Phytochemical analyses, antimicrobial and antioxidant activities of stem bark extracts of Distemonanthus benthamianus H. Baill. and fruit extracts of Solanum torvum Sw. from Gabon
Objective: To evaluate the phytochemical constituents, antimicrobial and antioxidant activities of the extracts of Distemonanthus benthamianus (D. benthamianus) stem bark and Solanum torvum (S. torvum) fruit which have been used as traditional medicinal herbs in Gabon. Methods: Plant extracts were s...
Published in: | Asian Pacific Journal of Tropical Biomedicine |
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Wolters Kluwer Medknow Publications
2019
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Online Access: | https://doi.org/10.4103/2221-1691.259001 https://doaj.org/article/b4bea74c77b0435f8d50e7ef5f46d544 |
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ftdoajarticles:oai:doaj.org/article:b4bea74c77b0435f8d50e7ef5f46d544 2023-05-15T15:09:19+02:00 Phytochemical analyses, antimicrobial and antioxidant activities of stem bark extracts of Distemonanthus benthamianus H. Baill. and fruit extracts of Solanum torvum Sw. from Gabon Cédric Sima Obiang Rick Léonid Ngoua Meye Misso Guy Roger Ndong Atome Joseph Privat Ondo Louis Clément Obame Engonga Edouard Nsi Emvo 2019-01-01T00:00:00Z https://doi.org/10.4103/2221-1691.259001 https://doaj.org/article/b4bea74c77b0435f8d50e7ef5f46d544 EN eng Wolters Kluwer Medknow Publications http://www.apjtb.org/article.asp?issn=2221-1691;year=2019;volume=9;issue=5;spage=209;epage=216;aulast=Obiang https://doaj.org/toc/2221-1691 2221-1691 doi:10.4103/2221-1691.259001 https://doaj.org/article/b4bea74c77b0435f8d50e7ef5f46d544 Asian Pacific Journal of Tropical Biomedicine, Vol 9, Iss 5, Pp 209-216 (2019) antioxidants phytochemical antimicrobial distemonanthus benthamianus solanum torvum Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 article 2019 ftdoajarticles https://doi.org/10.4103/2221-1691.259001 2022-12-31T09:50:15Z Objective: To evaluate the phytochemical constituents, antimicrobial and antioxidant activities of the extracts of Distemonanthus benthamianus (D. benthamianus) stem bark and Solanum torvum (S. torvum) fruit which have been used as traditional medicinal herbs in Gabon. Methods: Plant extracts were subjected to a qualitative study (phytochemical screening) and a quantitative (dosing) study of secondary metabolites. Antioxidant activity was tested by 1,1- diphenyl-2-picrylhydrazyl and 2,2’-azino-bis 3-ethylbenzothiazoline-6-sulfonic acid assay. Bacteria and fungi susceptibility tests were performed on Mueller Hinton medium and solid Sabouraud, respectively, using the diffusion method, while minimum inhibitory concentration, minimum fungicidal concentration and minimum bactericidal concentration were evaluated by microdilution method. Results: The total phenol and tannin contents were significantly higher in the water-ethanol extract compared to the other extracts of D. benthamianus and S. torvum. The water-ethanol and water-acetone extracts showed significantly higher antioxidant activity than the aqueous extracts of the two medicinal plants. However, the extracts presented weak antioxidant activities compared to standards (Vitamin C, BHA). The water-acetone and water-ethanol extracts of S. torvum showed the highest antimicrobial activity against Bacillus cereus LMG 13569 BHI, Shigella dysenteriae 5451 CIP, Shigella dysenteriae and Neisseria gonorrhoeae. Conclusions: Our results show that D. benthamianus and S. torvum can be promising sources of natural products with potential antimicrobial and antioxidant activities. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Mueller ENVELOPE(55.533,55.533,-66.917,-66.917) Asian Pacific Journal of Tropical Biomedicine 9 5 209 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
antioxidants phytochemical antimicrobial distemonanthus benthamianus solanum torvum Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
spellingShingle |
antioxidants phytochemical antimicrobial distemonanthus benthamianus solanum torvum Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 Cédric Sima Obiang Rick Léonid Ngoua Meye Misso Guy Roger Ndong Atome Joseph Privat Ondo Louis Clément Obame Engonga Edouard Nsi Emvo Phytochemical analyses, antimicrobial and antioxidant activities of stem bark extracts of Distemonanthus benthamianus H. Baill. and fruit extracts of Solanum torvum Sw. from Gabon |
topic_facet |
antioxidants phytochemical antimicrobial distemonanthus benthamianus solanum torvum Arctic medicine. Tropical medicine RC955-962 Biology (General) QH301-705.5 |
description |
Objective: To evaluate the phytochemical constituents, antimicrobial and antioxidant activities of the extracts of Distemonanthus benthamianus (D. benthamianus) stem bark and Solanum torvum (S. torvum) fruit which have been used as traditional medicinal herbs in Gabon. Methods: Plant extracts were subjected to a qualitative study (phytochemical screening) and a quantitative (dosing) study of secondary metabolites. Antioxidant activity was tested by 1,1- diphenyl-2-picrylhydrazyl and 2,2’-azino-bis 3-ethylbenzothiazoline-6-sulfonic acid assay. Bacteria and fungi susceptibility tests were performed on Mueller Hinton medium and solid Sabouraud, respectively, using the diffusion method, while minimum inhibitory concentration, minimum fungicidal concentration and minimum bactericidal concentration were evaluated by microdilution method. Results: The total phenol and tannin contents were significantly higher in the water-ethanol extract compared to the other extracts of D. benthamianus and S. torvum. The water-ethanol and water-acetone extracts showed significantly higher antioxidant activity than the aqueous extracts of the two medicinal plants. However, the extracts presented weak antioxidant activities compared to standards (Vitamin C, BHA). The water-acetone and water-ethanol extracts of S. torvum showed the highest antimicrobial activity against Bacillus cereus LMG 13569 BHI, Shigella dysenteriae 5451 CIP, Shigella dysenteriae and Neisseria gonorrhoeae. Conclusions: Our results show that D. benthamianus and S. torvum can be promising sources of natural products with potential antimicrobial and antioxidant activities. |
format |
Article in Journal/Newspaper |
author |
Cédric Sima Obiang Rick Léonid Ngoua Meye Misso Guy Roger Ndong Atome Joseph Privat Ondo Louis Clément Obame Engonga Edouard Nsi Emvo |
author_facet |
Cédric Sima Obiang Rick Léonid Ngoua Meye Misso Guy Roger Ndong Atome Joseph Privat Ondo Louis Clément Obame Engonga Edouard Nsi Emvo |
author_sort |
Cédric Sima Obiang |
title |
Phytochemical analyses, antimicrobial and antioxidant activities of stem bark extracts of Distemonanthus benthamianus H. Baill. and fruit extracts of Solanum torvum Sw. from Gabon |
title_short |
Phytochemical analyses, antimicrobial and antioxidant activities of stem bark extracts of Distemonanthus benthamianus H. Baill. and fruit extracts of Solanum torvum Sw. from Gabon |
title_full |
Phytochemical analyses, antimicrobial and antioxidant activities of stem bark extracts of Distemonanthus benthamianus H. Baill. and fruit extracts of Solanum torvum Sw. from Gabon |
title_fullStr |
Phytochemical analyses, antimicrobial and antioxidant activities of stem bark extracts of Distemonanthus benthamianus H. Baill. and fruit extracts of Solanum torvum Sw. from Gabon |
title_full_unstemmed |
Phytochemical analyses, antimicrobial and antioxidant activities of stem bark extracts of Distemonanthus benthamianus H. Baill. and fruit extracts of Solanum torvum Sw. from Gabon |
title_sort |
phytochemical analyses, antimicrobial and antioxidant activities of stem bark extracts of distemonanthus benthamianus h. baill. and fruit extracts of solanum torvum sw. from gabon |
publisher |
Wolters Kluwer Medknow Publications |
publishDate |
2019 |
url |
https://doi.org/10.4103/2221-1691.259001 https://doaj.org/article/b4bea74c77b0435f8d50e7ef5f46d544 |
long_lat |
ENVELOPE(55.533,55.533,-66.917,-66.917) |
geographic |
Arctic Mueller |
geographic_facet |
Arctic Mueller |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Asian Pacific Journal of Tropical Biomedicine, Vol 9, Iss 5, Pp 209-216 (2019) |
op_relation |
http://www.apjtb.org/article.asp?issn=2221-1691;year=2019;volume=9;issue=5;spage=209;epage=216;aulast=Obiang https://doaj.org/toc/2221-1691 2221-1691 doi:10.4103/2221-1691.259001 https://doaj.org/article/b4bea74c77b0435f8d50e7ef5f46d544 |
op_doi |
https://doi.org/10.4103/2221-1691.259001 |
container_title |
Asian Pacific Journal of Tropical Biomedicine |
container_volume |
9 |
container_issue |
5 |
container_start_page |
209 |
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1766340518166396928 |