárbara de Freitas Carneiro-Proietti Geographic distribution of human T-lymphotropic virus types 1 and 2 among mothers of newborns tested during neonatal screening, Minas Gerais, Brazil Distribución geográfica del virus linfotrópico de células T humanas tipos 1 y 2 en madres de recién nacidos estudiados en el tamizaje neonatal en Minas Gerais, Brasil |
topic_facet |
Virus linfotrópico de células T humanas tipo 1 virus 2 linfotrópico T humano tamizaje neonatal transmisión vertical de enfermedad infecciosa Brasil Human T-lymphotropic virus 1 human T-lymphotropic virus 2 neonatal screening infectious disease transmission vertical Brazil Medicine R Arctic medicine. Tropical medicine RC955-962 Public aspects of medicine RA1-1270 |
description |
OBJECTIVE: To evaluate the geographic distribution of human T-lymphotropic virus types 1 and 2 (HTLV-1/2) in the State of Minas Gerais, Brazil, in puerperal women whose newborns were tested for HTLV-1/2 during neonatal screening, and to overlap seropositivity with social and economic status determinants. METHODS: During September-November 2007, the dry-blood samples taken from newborns on filter paper for routine screening were also tested for maternal IgG anti-HTLV-1/2 antibodies. For reactive samples, the mothers of the newborns had blood drawn to test for these viruses. RESULTS: The study analyzed 55 293 specimens taken from newborns. Of these, 52 (9.4 per 10 000) were reactive and 42 mothers (7.6 per 10 000) were confirmed with HTLV-1/2 infection. HTLV-1/2 geographic distribution was heterogeneous, with a tendency to be higher in the North and North-East parts of Minas Gerais. The highest rates of seropositivity were observed in Vale do Mucuri (55.9 per 10 000) and in Jequitinhonha (16.0 per 10 000), overlapping with the State's worst social and economic indicators. CONCLUSIONS: To our knowledge this was the first time that neonatal screening for HTLV-1/2 was performed in Brazil. This model could be used in other areas with high HTLV-1/2 prevalence rates. The detection of carrier mothers can enable intervention measures, such as providing infant formula to newborns, to be implemented expeditiously to reduce vertical transmission. OBJETIVOS: Evaluar la distribución geográfica del virus linfotrópico de células T humanas tipos 1 y 2 (HTLV-1/2) en el estado de Minas Gerais (Brasil), en mujeres puérperas en cuyos recién nacidos se analizó la presencia del HTLV-1/2 durante las pruebas neonatales de detección sistemática, y superponer la seropositividad con determinantes del estado socioeconómico. MÉTODOS: Entre septiembre y noviembre de 2007, en las muestras de sangre seca extraída a los recién nacidos en papel de filtro para un tamizaje sistemático, se analizaron también los anticuerpos maternos de tipo IgG ... |
format |
Article in Journal/Newspaper |
author |
Maísa Aparecida Ribeiro Fernando Augusto Proietti Marina Lobato Martins José Nélio Januário Roberto Vagner Puglia Ladeira Maria de Fátima Oliveira Anna Bárbara de Freitas Carneiro-Proietti |
author_facet |
Maísa Aparecida Ribeiro Fernando Augusto Proietti Marina Lobato Martins José Nélio Januário Roberto Vagner Puglia Ladeira Maria de Fátima Oliveira Anna Bárbara de Freitas Carneiro-Proietti |
author_sort |
Maísa Aparecida Ribeiro |
title |
Geographic distribution of human T-lymphotropic virus types 1 and 2 among mothers of newborns tested during neonatal screening, Minas Gerais, Brazil Distribución geográfica del virus linfotrópico de células T humanas tipos 1 y 2 en madres de recién nacidos estudiados en el tamizaje neonatal en Minas Gerais, Brasil |
title_short |
Geographic distribution of human T-lymphotropic virus types 1 and 2 among mothers of newborns tested during neonatal screening, Minas Gerais, Brazil Distribución geográfica del virus linfotrópico de células T humanas tipos 1 y 2 en madres de recién nacidos estudiados en el tamizaje neonatal en Minas Gerais, Brasil |
title_full |
Geographic distribution of human T-lymphotropic virus types 1 and 2 among mothers of newborns tested during neonatal screening, Minas Gerais, Brazil Distribución geográfica del virus linfotrópico de células T humanas tipos 1 y 2 en madres de recién nacidos estudiados en el tamizaje neonatal en Minas Gerais, Brasil |
title_fullStr |
Geographic distribution of human T-lymphotropic virus types 1 and 2 among mothers of newborns tested during neonatal screening, Minas Gerais, Brazil Distribución geográfica del virus linfotrópico de células T humanas tipos 1 y 2 en madres de recién nacidos estudiados en el tamizaje neonatal en Minas Gerais, Brasil |
title_full_unstemmed |
Geographic distribution of human T-lymphotropic virus types 1 and 2 among mothers of newborns tested during neonatal screening, Minas Gerais, Brazil Distribución geográfica del virus linfotrópico de células T humanas tipos 1 y 2 en madres de recién nacidos estudiados en el tamizaje neonatal en Minas Gerais, Brasil |
title_sort |
geographic distribution of human t-lymphotropic virus types 1 and 2 among mothers of newborns tested during neonatal screening, minas gerais, brazil distribución geográfica del virus linfotrópico de células t humanas tipos 1 y 2 en madres de recién nacidos estudiados en el tamizaje neonatal en minas gerais, brasil |
publisher |
Pan American Health Organization |
publishDate |
2010 |
url |
https://doaj.org/article/b932f9d85af948b9a0831c85abf09083 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista Panamericana de Salud Pública, Vol 27, Iss 5, Pp 330-337 (2010) |
op_relation |
http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892010000500002 https://doaj.org/toc/1020-4989 https://doaj.org/toc/1680-5348 1020-4989 1680-5348 https://doaj.org/article/b932f9d85af948b9a0831c85abf09083 |
_version_ |
1766349563712503808 |