Rodent Virus Diversity and Differentiation across Post-Katrina New Orleans
Concern about elevated disease risk following disasters has been growing with the progression of global trends in urbanization and climate, in part because shifts in socioecological conditions can promote greater human contact with pathogen reservoirs in cities. Remarkably little is known, however,...
Published in: | Sustainability |
---|---|
Main Authors: | , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
MDPI AG
2021
|
Subjects: | |
Online Access: | https://doi.org/10.3390/su13148034 https://doaj.org/article/b3d1c80f76964d39bd8ad0dad3c0520e |
id |
ftdoajarticles:oai:doaj.org/article:b3d1c80f76964d39bd8ad0dad3c0520e |
---|---|
record_format |
openpolar |
spelling |
ftdoajarticles:oai:doaj.org/article:b3d1c80f76964d39bd8ad0dad3c0520e 2023-05-15T18:05:31+02:00 Rodent Virus Diversity and Differentiation across Post-Katrina New Orleans Anna C. Peterson Himanshu Sharma Arvind Kumar Bruno M. Ghersi Scott J. Emrich Kurt J. Vandegrift Amit Kapoor Michael J. Blum 2021-07-01T00:00:00Z https://doi.org/10.3390/su13148034 https://doaj.org/article/b3d1c80f76964d39bd8ad0dad3c0520e EN eng MDPI AG https://www.mdpi.com/2071-1050/13/14/8034 https://doaj.org/toc/2071-1050 doi:10.3390/su13148034 2071-1050 https://doaj.org/article/b3d1c80f76964d39bd8ad0dad3c0520e Sustainability, Vol 13, Iss 8034, p 8034 (2021) abandonment disaster emerging infectious disease pathogens surveillance urban Environmental effects of industries and plants TD194-195 Renewable energy sources TJ807-830 Environmental sciences GE1-350 article 2021 ftdoajarticles https://doi.org/10.3390/su13148034 2022-12-31T16:19:03Z Concern about elevated disease risk following disasters has been growing with the progression of global trends in urbanization and climate, in part because shifts in socioecological conditions can promote greater human contact with pathogen reservoirs in cities. Remarkably little is known, however, about the diversity and distributions of pathogens carried by commensal reservoirs across disaster-affected urban landscapes. To address this deficit, we characterized the assemblage structure of viruses in the serum of three widespread commensal rodents ( Rattus norvegicus , Rattus rattus , and Mus musculus ) that were trapped in New Orleans (LA, USA) following Hurricane Katrina. We assessed virus diversity and differentiation according to host species identity, co-occurrence and abundance, as well as prevailing landscape features known to shape urban rodent assemblages. We detected ≥34 viruses in total, including several pathogens of concern, through metagenomic analysis of serum taken from ≥149 individuals of each host species. We found that virus richness as well as assemblage composition and spatial differentiation differed by host species. Notably, we detected associations with host species co-occurrence and abundance, and while we found that assemblage structure varied by study area, we did not detect strong associations with landscape features known to influence rodent hosts. Evidence that virus diversity and assemblage structure reflect host identity more so than other factors indicates that biotic benchmarks might serve as prognostic indicators of post-disaster pathogen exposure risk in cities worldwide. Article in Journal/Newspaper Rattus rattus Directory of Open Access Journals: DOAJ Articles Orleans ENVELOPE(-60.667,-60.667,-63.950,-63.950) Sustainability 13 14 8034 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
abandonment disaster emerging infectious disease pathogens surveillance urban Environmental effects of industries and plants TD194-195 Renewable energy sources TJ807-830 Environmental sciences GE1-350 |
spellingShingle |
abandonment disaster emerging infectious disease pathogens surveillance urban Environmental effects of industries and plants TD194-195 Renewable energy sources TJ807-830 Environmental sciences GE1-350 Anna C. Peterson Himanshu Sharma Arvind Kumar Bruno M. Ghersi Scott J. Emrich Kurt J. Vandegrift Amit Kapoor Michael J. Blum Rodent Virus Diversity and Differentiation across Post-Katrina New Orleans |
topic_facet |
abandonment disaster emerging infectious disease pathogens surveillance urban Environmental effects of industries and plants TD194-195 Renewable energy sources TJ807-830 Environmental sciences GE1-350 |
description |
Concern about elevated disease risk following disasters has been growing with the progression of global trends in urbanization and climate, in part because shifts in socioecological conditions can promote greater human contact with pathogen reservoirs in cities. Remarkably little is known, however, about the diversity and distributions of pathogens carried by commensal reservoirs across disaster-affected urban landscapes. To address this deficit, we characterized the assemblage structure of viruses in the serum of three widespread commensal rodents ( Rattus norvegicus , Rattus rattus , and Mus musculus ) that were trapped in New Orleans (LA, USA) following Hurricane Katrina. We assessed virus diversity and differentiation according to host species identity, co-occurrence and abundance, as well as prevailing landscape features known to shape urban rodent assemblages. We detected ≥34 viruses in total, including several pathogens of concern, through metagenomic analysis of serum taken from ≥149 individuals of each host species. We found that virus richness as well as assemblage composition and spatial differentiation differed by host species. Notably, we detected associations with host species co-occurrence and abundance, and while we found that assemblage structure varied by study area, we did not detect strong associations with landscape features known to influence rodent hosts. Evidence that virus diversity and assemblage structure reflect host identity more so than other factors indicates that biotic benchmarks might serve as prognostic indicators of post-disaster pathogen exposure risk in cities worldwide. |
format |
Article in Journal/Newspaper |
author |
Anna C. Peterson Himanshu Sharma Arvind Kumar Bruno M. Ghersi Scott J. Emrich Kurt J. Vandegrift Amit Kapoor Michael J. Blum |
author_facet |
Anna C. Peterson Himanshu Sharma Arvind Kumar Bruno M. Ghersi Scott J. Emrich Kurt J. Vandegrift Amit Kapoor Michael J. Blum |
author_sort |
Anna C. Peterson |
title |
Rodent Virus Diversity and Differentiation across Post-Katrina New Orleans |
title_short |
Rodent Virus Diversity and Differentiation across Post-Katrina New Orleans |
title_full |
Rodent Virus Diversity and Differentiation across Post-Katrina New Orleans |
title_fullStr |
Rodent Virus Diversity and Differentiation across Post-Katrina New Orleans |
title_full_unstemmed |
Rodent Virus Diversity and Differentiation across Post-Katrina New Orleans |
title_sort |
rodent virus diversity and differentiation across post-katrina new orleans |
publisher |
MDPI AG |
publishDate |
2021 |
url |
https://doi.org/10.3390/su13148034 https://doaj.org/article/b3d1c80f76964d39bd8ad0dad3c0520e |
long_lat |
ENVELOPE(-60.667,-60.667,-63.950,-63.950) |
geographic |
Orleans |
geographic_facet |
Orleans |
genre |
Rattus rattus |
genre_facet |
Rattus rattus |
op_source |
Sustainability, Vol 13, Iss 8034, p 8034 (2021) |
op_relation |
https://www.mdpi.com/2071-1050/13/14/8034 https://doaj.org/toc/2071-1050 doi:10.3390/su13148034 2071-1050 https://doaj.org/article/b3d1c80f76964d39bd8ad0dad3c0520e |
op_doi |
https://doi.org/10.3390/su13148034 |
container_title |
Sustainability |
container_volume |
13 |
container_issue |
14 |
container_start_page |
8034 |
_version_ |
1766176989686792192 |