First report of bla GES-1 in Proteus mirabilis clinical isolates

• Published in: Revista da Sociedade Brasileira de Medicina Tropical
• Main Authors: Elizabeth Maria Bispo Beltrão, Érica Maria de Oliveira, Ana Catarina de Souza Lopes
• Format: Article in Journal/Newspaper
• Language: English
• Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2021
• Subjects: Proteus mirabilis; bla GES; bla NDM; Arctic medicine. Tropical medicine; RC955-962; Arctic
• Online Access: https://doi.org/10.1590/0037-8682-0864-2020; https://doaj.org/article/b906185f44204ec78538513949fc62da

Abstract Proteus mirabilis is one of the main pathogens causing urinary tract infections and sepsis. To our knowledge, this is the first report of a P. mirabilis hosting bla GES. The presence of these genes was determined using PCR and sequencing. We identified the presence of bla GES-1 in all three isolates. In addition, we identified the bla KPC-2 and bla NDM-1 genes in the two strains. These data emphasize the importance of monitoring and surveillance of all enterobacteria. The circulation of P. mirabilis strains carrying bla GES-1 constitutes a new scenario of resistance in this species and should be an epidemiological alert for global health.