Case report: Canine distemper virus infection as a cause of central nervous system disease in a Eurasian lynx (Lynx lynx)
The Eurasian lynx (Lynx lynx) represents an endangered species with only small populations remaining in Central Europe. Knowledge about the threat posed by potential infectious agents to these animals is crucial for informing ongoing protection measures. Canine distemper virus (CDV) is known to have...
Published in: | Frontiers in Veterinary Science |
---|---|
Main Authors: | , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Frontiers Media S.A.
2023
|
Subjects: | |
Online Access: | https://doi.org/10.3389/fvets.2023.1251018 https://doaj.org/article/b4ca1e940e764b55bbad2c00c473473d |
id |
ftdoajarticles:oai:doaj.org/article:b4ca1e940e764b55bbad2c00c473473d |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:b4ca1e940e764b55bbad2c00c473473d 2023-09-05T13:24:03+02:00 Case report: Canine distemper virus infection as a cause of central nervous system disease in a Eurasian lynx (Lynx lynx) Mara Sophie Lombardo Monica Mirolo Florian Brandes Albert D. M. E. Osterhaus Karolin Schütte Martin Ludlow Michael Barkhoff Wolfgang Baumgärtner Christina Puff 2023-08-01T00:00:00Z https://doi.org/10.3389/fvets.2023.1251018 https://doaj.org/article/b4ca1e940e764b55bbad2c00c473473d EN eng Frontiers Media S.A. https://www.frontiersin.org/articles/10.3389/fvets.2023.1251018/full https://doaj.org/toc/2297-1769 2297-1769 doi:10.3389/fvets.2023.1251018 https://doaj.org/article/b4ca1e940e764b55bbad2c00c473473d Frontiers in Veterinary Science, Vol 10 (2023) computer tomography encephalitis endangered species viral infection wildlife Veterinary medicine SF600-1100 article 2023 ftdoajarticles https://doi.org/10.3389/fvets.2023.1251018 2023-08-20T00:35:31Z The Eurasian lynx (Lynx lynx) represents an endangered species with only small populations remaining in Central Europe. Knowledge about the threat posed by potential infectious agents to these animals is crucial for informing ongoing protection measures. Canine distemper virus (CDV) is known to have a wide host range with infection reported in many mammalian species including several lynx species (Lynx pardinus, Lynx canadensis, Lynx rufus), but is an extremely rare finding in the Eurasian lynx. The present report describes a case of a Eurasian lynx showing central nervous signs, including apathy and ataxia. A CT scan revealed multiple hypodense areas in different localizations within the brain as well as enlarged liquid filled areas, leading to the suspicion of a degenerative process. Due to clinical deterioration, the animal was euthanized and submitted for macroscopical and histological investigations. Histological investigations revealed multifocal demyelinations in the cerebellum, brain stem and cervical spinal cord as well as a multifocal, perivascular, lymphohistiocytic meningoencephalitis. A CDV infection was confirmed by immunohistochemistry and RT-PCR analyses. This CDV infection of a Eurasian lynx resembles a classical chronic manifestation of distemper in dogs and highlights the threat posed by canine distemper to this species. Article in Journal/Newspaper Lynx Lynx lynx lynx Directory of Open Access Journals: DOAJ Articles Frontiers in Veterinary Science 10 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
computer tomography encephalitis endangered species viral infection wildlife Veterinary medicine SF600-1100 |
spellingShingle |
computer tomography encephalitis endangered species viral infection wildlife Veterinary medicine SF600-1100 Mara Sophie Lombardo Monica Mirolo Florian Brandes Albert D. M. E. Osterhaus Karolin Schütte Martin Ludlow Michael Barkhoff Wolfgang Baumgärtner Christina Puff Case report: Canine distemper virus infection as a cause of central nervous system disease in a Eurasian lynx (Lynx lynx) |
topic_facet |
computer tomography encephalitis endangered species viral infection wildlife Veterinary medicine SF600-1100 |
description |
The Eurasian lynx (Lynx lynx) represents an endangered species with only small populations remaining in Central Europe. Knowledge about the threat posed by potential infectious agents to these animals is crucial for informing ongoing protection measures. Canine distemper virus (CDV) is known to have a wide host range with infection reported in many mammalian species including several lynx species (Lynx pardinus, Lynx canadensis, Lynx rufus), but is an extremely rare finding in the Eurasian lynx. The present report describes a case of a Eurasian lynx showing central nervous signs, including apathy and ataxia. A CT scan revealed multiple hypodense areas in different localizations within the brain as well as enlarged liquid filled areas, leading to the suspicion of a degenerative process. Due to clinical deterioration, the animal was euthanized and submitted for macroscopical and histological investigations. Histological investigations revealed multifocal demyelinations in the cerebellum, brain stem and cervical spinal cord as well as a multifocal, perivascular, lymphohistiocytic meningoencephalitis. A CDV infection was confirmed by immunohistochemistry and RT-PCR analyses. This CDV infection of a Eurasian lynx resembles a classical chronic manifestation of distemper in dogs and highlights the threat posed by canine distemper to this species. |
format |
Article in Journal/Newspaper |
author |
Mara Sophie Lombardo Monica Mirolo Florian Brandes Albert D. M. E. Osterhaus Karolin Schütte Martin Ludlow Michael Barkhoff Wolfgang Baumgärtner Christina Puff |
author_facet |
Mara Sophie Lombardo Monica Mirolo Florian Brandes Albert D. M. E. Osterhaus Karolin Schütte Martin Ludlow Michael Barkhoff Wolfgang Baumgärtner Christina Puff |
author_sort |
Mara Sophie Lombardo |
title |
Case report: Canine distemper virus infection as a cause of central nervous system disease in a Eurasian lynx (Lynx lynx) |
title_short |
Case report: Canine distemper virus infection as a cause of central nervous system disease in a Eurasian lynx (Lynx lynx) |
title_full |
Case report: Canine distemper virus infection as a cause of central nervous system disease in a Eurasian lynx (Lynx lynx) |
title_fullStr |
Case report: Canine distemper virus infection as a cause of central nervous system disease in a Eurasian lynx (Lynx lynx) |
title_full_unstemmed |
Case report: Canine distemper virus infection as a cause of central nervous system disease in a Eurasian lynx (Lynx lynx) |
title_sort |
case report: canine distemper virus infection as a cause of central nervous system disease in a eurasian lynx (lynx lynx) |
publisher |
Frontiers Media S.A. |
publishDate |
2023 |
url |
https://doi.org/10.3389/fvets.2023.1251018 https://doaj.org/article/b4ca1e940e764b55bbad2c00c473473d |
genre |
Lynx Lynx lynx lynx |
genre_facet |
Lynx Lynx lynx lynx |
op_source |
Frontiers in Veterinary Science, Vol 10 (2023) |
op_relation |
https://www.frontiersin.org/articles/10.3389/fvets.2023.1251018/full https://doaj.org/toc/2297-1769 2297-1769 doi:10.3389/fvets.2023.1251018 https://doaj.org/article/b4ca1e940e764b55bbad2c00c473473d |
op_doi |
https://doi.org/10.3389/fvets.2023.1251018 |
container_title |
Frontiers in Veterinary Science |
container_volume |
10 |
_version_ |
1776204624108191744 |