Implementation and evaluation of a quality and safety tool for ambulatory strongyloidiasis patients at high risk of adverse outcome
Abstract Background Strongyloidiasis is a common infection in Canadian migrants that can cause life-threatening hyperinfection in immunosuppressed hosts. We designed and implemented a safety tool to guide management of patients with Strongyloides in order to prevent adverse outcomes. Methods: Patien...
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ftdoajarticles:oai:doaj.org/article:b25c0cfe4c7f45f8af96a00c6bf36729 2023-05-15T15:09:03+02:00 Implementation and evaluation of a quality and safety tool for ambulatory strongyloidiasis patients at high risk of adverse outcome Sabrina H. M. Yeung Omar Mourad Michael Klowak Adrienne J. Showler Stefanie Klowak Andrea K. Boggild 2019-04-01T00:00:00Z https://doi.org/10.1186/s40794-019-0080-1 https://doaj.org/article/b25c0cfe4c7f45f8af96a00c6bf36729 EN eng BMC http://link.springer.com/article/10.1186/s40794-019-0080-1 https://doaj.org/toc/2055-0936 doi:10.1186/s40794-019-0080-1 2055-0936 https://doaj.org/article/b25c0cfe4c7f45f8af96a00c6bf36729 Tropical Diseases, Travel Medicine and Vaccines, Vol 5, Iss 1, Pp 1-8 (2019) Quality improvement Patient safety Strongyloidiasis Soil-transmitted helminths Neglected tropical diseases Arctic medicine. Tropical medicine RC955-962 article 2019 ftdoajarticles https://doi.org/10.1186/s40794-019-0080-1 2022-12-31T01:14:56Z Abstract Background Strongyloidiasis is a common infection in Canadian migrants that can cause life-threatening hyperinfection in immunosuppressed hosts. We designed and implemented a safety tool to guide management of patients with Strongyloides in order to prevent adverse outcomes. Methods: Patients treated at our centre for strongyloidiasis from January 1, 2013 to December 31, 2015 were identified through our ivermectin access log. Patients were categorized into pre-implementation and post-implementation groups. A retrospective chart review for predefined variables was conducted. Results Of 37 patients with strongyloidiasis, 26 were in the pre-implementation group and 11 were in the post-implementation group. Documented seroreversion (positive to negative) occurred in 42.1% of patients pre-implementation and 62.5% of patients post-implementation (p = 0.420). Documented stool clearance occurred in 80.0% of patients pre-implementation and 100.0% of patients post-implementation (p = 1.000). More patients were screened for HTLV-1 coinfection post-implementation (80.0%) versus pre-implementation (30.8%) (p = 0.011). Loss to follow-up after treatment occurred in 23.1% of patients pre-implementation and 20.0% of patients post-implementation (p = 1.000). Conclusions The safety tool may be useful in the treatment of patients with strongyloidiasis to improve documentation of patient outcomes and standardize care. Future research should include a powered prospective study. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Tropical Diseases, Travel Medicine and Vaccines 5 1 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Quality improvement Patient safety Strongyloidiasis Soil-transmitted helminths Neglected tropical diseases Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Quality improvement Patient safety Strongyloidiasis Soil-transmitted helminths Neglected tropical diseases Arctic medicine. Tropical medicine RC955-962 Sabrina H. M. Yeung Omar Mourad Michael Klowak Adrienne J. Showler Stefanie Klowak Andrea K. Boggild Implementation and evaluation of a quality and safety tool for ambulatory strongyloidiasis patients at high risk of adverse outcome |
topic_facet |
Quality improvement Patient safety Strongyloidiasis Soil-transmitted helminths Neglected tropical diseases Arctic medicine. Tropical medicine RC955-962 |
description |
Abstract Background Strongyloidiasis is a common infection in Canadian migrants that can cause life-threatening hyperinfection in immunosuppressed hosts. We designed and implemented a safety tool to guide management of patients with Strongyloides in order to prevent adverse outcomes. Methods: Patients treated at our centre for strongyloidiasis from January 1, 2013 to December 31, 2015 were identified through our ivermectin access log. Patients were categorized into pre-implementation and post-implementation groups. A retrospective chart review for predefined variables was conducted. Results Of 37 patients with strongyloidiasis, 26 were in the pre-implementation group and 11 were in the post-implementation group. Documented seroreversion (positive to negative) occurred in 42.1% of patients pre-implementation and 62.5% of patients post-implementation (p = 0.420). Documented stool clearance occurred in 80.0% of patients pre-implementation and 100.0% of patients post-implementation (p = 1.000). More patients were screened for HTLV-1 coinfection post-implementation (80.0%) versus pre-implementation (30.8%) (p = 0.011). Loss to follow-up after treatment occurred in 23.1% of patients pre-implementation and 20.0% of patients post-implementation (p = 1.000). Conclusions The safety tool may be useful in the treatment of patients with strongyloidiasis to improve documentation of patient outcomes and standardize care. Future research should include a powered prospective study. |
format |
Article in Journal/Newspaper |
author |
Sabrina H. M. Yeung Omar Mourad Michael Klowak Adrienne J. Showler Stefanie Klowak Andrea K. Boggild |
author_facet |
Sabrina H. M. Yeung Omar Mourad Michael Klowak Adrienne J. Showler Stefanie Klowak Andrea K. Boggild |
author_sort |
Sabrina H. M. Yeung |
title |
Implementation and evaluation of a quality and safety tool for ambulatory strongyloidiasis patients at high risk of adverse outcome |
title_short |
Implementation and evaluation of a quality and safety tool for ambulatory strongyloidiasis patients at high risk of adverse outcome |
title_full |
Implementation and evaluation of a quality and safety tool for ambulatory strongyloidiasis patients at high risk of adverse outcome |
title_fullStr |
Implementation and evaluation of a quality and safety tool for ambulatory strongyloidiasis patients at high risk of adverse outcome |
title_full_unstemmed |
Implementation and evaluation of a quality and safety tool for ambulatory strongyloidiasis patients at high risk of adverse outcome |
title_sort |
implementation and evaluation of a quality and safety tool for ambulatory strongyloidiasis patients at high risk of adverse outcome |
publisher |
BMC |
publishDate |
2019 |
url |
https://doi.org/10.1186/s40794-019-0080-1 https://doaj.org/article/b25c0cfe4c7f45f8af96a00c6bf36729 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Tropical Diseases, Travel Medicine and Vaccines, Vol 5, Iss 1, Pp 1-8 (2019) |
op_relation |
http://link.springer.com/article/10.1186/s40794-019-0080-1 https://doaj.org/toc/2055-0936 doi:10.1186/s40794-019-0080-1 2055-0936 https://doaj.org/article/b25c0cfe4c7f45f8af96a00c6bf36729 |
op_doi |
https://doi.org/10.1186/s40794-019-0080-1 |
container_title |
Tropical Diseases, Travel Medicine and Vaccines |
container_volume |
5 |
container_issue |
1 |
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1766340280410177536 |