The classification of esterases: an important gene family involved in insecticide resistance - A review
The use of chemical insecticides continues to play a major role in the control of disease vector populations, which is leading to the global dissemination of insecticide resistance. A greater capacity to detoxify insecticides, due to an increase in the expression or activity of three major enzyme fa...
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ftdoajarticles:oai:doaj.org/article:b68b232cdd694bc3b6d1f52403dbbb67 2023-05-15T15:08:28+02:00 The classification of esterases: an important gene family involved in insecticide resistance - A review Isabela Reis Montella Renata Schama Denise Valle 2012-06-01T00:00:00Z https://doi.org/10.1590/S0074-02762012000400001 https://doaj.org/article/b68b232cdd694bc3b6d1f52403dbbb67 EN eng Instituto Oswaldo Cruz, Ministério da Saúde http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000400001&lng=en&tlng=en https://doaj.org/toc/1678-8060 1678-8060 doi:10.1590/S0074-02762012000400001 https://doaj.org/article/b68b232cdd694bc3b6d1f52403dbbb67 Memórias do Instituto Oswaldo Cruz., Vol 107, Iss 4, Pp 437-449 (2012) metabolic resistance carboxylesterase classification history insecticide resistance Arctic medicine. Tropical medicine RC955-962 Microbiology QR1-502 article 2012 ftdoajarticles https://doi.org/10.1590/S0074-02762012000400001 2023-01-08T01:35:51Z The use of chemical insecticides continues to play a major role in the control of disease vector populations, which is leading to the global dissemination of insecticide resistance. A greater capacity to detoxify insecticides, due to an increase in the expression or activity of three major enzyme families, also known as metabolic resistance, is one major resistance mechanisms. The esterase family of enzymes hydrolyse ester bonds, which are present in a wide range of insecticides; therefore, these enzymes may be involved in resistance to the main chemicals employed in control programs. Historically, insecticide resistance has driven research on insect esterases and schemes for their classification. Currently, several different nomenclatures are used to describe the esterases of distinct species and a universal standard classification does not exist. The esterase gene family appears to be rapidly evolving and each insect species has a unique complement of detoxification genes with only a few orthologues across species. The examples listed in this review cover different aspects of their biochemical nature. However, they do not appear to contribute to reliably distinguish among the different resistance mechanisms. Presently, the phylogenetic criterion appears to be the best one for esterase classification. Joint genomic, biochemical and microarray studies will help unravel the classification of this complex gene family. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Memórias do Instituto Oswaldo Cruz 107 4 437 449 |
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Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
metabolic resistance carboxylesterase classification history insecticide resistance Arctic medicine. Tropical medicine RC955-962 Microbiology QR1-502 |
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metabolic resistance carboxylesterase classification history insecticide resistance Arctic medicine. Tropical medicine RC955-962 Microbiology QR1-502 Isabela Reis Montella Renata Schama Denise Valle The classification of esterases: an important gene family involved in insecticide resistance - A review |
topic_facet |
metabolic resistance carboxylesterase classification history insecticide resistance Arctic medicine. Tropical medicine RC955-962 Microbiology QR1-502 |
description |
The use of chemical insecticides continues to play a major role in the control of disease vector populations, which is leading to the global dissemination of insecticide resistance. A greater capacity to detoxify insecticides, due to an increase in the expression or activity of three major enzyme families, also known as metabolic resistance, is one major resistance mechanisms. The esterase family of enzymes hydrolyse ester bonds, which are present in a wide range of insecticides; therefore, these enzymes may be involved in resistance to the main chemicals employed in control programs. Historically, insecticide resistance has driven research on insect esterases and schemes for their classification. Currently, several different nomenclatures are used to describe the esterases of distinct species and a universal standard classification does not exist. The esterase gene family appears to be rapidly evolving and each insect species has a unique complement of detoxification genes with only a few orthologues across species. The examples listed in this review cover different aspects of their biochemical nature. However, they do not appear to contribute to reliably distinguish among the different resistance mechanisms. Presently, the phylogenetic criterion appears to be the best one for esterase classification. Joint genomic, biochemical and microarray studies will help unravel the classification of this complex gene family. |
format |
Article in Journal/Newspaper |
author |
Isabela Reis Montella Renata Schama Denise Valle |
author_facet |
Isabela Reis Montella Renata Schama Denise Valle |
author_sort |
Isabela Reis Montella |
title |
The classification of esterases: an important gene family involved in insecticide resistance - A review |
title_short |
The classification of esterases: an important gene family involved in insecticide resistance - A review |
title_full |
The classification of esterases: an important gene family involved in insecticide resistance - A review |
title_fullStr |
The classification of esterases: an important gene family involved in insecticide resistance - A review |
title_full_unstemmed |
The classification of esterases: an important gene family involved in insecticide resistance - A review |
title_sort |
classification of esterases: an important gene family involved in insecticide resistance - a review |
publisher |
Instituto Oswaldo Cruz, Ministério da Saúde |
publishDate |
2012 |
url |
https://doi.org/10.1590/S0074-02762012000400001 https://doaj.org/article/b68b232cdd694bc3b6d1f52403dbbb67 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Memórias do Instituto Oswaldo Cruz., Vol 107, Iss 4, Pp 437-449 (2012) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000400001&lng=en&tlng=en https://doaj.org/toc/1678-8060 1678-8060 doi:10.1590/S0074-02762012000400001 https://doaj.org/article/b68b232cdd694bc3b6d1f52403dbbb67 |
op_doi |
https://doi.org/10.1590/S0074-02762012000400001 |
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Memórias do Instituto Oswaldo Cruz |
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107 |
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4 |
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437 |
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449 |
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