Histomorphologic and Immunohistochemical Characterization of a Cardiac Purkinjeoma in a Bearded Seal (Erignathus barbatus)
The most common cardiac tumors of heart muscle are rhabdomyomas, solitary or multiple benign tumors of striated muscle origin. While cardiac rhabdomyomas are well described in human medical literature, limited information depicting the occurrence of cardiac rhabdomyomas in veterinary species exists....
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ftdoajarticles:oai:doaj.org/article:b2284d3ca3eb419bb0061913a60460e9 2024-09-15T17:58:19+00:00 Histomorphologic and Immunohistochemical Characterization of a Cardiac Purkinjeoma in a Bearded Seal (Erignathus barbatus) G. Krafsur E. J. Ehrhart J. Ramos-Vara G. Mason F. Sarren B. Adams C. Hanns T. Spraker C. Duncan 2014-01-01T00:00:00Z https://doi.org/10.1155/2014/103279 https://doaj.org/article/b2284d3ca3eb419bb0061913a60460e9 EN eng Wiley http://dx.doi.org/10.1155/2014/103279 https://doaj.org/toc/2090-7001 https://doaj.org/toc/2090-701X 2090-7001 2090-701X doi:10.1155/2014/103279 https://doaj.org/article/b2284d3ca3eb419bb0061913a60460e9 Case Reports in Veterinary Medicine, Vol 2014 (2014) Veterinary medicine SF600-1100 article 2014 ftdoajarticles https://doi.org/10.1155/2014/103279 2024-08-05T17:48:36Z The most common cardiac tumors of heart muscle are rhabdomyomas, solitary or multiple benign tumors of striated muscle origin. While cardiac rhabdomyomas are well described in human medical literature, limited information depicting the occurrence of cardiac rhabdomyomas in veterinary species exists. A case of multiple firm white nonencapsulated nodules in the heart of a bearded seal is described. Microscopic findings included cytoplasmic vacuolization with formation of spider cells, glycogen vacuoles, and striated myofibrils. These cells expressed immunoreactivity for neuron-specific enolase and protein gene product 9.5, a marker for neuronal tissue and Purkinje fiber cells. Immunoreactivity for protein gene product 9.5 along with other microscopic findings substantiates Purkinje fiber cell origin of the cardiac rhabdomyoma in the bearded seal and use of the term purkinjeoma to describe this lesion. Article in Journal/Newspaper bearded seal Erignathus barbatus Directory of Open Access Journals: DOAJ Articles Case Reports in Veterinary Medicine 2014 1 4 |
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Directory of Open Access Journals: DOAJ Articles |
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English |
topic |
Veterinary medicine SF600-1100 |
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Veterinary medicine SF600-1100 G. Krafsur E. J. Ehrhart J. Ramos-Vara G. Mason F. Sarren B. Adams C. Hanns T. Spraker C. Duncan Histomorphologic and Immunohistochemical Characterization of a Cardiac Purkinjeoma in a Bearded Seal (Erignathus barbatus) |
topic_facet |
Veterinary medicine SF600-1100 |
description |
The most common cardiac tumors of heart muscle are rhabdomyomas, solitary or multiple benign tumors of striated muscle origin. While cardiac rhabdomyomas are well described in human medical literature, limited information depicting the occurrence of cardiac rhabdomyomas in veterinary species exists. A case of multiple firm white nonencapsulated nodules in the heart of a bearded seal is described. Microscopic findings included cytoplasmic vacuolization with formation of spider cells, glycogen vacuoles, and striated myofibrils. These cells expressed immunoreactivity for neuron-specific enolase and protein gene product 9.5, a marker for neuronal tissue and Purkinje fiber cells. Immunoreactivity for protein gene product 9.5 along with other microscopic findings substantiates Purkinje fiber cell origin of the cardiac rhabdomyoma in the bearded seal and use of the term purkinjeoma to describe this lesion. |
format |
Article in Journal/Newspaper |
author |
G. Krafsur E. J. Ehrhart J. Ramos-Vara G. Mason F. Sarren B. Adams C. Hanns T. Spraker C. Duncan |
author_facet |
G. Krafsur E. J. Ehrhart J. Ramos-Vara G. Mason F. Sarren B. Adams C. Hanns T. Spraker C. Duncan |
author_sort |
G. Krafsur |
title |
Histomorphologic and Immunohistochemical Characterization of a Cardiac Purkinjeoma in a Bearded Seal (Erignathus barbatus) |
title_short |
Histomorphologic and Immunohistochemical Characterization of a Cardiac Purkinjeoma in a Bearded Seal (Erignathus barbatus) |
title_full |
Histomorphologic and Immunohistochemical Characterization of a Cardiac Purkinjeoma in a Bearded Seal (Erignathus barbatus) |
title_fullStr |
Histomorphologic and Immunohistochemical Characterization of a Cardiac Purkinjeoma in a Bearded Seal (Erignathus barbatus) |
title_full_unstemmed |
Histomorphologic and Immunohistochemical Characterization of a Cardiac Purkinjeoma in a Bearded Seal (Erignathus barbatus) |
title_sort |
histomorphologic and immunohistochemical characterization of a cardiac purkinjeoma in a bearded seal (erignathus barbatus) |
publisher |
Wiley |
publishDate |
2014 |
url |
https://doi.org/10.1155/2014/103279 https://doaj.org/article/b2284d3ca3eb419bb0061913a60460e9 |
genre |
bearded seal Erignathus barbatus |
genre_facet |
bearded seal Erignathus barbatus |
op_source |
Case Reports in Veterinary Medicine, Vol 2014 (2014) |
op_relation |
http://dx.doi.org/10.1155/2014/103279 https://doaj.org/toc/2090-7001 https://doaj.org/toc/2090-701X 2090-7001 2090-701X doi:10.1155/2014/103279 https://doaj.org/article/b2284d3ca3eb419bb0061913a60460e9 |
op_doi |
https://doi.org/10.1155/2014/103279 |
container_title |
Case Reports in Veterinary Medicine |
container_volume |
2014 |
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1 |
op_container_end_page |
4 |
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1810434708764360704 |