Toxoplasmosis among pregnant women: High seroprevalence and risk factors in Kinshasa, Democratic Republic of Congo
Objective: To determine the seroprevalence of toxoplasmosis in pregnant women, as well as the proportion of acutely infected and risk factors in the Democratic Republic of Congo. Methods: Thirty maternities in Kinshasa were randomly selected and women attending antenatal consultation were invited to...
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Wolters Kluwer Medknow Publications
2014
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Online Access: | https://doi.org/10.1016/S2221-1691(14)60211-2 https://doaj.org/article/b720ef19f74e499c9ee969d197c1fb23 |
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ftdoajarticles:oai:doaj.org/article:b720ef19f74e499c9ee969d197c1fb23 2023-05-15T15:10:17+02:00 Toxoplasmosis among pregnant women: High seroprevalence and risk factors in Kinshasa, Democratic Republic of Congo Yobi Doudou Piarroux Renaud L'Ollivier Coralie Franck Jacqueline Situakibanza Hypolite Muhindo Hypolite Mitashi Patrick Inocêncio da Luz Raquel Andreia Marc Van Sprundel Boelaert Marleen Jean-Pierre Van Geertruyden Lutumba Pascal 2014-01-01T00:00:00Z https://doi.org/10.1016/S2221-1691(14)60211-2 https://doaj.org/article/b720ef19f74e499c9ee969d197c1fb23 EN eng Wolters Kluwer Medknow Publications http://www.sciencedirect.com/science/article/pii/S2221169114602112 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/S2221-1691(14)60211-2 https://doaj.org/article/b720ef19f74e499c9ee969d197c1fb23 Asian Pacific Journal of Tropical Biomedicine, Vol 4, Iss 1, Pp 69-74 (2014) Seroprevalence Toxoplasmosis Pregnant women Kinshasa Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2014 ftdoajarticles https://doi.org/10.1016/S2221-1691(14)60211-2 2022-12-31T14:49:06Z Objective: To determine the seroprevalence of toxoplasmosis in pregnant women, as well as the proportion of acutely infected and risk factors in the Democratic Republic of Congo. Methods: Thirty maternities in Kinshasa were randomly selected and women attending antenatal consultation were invited to participate. They were interviewed with a structured questionnaire about known risk factors (age, meat consumption, contact with soil, and presence of cat) and a venous blood sample was taken. Sera were analysed for total immunoglobulins (Ig) by VIDAS Toxo Competition using Enzyme Linked Fluorescent Assay. IgM was determined by VIDIA Toxo IgM and IgG avidity by VIDAS Toxo IgG avidity. Results: A total of 781 women were included. Median age was 28 years old (IQR: 8.5). And 627 women (80.3%; 95% CI: 77.5–83.1) were found to be positive to total Ig and 17 out of 387 (4.4%; 95% CI: 2.3–6.4) were positive to IgM. IgG avidity was low for 2 (11.8%) women, intermediate for 2 (11.8%) and high for 13 women (76.4%). There was no statistically significant association between Toxoplasma gondii infection and any risk factors assessed. Conclusion: In Kinshasa, toxoplasmosis endemicity is highly prevalent. One woman out of twenty five had a recent toxoplasmosis infection and 20% were not protected against primo-infection, indicating a need for measures to prevent and control toxoplasmosis during pregnancy. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Asian Pacific Journal of Tropical Biomedicine 4 1 69 74 |
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Directory of Open Access Journals: DOAJ Articles |
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English |
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Seroprevalence Toxoplasmosis Pregnant women Kinshasa Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
spellingShingle |
Seroprevalence Toxoplasmosis Pregnant women Kinshasa Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Yobi Doudou Piarroux Renaud L'Ollivier Coralie Franck Jacqueline Situakibanza Hypolite Muhindo Hypolite Mitashi Patrick Inocêncio da Luz Raquel Andreia Marc Van Sprundel Boelaert Marleen Jean-Pierre Van Geertruyden Lutumba Pascal Toxoplasmosis among pregnant women: High seroprevalence and risk factors in Kinshasa, Democratic Republic of Congo |
topic_facet |
Seroprevalence Toxoplasmosis Pregnant women Kinshasa Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Objective: To determine the seroprevalence of toxoplasmosis in pregnant women, as well as the proportion of acutely infected and risk factors in the Democratic Republic of Congo. Methods: Thirty maternities in Kinshasa were randomly selected and women attending antenatal consultation were invited to participate. They were interviewed with a structured questionnaire about known risk factors (age, meat consumption, contact with soil, and presence of cat) and a venous blood sample was taken. Sera were analysed for total immunoglobulins (Ig) by VIDAS Toxo Competition using Enzyme Linked Fluorescent Assay. IgM was determined by VIDIA Toxo IgM and IgG avidity by VIDAS Toxo IgG avidity. Results: A total of 781 women were included. Median age was 28 years old (IQR: 8.5). And 627 women (80.3%; 95% CI: 77.5–83.1) were found to be positive to total Ig and 17 out of 387 (4.4%; 95% CI: 2.3–6.4) were positive to IgM. IgG avidity was low for 2 (11.8%) women, intermediate for 2 (11.8%) and high for 13 women (76.4%). There was no statistically significant association between Toxoplasma gondii infection and any risk factors assessed. Conclusion: In Kinshasa, toxoplasmosis endemicity is highly prevalent. One woman out of twenty five had a recent toxoplasmosis infection and 20% were not protected against primo-infection, indicating a need for measures to prevent and control toxoplasmosis during pregnancy. |
format |
Article in Journal/Newspaper |
author |
Yobi Doudou Piarroux Renaud L'Ollivier Coralie Franck Jacqueline Situakibanza Hypolite Muhindo Hypolite Mitashi Patrick Inocêncio da Luz Raquel Andreia Marc Van Sprundel Boelaert Marleen Jean-Pierre Van Geertruyden Lutumba Pascal |
author_facet |
Yobi Doudou Piarroux Renaud L'Ollivier Coralie Franck Jacqueline Situakibanza Hypolite Muhindo Hypolite Mitashi Patrick Inocêncio da Luz Raquel Andreia Marc Van Sprundel Boelaert Marleen Jean-Pierre Van Geertruyden Lutumba Pascal |
author_sort |
Yobi Doudou |
title |
Toxoplasmosis among pregnant women: High seroprevalence and risk factors in Kinshasa, Democratic Republic of Congo |
title_short |
Toxoplasmosis among pregnant women: High seroprevalence and risk factors in Kinshasa, Democratic Republic of Congo |
title_full |
Toxoplasmosis among pregnant women: High seroprevalence and risk factors in Kinshasa, Democratic Republic of Congo |
title_fullStr |
Toxoplasmosis among pregnant women: High seroprevalence and risk factors in Kinshasa, Democratic Republic of Congo |
title_full_unstemmed |
Toxoplasmosis among pregnant women: High seroprevalence and risk factors in Kinshasa, Democratic Republic of Congo |
title_sort |
toxoplasmosis among pregnant women: high seroprevalence and risk factors in kinshasa, democratic republic of congo |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2014 |
url |
https://doi.org/10.1016/S2221-1691(14)60211-2 https://doaj.org/article/b720ef19f74e499c9ee969d197c1fb23 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 4, Iss 1, Pp 69-74 (2014) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S2221169114602112 https://doaj.org/toc/2221-1691 2221-1691 doi:10.1016/S2221-1691(14)60211-2 https://doaj.org/article/b720ef19f74e499c9ee969d197c1fb23 |
op_doi |
https://doi.org/10.1016/S2221-1691(14)60211-2 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
4 |
container_issue |
1 |
container_start_page |
69 |
op_container_end_page |
74 |
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1766341329066917888 |