Bioactivities of extracts from the marine sponge Halichondria panicea
In the present study, we screened the biological activity of extracts from the marine sponge Halichondria panicea collected in the Arabian Sea. Crude toxin was obtained by methanol, chloroform-methanol (2:1) and aqueous extraction. Subsequently, the protein concentration of each crude extract was de...
Published in: | Journal of Venomous Animals and Toxins including Tropical Diseases |
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Language: | English |
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Online Access: | https://doi.org/10.1590/S1678-91992009000300007 https://doaj.org/article/b5899e35bf3d4c9d93cdd9ea86495446 |
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ftdoajarticles:oai:doaj.org/article:b5899e35bf3d4c9d93cdd9ea86495446 2023-05-15T15:03:14+02:00 Bioactivities of extracts from the marine sponge Halichondria panicea GB Purushottama K Venkateshvaran K Pani Prasad P Nalini 2009-01-01T00:00:00Z https://doi.org/10.1590/S1678-91992009000300007 https://doaj.org/article/b5899e35bf3d4c9d93cdd9ea86495446 EN eng SciELO http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992009000300007 https://doaj.org/toc/1678-9199 doi:10.1590/S1678-91992009000300007 1678-9199 https://doaj.org/article/b5899e35bf3d4c9d93cdd9ea86495446 Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 15, Iss 3, Pp 444-459 (2009) Halichondria panicea phagocytosis neuromodulation hemolysis angiogenesis Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 article 2009 ftdoajarticles https://doi.org/10.1590/S1678-91992009000300007 2022-12-31T13:36:30Z In the present study, we screened the biological activity of extracts from the marine sponge Halichondria panicea collected in the Arabian Sea. Crude toxin was obtained by methanol, chloroform-methanol (2:1) and aqueous extraction. Subsequently, the protein concentration of each crude extract was determined. The impact of both sponge methanolic and aqueous extracts was found to increase activities of Na+-K+ ATP-ase and Mg++ ATP-ase. In the case of chloroform-methanol extract, higher concentrations increased acetylcholine esterase (AchE) activity. The methanolic and chloroform-methanol extracts exhibited hemolytic activity on chicken and human erythrocytes, whereas the aqueous extract failed to do so. Methanol and aqueous extracts produced an immunostimulating effect and all extracts revealed angiogenic activity. The aqueous extract yielded nine bands by SDS-PAGE on 12% gel. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Journal of Venomous Animals and Toxins including Tropical Diseases 15 3 444 459 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Halichondria panicea phagocytosis neuromodulation hemolysis angiogenesis Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 |
spellingShingle |
Halichondria panicea phagocytosis neuromodulation hemolysis angiogenesis Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 GB Purushottama K Venkateshvaran K Pani Prasad P Nalini Bioactivities of extracts from the marine sponge Halichondria panicea |
topic_facet |
Halichondria panicea phagocytosis neuromodulation hemolysis angiogenesis Arctic medicine. Tropical medicine RC955-962 Toxicology. Poisons RA1190-1270 Zoology QL1-991 |
description |
In the present study, we screened the biological activity of extracts from the marine sponge Halichondria panicea collected in the Arabian Sea. Crude toxin was obtained by methanol, chloroform-methanol (2:1) and aqueous extraction. Subsequently, the protein concentration of each crude extract was determined. The impact of both sponge methanolic and aqueous extracts was found to increase activities of Na+-K+ ATP-ase and Mg++ ATP-ase. In the case of chloroform-methanol extract, higher concentrations increased acetylcholine esterase (AchE) activity. The methanolic and chloroform-methanol extracts exhibited hemolytic activity on chicken and human erythrocytes, whereas the aqueous extract failed to do so. Methanol and aqueous extracts produced an immunostimulating effect and all extracts revealed angiogenic activity. The aqueous extract yielded nine bands by SDS-PAGE on 12% gel. |
format |
Article in Journal/Newspaper |
author |
GB Purushottama K Venkateshvaran K Pani Prasad P Nalini |
author_facet |
GB Purushottama K Venkateshvaran K Pani Prasad P Nalini |
author_sort |
GB Purushottama |
title |
Bioactivities of extracts from the marine sponge Halichondria panicea |
title_short |
Bioactivities of extracts from the marine sponge Halichondria panicea |
title_full |
Bioactivities of extracts from the marine sponge Halichondria panicea |
title_fullStr |
Bioactivities of extracts from the marine sponge Halichondria panicea |
title_full_unstemmed |
Bioactivities of extracts from the marine sponge Halichondria panicea |
title_sort |
bioactivities of extracts from the marine sponge halichondria panicea |
publisher |
SciELO |
publishDate |
2009 |
url |
https://doi.org/10.1590/S1678-91992009000300007 https://doaj.org/article/b5899e35bf3d4c9d93cdd9ea86495446 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 15, Iss 3, Pp 444-459 (2009) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992009000300007 https://doaj.org/toc/1678-9199 doi:10.1590/S1678-91992009000300007 1678-9199 https://doaj.org/article/b5899e35bf3d4c9d93cdd9ea86495446 |
op_doi |
https://doi.org/10.1590/S1678-91992009000300007 |
container_title |
Journal of Venomous Animals and Toxins including Tropical Diseases |
container_volume |
15 |
container_issue |
3 |
container_start_page |
444 |
op_container_end_page |
459 |
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1766335118595588096 |